首页 工具
登录
购物车
TLR

TLR

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-pass membrane-spanning receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes.
1 2 3 4 5
Cat. No. Product Name CAS No. Purity Chemical Structure
T13182 Toll-like receptor modulator
化合物 T13182
926927-42-6 98%
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
TN3587 Capillarisin
化合物 TN3587
56365-38-9 98%
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
TP2282L Pam2CSK4 TFA
Pam2CSK4三氟乙酸盐
98%
Pam2CSK4 TFA (PUL-042 TFA) 是一种有效的 TLR2 和 TLR6 双重激动剂,是一种模拟细菌脂蛋白的多肽。Pam2CSK4 TFA 可促进血小板聚集,可用来研究脂蛋白对牙周的影响。
TP1938 RS 09
化合物RS 09
1449566-36-2 98%
RS 09 是一种 LPS 肽模拟物,是 TLR4 激动剂佐剂,可在疫苗环境中增加抗体产量。
T10437 AZD8848
化合物 T10437
866269-28-5 98%
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
T13168 TLR7 agonist 1
化合物 T13168
2178156-33-5 98%
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
T16870 Selgantolimod
化合物 T16870
2004677-13-6 98%
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
T14035 3M-011
化合物 T14035
642473-62-9 98%
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
T38635 Kdo2-Lipid A ammonium
Kdo2-Lipid A铵盐
1246298-62-3 98%
Kdo2-Lipid A ammonium (KLA) 是一种具有选择性和有效性的 TLR4 激动剂,属于一种脂多糖。Kdo2-Lipid A ammonium 促使 TNF 和 PGE2 的释放。
T72035 TLR7/8/9 antagonist 2
TLR7/8/9拮抗剂2
2920729-91-3 98%
TLR7/8/9 antagonist 2 是一种具有口服活性和较高生物利用度的 vTLR7/8/9 拮抗剂。TLR7/8/9 antagonist 2 对 HEK/hTLR7、HEK/hTLR8 和 HEK/hTLR9 具有抑制作用,IC50 分别为 0.011 μM、0.029 μM 和 0,052 μM。TLR7/...
TN5138 Teuclatriol
化合物 TN5138
152110-17-3 98%
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312...
T15751 LHC-165
化合物 T15751
1258595-14-0 98%
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
T15017 CU-T12-9
化合物CU-T12-9
1821387-73-8 99.93%
CU-T12-9 是特异性 TLR1/2激动剂,可激活先天免疫系统和适应性免疫系统。它选择性激活 TLR1/2 异二聚体,可通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号,引起下游 TNF-α、IL-10 和 iNOS 增加。
T13167 TLR7/8 agonist 3
化合物TLR7/8 agonist 3
642473-95-8 99.93%
TLR7/8 agonist 3 是TLR7/8激动剂,详细信息来源于专利文献 WO2016057618,化合物 II。
T6846 Vesatolimod
维沙莫德
1228585-88-3 99.92%
Vesatolimod (GS-9620) 是一种选择性 Toll 样受体 7 口服激动剂,EC50值为291 nM。
T0951 Hydroxychloroquine sulfate
硫酸羟氯喹
747-36-4 99.87%
Hydroxychloroquine sulfate (Acidum iopanoicum) 抑制疟原虫血红素聚合酶。它还可抑制 Toll 样受体 7/9 信号传导和 SARS-CoV-2 感染。
T38078 TLR7/8-IN-1
化合物TLR7/8-IN-1
2205095-75-4 99.80%
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor obtained from patent WO2019220390 (compound 2b), is a valuable compound for autoimmune disease research[1].
T6964 Resiquimod
雷西莫特
144875-48-9 99.78%
Resiquimod (R848) 是一种 Toll 样受体7/8的激动剂,可诱导细胞因子上调。
T72253 AXC-715 trihydrochloride
AXC-715盐酸盐
2479276-17-8 99.74%
AXC-715 trihydrochloride (T785 trihydrochloride) 是一种 TLR7/TLR8 双激动剂, 可用于合成抗体佐剂免疫偶联物。偶联物多为程序性死亡配体 1 (PD-L1) 连接到一个或多个佐剂的抗体结构上。
T5521 Bropirimine
溴匹立明
56741-95-8 99.74%
Bropirimine (U-54461) 是 toll 样受体 7(TLR7)的合成激动剂,可通过 TLR7 介导 IFN-β 的产生抑制破骨细胞前体细胞向破骨细胞分化。它是一种生物反应调节剂,通过诱导淋巴因子起作用,在膀胱和上尿路的原位移行细胞癌中具有抗癌活性。
Toll-like receptor modulator
T13182
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
Capillarisin
TN3587
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
Pam2CSK4 TFA
TP2282L
Pam2CSK4 TFA (PUL-042 TFA) 是一种有效的 TLR2 和 TLR6 双重激动剂,是一种模拟细菌脂蛋白的多肽。Pam2CSK4 TFA 可促进血小板聚集,可用来研究脂蛋白对牙周的影响。
RS 09
TP1938
RS 09 是一种 LPS 肽模拟物,是 TLR4 激动剂佐剂,可在疫苗环境中增加抗体产量。
AZD8848
T10437
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
TLR7 agonist 1
T13168
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
Selgantolimod
T16870
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
3M-011
T14035
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
Kdo2-Lipid A ammonium
T38635
Kdo2-Lipid A ammonium (KLA) 是一种具有选择性和有效性的 TLR4 激动剂,属于一种脂多糖。Kdo2-Lipid A ammonium 促使 TNF 和 PGE2 的释放。
TLR7/8/9 antagonist 2
T72035
TLR7/8/9 antagonist 2 是一种具有口服活性和较高生物利用度的 vTLR7/8/9 拮抗剂。TLR7/8/9 antagonist 2 对 HEK/hTLR7、HEK/hTLR8 和 HEK/hTLR9 具有抑制作用,IC50 分别为 0.011 μM、0.029 μM 和 0,052 μM。TLR7/...
Teuclatriol
TN5138
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312...
LHC-165
T15751
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
CU-T12-9
T15017
CU-T12-9 是特异性 TLR1/2激动剂,可激活先天免疫系统和适应性免疫系统。它选择性激活 TLR1/2 异二聚体,可通过促进 TLR1 和 TLR2 二聚而激活 NF-κB 信号,引起下游 TNF-α、IL-10 和 iNOS 增加。
TLR7/8 agonist 3
T13167
TLR7/8 agonist 3 是TLR7/8激动剂,详细信息来源于专利文献 WO2016057618,化合物 II。
Vesatolimod
T6846
Vesatolimod (GS-9620) 是一种选择性 Toll 样受体 7 口服激动剂,EC50值为291 nM。
Hydroxychloroquine sulfate
T0951
Hydroxychloroquine sulfate (Acidum iopanoicum) 抑制疟原虫血红素聚合酶。它还可抑制 Toll 样受体 7/9 信号传导和 SARS-CoV-2 感染。
TLR7/8-IN-1
T38078
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor obtained from patent WO2019220390 (compound 2b), is a valuable compound for autoimmune disease research[1].
Resiquimod
T6964
Resiquimod (R848) 是一种 Toll 样受体7/8的激动剂,可诱导细胞因子上调。
AXC-715 trihydrochloride
T72253
AXC-715 trihydrochloride (T785 trihydrochloride) 是一种 TLR7/TLR8 双激动剂, 可用于合成抗体佐剂免疫偶联物。偶联物多为程序性死亡配体 1 (PD-L1) 连接到一个或多个佐剂的抗体结构上。
Bropirimine
T5521
Bropirimine (U-54461) 是 toll 样受体 7(TLR7)的合成激动剂,可通过 TLR7 介导 IFN-β 的产生抑制破骨细胞前体细胞向破骨细胞分化。它是一种生物反应调节剂,通过诱导淋巴因子起作用,在膀胱和上尿路的原位移行细胞癌中具有抗癌活性。
1 2 3 4 5
联系我们
400-820-0310

上海市静安区江场三路238号8楼