||Amitriptyline Hydrochloride is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
||Sigma-1 receptor antagonist 2
||Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
||Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
||PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki: 0.08 nM and 1377 nM for σ1 and σ2 respe
||BD-1047 hydrobromide, a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
||S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM) antagonist, showed good selectivity against σ2R (Ki > 1000 nM).
||Siramesine (Lu 28-179) hydrochloride is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in v
||Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
||Glycerol phenylbutyrate-D5 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
||PRE-084 hydrochloride is a high affinity, selective σ1 agonist.
||PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
||Cutamesine dihydrochloride is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibits angiotensin II-induced cardiomyocyt
||Anavex 2-73 is a Sigma-1 Receptor agonist (IC50: 860 nM).
||S1RA HCl (E-52862 HCl) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki > 1000 nM).
||4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .
||Dimemorfan phosphate is a sigma 1 receptor agonist, used as a potent antitussive.
||Ditolylguanidine is an agonist of sigma receptor (σ1/σ2 receptor).
||BD1063 is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
||Noscapine is a Non-addictive Opioid and Microtubule-Inhibitor in Potential Treatment of Glioblastoma.
||EST64454 is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.