Rho

Rho protein functions as a hexamer of a single polypeptide chain with 419 residues, which is the product of the rho gene. It is an RNA-binding protein with the capacity to hydrolyze ATP and other nucleoside triphosphates.

产品编号	产品名称
T22062	CCG-100602	CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 µM).
T7391	SAR407899	SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
T6739	Zoledronic Acid	Zoledronate is a bisphosphonate. Zometa is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also...
T2427	EHop016	EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
T2014	CCG1423	CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
T3553	Y16	Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated s...
T1237	Azathioprine	Azathioprine, an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
T6483	EHT 1864	EHT 1864 is a effective Rac family GTPase inhibitor for Rac1/Rac1b/Rac2/Rac3 (Kd: 40/50/60/250 nM).
T4306	CCG203971	CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. T...
T7764	CCG-222740	CCG-222740 is an inhibitor of Rho/MRTF pathway
TP2327L	Y16 acetate(53-73-6 free base)	Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated s...
T12452	Digeranyl bisphosphonate	Digeranyl bisphosphonate is a potent inhibitor of geranylgeranylpyrophosphate (GGPP) synthase.
T14004	1A-116	1A-116 is a specific inhibitor of Rac1 .
T16745	Rhosin hydrochloride	Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ ...
T16746	Rhosin	Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosi...
TP2131L	Rac1 Inhibitor W56 acetate(1095179-01-3 free base)	Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction wit...
TP2130L	Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base)	Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does no...
TP2327L	Y16 acetate(53-73-6 free base)	Y16 is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA activation, and RhoA-mediated s...
T6342	NSC 23766 trihydrochloride	NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.