T8689 |
CHLOROQUINE |
Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthrit |
T12502 |
PLpro inhibitor |
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM) |
T11464 |
GRL0617 |
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM). |
T3S0136 |
O-Methylbroussochalcone B |
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T8688 |
CPD77 |
CPD77 is a potent SARS-CoV-2 main protease inhibitor. |
T8419 |
XP-59 |
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM). |
T8371 |
ML188 |
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity. |
T8309 |
EIDD-2801 |
EIDD-2801 is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviruses activity. |
T7766 |
Remdesivir |
Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells) |