Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T77939 | WBC100
化合物 WBC100
|
2095780-08-6 | 98% |
|
WBC100(14-D-Valine-TPL),一款高效、选择性和具口服活性的c-Myc小分子降解剂,通过针对泛素E3连结酶CHIP介导的26S蛋白酶体途径实现其作用。主要应用于c-Myc过表达肿瘤的研究领域。 | ||||
T78055 | MYC-RIBOTAC
化合物 MYC-RIBOTAC
|
98% |
|
|
MYC-RIBOTAC 是一种针对MYC内部核糖体进入位点(IRES)的核糖核酸酶靶向降解剂(RIBOTAC)。该化合物结合了MYC mRNA的靶向组分以及一种可招募并激活RNA酶L1的小分子。通过降低MYC的mRNA和蛋白质表达水平,MYC-RIBOTAC诱导细胞发生凋亡,应用于抗肿瘤治疗的研究。 | ||||
T78986 | MDEG-541
化合物 MDEG-541
|
98% |
|
|
MDEG-541为一有效MYC-MAX降解剂,展现出显著的抗增殖活性,并有效降低GSPT1、MYC、GSPT2、PLK1蛋白表达水平。 | ||||
T79438 | C-Myc inhibitor 11
化合物 c-Myc inhibitor 11
|
98% |
|
|
c-Myc inhibitor11(Compound 67e),一种c-MYC抑制剂(pEC50: 6.4),在大鼠药代动力学评估中表现出高清除率、中等体积分布和短半衰期,适用于癌症研究领域。 | ||||
T79439 | C-Myc inhibitor 12
化合物 c-Myc inhibitor 12
|
98% |
|
|
c-Myc inhibitor12 (compound 67h),作为c-Myc抑制剂,具有pEC50值为6.4。 | ||||
T79872 | M-Se3
化合物 m-Se3
|
2829939-44-6 | 98% |
|
m-Se3 为一选择性c-MYC转录抑制剂,有效抑制肿瘤生长且表现出抗癌活性。 | ||||
T40419 | IRES-C11
化合物IRES-C11
|
342416-30-2 | 98% |
|
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ... | ||||
TN3708 | Coronarin D
化合物 TN3708
|
119188-37-3 | 98% |
|
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration... | ||||
TN2177 | Sanggenol L
桑根醇L
|
329319-20-2 | 98% |
|
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto... | ||||
TN4582 | Moracin T
化合物 TN4582
|
1146113-27-0 | 98% |
|
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc... | ||||
T16839 | SAJM589
化合物 T16839
|
2089-82-9 | 98% |
|
sAJM589 is a Myc inhibitor(IC50: 1.8 μM). | ||||
T11783 | KSI-3716
化合物 T11783
|
1151813-61-4 | 98% |
|
KSI-3716 is an inhibitor of c-Myc. | ||||
TN1354 | Aaptamine
化合物Aaptamine
|
85547-22-4 | 98% |
|
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner. | ||||
T10702 | CBP/p300-IN-2
化合物 T10702
|
2158265-96-2 | 98% |
|
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc). | ||||
TN4581 | Moracin D
化合物 TN4581
|
69120-07-6 | 98% |
|
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o... | ||||
T60019 | VPC-70063
化合物VPC-70063
|
13571-44-3 | 99.93% |
|
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) 是 c-Myc-MAX 的抑制剂。 VPC-70063 的 Myc-Max 转录活性抑制率为 106%,IC50 为 8.9 μM,Myc-Max/UBE2C 下游通路抑... | ||||
T9033 | BTYNB
化合物MDK6620
|
304456-62-0 | 99.91% |
|
BTYNB (MDK6620) 是IMP1结合 c-Myc mRNA 的有效选择性抑制剂,IC50为 5 μM。它下调 β-TrCP1 mRNA 并减少NF-κB 的激活。它通过损害 IGF2 mRNA 结合蛋白 1 结合来破坏这种增强子功能,可用于癌症研究。 | ||||
T0617 | Nicotinamide N-oxide
烟酰胺-N-氧化物
|
1986-81-8 | 99.9% |
|
Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物,是高效选择性CXCR2受体拮抗剂。 | ||||
T3048 | 10058-F4
化合物10058-F4
|
403811-55-2 | 99.82% |
|
10058-F4 (c-Myc Inhibitor) 是一种细胞渗透性噻唑烷酮,可特异性抑制 c-Myc-Max 相互作用并防止 c-Myc 靶基因表达的反式激活;诱导细胞周期停滞和凋亡。 | ||||
T9093 | NY2267
化合物NY2267
|
886053-73-2 | 99.6% |
|
NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester... |