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Telomerase
T10574 BMVC BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (IC50: ~2.5 μM).
T10760 Ceramides Mixture Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibi
T13115 Telomerase-IN-2 Telomerase-IN-2 is an inhibitor of telomerase, and inhibits telomerase activity by decreasing expression of dyskerin(IC50 of 0.89 µM), with anti-cancer activity.
T13504 360A iodide 360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).
T1416 Zidovudine Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA re
T2380 BIBR 1532 BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).
T2902 Costunolide Costunolide has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T3182 L-778123 hydrochloride The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
T3333 Cycloastragenol Cycloastragenol is able to elongate telomeres, resulting in increased lifespan of the animals.
T7409 360A 360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
T7447 Adefovir Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.
TN4443 Lipiferolide Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against
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