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Tyrosinase

Tyrosinase

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesised in the skin melanocytes.
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Cat. No. Product Name CAS No. Purity Chemical Structure
TN4642 Neorauflavane
化合物 TN4642
53734-74-0 98%
Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content...
TN4580 Morachalcone A
化合物 TN4580
76472-88-3 97.00%
Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 u...
TC0017 Haplopine
化合物 TC0017
5876-17-5
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
TN1840 Kurarinol
苦参醇
855746-98-4 98%
Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying...
TN2672 2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran
化合物 TN2672
67736-22-5 98%
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
T37961 P-Tolualdehyde
对甲苯醛
104-87-0 98%
p-Tolualdehyde 是一种 RIFM 香料,对蘑菇酪氨酸酶显示出抑制作用。
T79401 Tyrosinase-IN-13
化合物 Tyrosinase-IN-13
98%
Tyrosinase-IN-13 (compound 3c)为Flurbiprofen的衍生物,具有非竞争性酪氨酸酶抑制活性(IC50=68 μM;Ki=36.3 μM),并对肝细胞癌(HepG2)、结直肠癌(HT-29)及黑色素瘤(B16F10)细胞表现出细胞毒性。
T79406 Tyrosinase-IN-14
化合物 Tyrosinase-IN-14
98%
Tyrosinase-IN-14 (compound 7m) 是一种针对酪氨酸酶的抑制剂, 它通过改变酪氨酸酶的二级结构来降低其催化活性。此化合物的细胞毒性较低, 并且在水果抗褐变方面显示出活性。特别是,Tyrosinase-IN-14 在抑制香蕉储藏期间的褐变方面表现出了有效性。
T80203 Diaminopropionoyl tripeptide-33
化合物 Diaminopropionoyl tripeptide-33
1199495-15-2 98%
Diaminopropionoyl tripeptide-33为生物活性肽,能保护皮肤细胞不受UVA引发的DNA损伤,已报道在化妆品成分中应用。
T80909 Tyrosinase-IN-19
化合物 Tyrosinase-IN-19
98%
Tyrosinase-IN-19 是竞争性酪氨酸酶抑制剂,对ROS、ABTS+ 及DPPH 自由基展现显著的抗氧化活性。该化合物通过剂量依赖性方式有效抑制酪氨酸酶表达。
T80910 Tyrosinase-IN-15
化合物 Tyrosinase-IN-15
98%
Tyrosinase-IN-15 (Compound 39)为酪氨酸酶抑制剂,具有IC50值为7.12 μM及Ki值为11.8 μM。
TN5117 Taxiphyllin
化合物 TN5117
21401-21-8 98%
Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against...
TN3540 Broussonin C
化合物 TN3540
76045-49-3 98%
Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
TN2303 Viscumneoside III
槲寄生新苷III
118985-27-6 98%
Viscumneoside III 是一种二氢黄酮 O-糖苷,抑制酪氨酸酶 (tyrosinase),IC50 为 0.5 mM。Viscumneoside III 具有抗心绞痛作用。
TN3644 Chlorophorin
化合物 TN3644
537-41-7 98%
Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of...
TN2288 Uralenol
化合物 TN2288
139163-15-8 98%
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
TN2280 Trametenolic acid
3-羟基羊毛甾-8,24-二烯-21-酸
24160-36-9 98%
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
TN1314 6-Hydroxykaempferol
6-羟基山奈酚
4324-55-4 98%
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
T2S0799 Noroxyhydrastinine
化合物 T2S0799
21796-14-5 98%
Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein leve...
T10664 Calcium 2-oxoglutarate
化合物 T10664
71686-01-6 98%
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
Neorauflavane
TN4642
Neorauflavane shows tyrosinase inhibition, it can inhibit tyrosinase monophenolase activity with an IC50 of 30 nM, it also can efficiently reduce melanin content...
Morachalcone A
TN4580
Morachalcone A displays significant tyrosinase inhibitory activity (IC50, 0.013 uM); it also exerts strong pancreatic lipase inhibition with IC 50 value of 6.2 u...
Haplopine
TC0017
Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the c...
Kurarinol
TN1840
Kurarinol is a potent inhibitor of sortase A, with an IC50 value of 107.7 ± 6.6 μM. Kurarinol has extremely strong tyrosinase inhibitory activity, exerts varying...
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran
TN2672
2-(2,4-Dihydroxyphenyl)-6-hydroxybenzofuran shows radical scavenging activities. It also shows mushroom tyrosinase inhibitory activity with an IC50 value of 5.2 ...
P-Tolualdehyde
T37961
p-Tolualdehyde 是一种 RIFM 香料,对蘑菇酪氨酸酶显示出抑制作用。
Tyrosinase-IN-13
T79401
Tyrosinase-IN-13 (compound 3c)为Flurbiprofen的衍生物,具有非竞争性酪氨酸酶抑制活性(IC50=68 μM;Ki=36.3 μM),并对肝细胞癌(HepG2)、结直肠癌(HT-29)及黑色素瘤(B16F10)细胞表现出细胞毒性。
Tyrosinase-IN-14
T79406
Tyrosinase-IN-14 (compound 7m) 是一种针对酪氨酸酶的抑制剂, 它通过改变酪氨酸酶的二级结构来降低其催化活性。此化合物的细胞毒性较低, 并且在水果抗褐变方面显示出活性。特别是,Tyrosinase-IN-14 在抑制香蕉储藏期间的褐变方面表现出了有效性。
Diaminopropionoyl tripeptide-33
T80203
Diaminopropionoyl tripeptide-33为生物活性肽,能保护皮肤细胞不受UVA引发的DNA损伤,已报道在化妆品成分中应用。
Tyrosinase-IN-19
T80909
Tyrosinase-IN-19 是竞争性酪氨酸酶抑制剂,对ROS、ABTS+ 及DPPH 自由基展现显著的抗氧化活性。该化合物通过剂量依赖性方式有效抑制酪氨酸酶表达。
Tyrosinase-IN-15
T80910
Tyrosinase-IN-15 (Compound 39)为酪氨酸酶抑制剂,具有IC50值为7.12 μM及Ki值为11.8 μM。
Taxiphyllin
TN5117
Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against...
Broussonin C
TN3540
Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
Viscumneoside III
TN2303
Viscumneoside III 是一种二氢黄酮 O-糖苷,抑制酪氨酸酶 (tyrosinase),IC50 为 0.5 mM。Viscumneoside III 具有抗心绞痛作用。
Chlorophorin
TN3644
Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of...
Uralenol
TN2288
Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as s...
Trametenolic acid
TN2280
Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9μM, K IS of 0.5μM, and an IC50 of 7.25μM.Trametenolic acid and Bet...
6-Hydroxykaempferol
TN1314
6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
Noroxyhydrastinine
T2S0799
Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein leve...
Calcium 2-oxoglutarate
T10664
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
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