Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T13182 | Toll-like receptor modulator
化合物 T13182
|
926927-42-6 | 98% |
|
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function. | ||||
TN3587 | Capillarisin
化合物 TN3587
|
56365-38-9 | 98% |
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell... | ||||
TP2282L | Pam2CSK4 TFA
Pam2CSK4三氟乙酸盐
|
98% |
|
|
Pam2CSK4 TFA (PUL-042 TFA) 是一种有效的 TLR2 和 TLR6 双重激动剂,是一种模拟细菌脂蛋白的多肽。Pam2CSK4 TFA 可促进血小板聚集,可用来研究脂蛋白对牙周的影响。 | ||||
TP1938 | RS 09
化合物RS 09
|
1449566-36-2 | 98% |
|
RS 09 是一种 LPS 肽模拟物,是 TLR4 激动剂佐剂,可在疫苗环境中增加抗体产量。 | ||||
T10437 | AZD8848
化合物 T10437
|
866269-28-5 | 98% |
|
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis. | ||||
T13168 | TLR7 agonist 1
化合物 T13168
|
2178156-33-5 | 98% |
|
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM). | ||||
T16870 | Selgantolimod
化合物 T16870
|
2004677-13-6 | 98% |
|
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection. | ||||
T14035 | 3M-011
化合物 T14035
|
642473-62-9 | 98% |
|
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy... | ||||
T38635 | Kdo2-Lipid A ammonium
Kdo2-Lipid A铵盐
|
1246298-62-3 | 98% |
|
Kdo2-Lipid A ammonium (KLA) 是一种具有选择性和有效性的 TLR4 激动剂,属于一种脂多糖。Kdo2-Lipid A ammonium 促使 TNF 和 PGE2 的释放。 | ||||
T72035 | TLR7/8/9 antagonist 2
TLR7/8/9拮抗剂2
|
2920729-91-3 | 98% |
|
TLR7/8/9 antagonist 2 是一种具有口服活性和较高生物利用度的 vTLR7/8/9 拮抗剂。TLR7/8/9 antagonist 2 对 HEK/hTLR7、HEK/hTLR8 和 HEK/hTLR9 具有抑制作用,IC50 分别为 0.011 μM、0.029 μM 和 0,052 μM。TLR7/... | ||||
TN5138 | Teuclatriol
化合物 TN5138
|
152110-17-3 | 98% |
|
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312... | ||||
T15751 | LHC-165
化合物 T15751
|
1258595-14-0 | 98% |
|
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors. | ||||
T15017 | CU-T12-9
化合物CU-T12-9
|
1821387-73-8 | 99.93% |
|
CU-T12-9 是特异性 TLR1/2激动剂,可激活先天免疫系统和适应性免疫系统。它选择性激活 TLR1/2 异二聚体,可通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号,引起下游 TNF-α、IL-10 和 iNOS 增加。 | ||||
T13167 | TLR7/8 agonist 3
化合物TLR7/8 agonist 3
|
642473-95-8 | 99.93% |
|
TLR7/8 agonist 3 是TLR7/8激动剂,详细信息来源于专利文献 WO2016057618,化合物 II。 | ||||
T6846 | Vesatolimod
维沙莫德
|
1228585-88-3 | 99.92% |
|
Vesatolimod (GS-9620) 是一种选择性 Toll 样受体 7 口服激动剂,EC50值为291 nM。 | ||||
T0951 | Hydroxychloroquine sulfate
硫酸羟氯喹
|
747-36-4 | 99.87% |
|
Hydroxychloroquine sulfate (Acidum iopanoicum) 抑制疟原虫血红素聚合酶。它还可抑制 Toll 样受体 7/9 信号传导和 SARS-CoV-2 感染。 | ||||
T38078 | TLR7/8-IN-1
化合物TLR7/8-IN-1
|
2205095-75-4 | 99.80% |
|
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor obtained from patent WO2019220390 (compound 2b), is a valuable compound for autoimmune disease research[1]. | ||||
T6964 | Resiquimod
雷西莫特
|
144875-48-9 | 99.78% |
|
Resiquimod (R848) 是一种 Toll 样受体7/8的激动剂,可诱导细胞因子上调。 | ||||
T72253 | AXC-715 trihydrochloride
AXC-715盐酸盐
|
2479276-17-8 | 99.74% |
|
AXC-715 trihydrochloride (T785 trihydrochloride) 是一种 TLR7/TLR8 双激动剂, 可用于合成抗体佐剂免疫偶联物。偶联物多为程序性死亡配体 1 (PD-L1) 连接到一个或多个佐剂的抗体结构上。 | ||||
T5521 | Bropirimine
溴匹立明
|
56741-95-8 | 99.74% |
|
Bropirimine (U-54461) 是 toll 样受体 7(TLR7)的合成激动剂,可通过 TLR7 介导 IFN-β 的产生抑制破骨细胞前体细胞向破骨细胞分化。它是一种生物反应调节剂,通过诱导淋巴因子起作用,在膀胱和上尿路的原位移行细胞癌中具有抗癌活性。 |