||SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. Antitumor activity.
||MSA-2 is a potent and orally available non-nucleotide STING agonist.
||STING agonist-1 is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
||C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
||H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
||diABZI STING agonist-1 trihydrochloride
||diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
||Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
||C-176 is a highly potent and covalent mouse STING inhibitor.
||ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphor