| T10374 | ARS-1323-alkyne | ARS-1323-alkyne is a switch-II pocket (S-IIP) inhibitor and a conformational specific chemical reporter of KRASG12C nucleotide state in living cells. |
| T10375 | ARS-1323 | ARS-1323 (the racemate of ARS-1620) is a mutant K-ras G12C inhibitor extracted from patent WO 2015054572 A1. |
| T10376 | ARS-1630 | ARS-1630 is a mutant K-ras G12C inhibitor extracted from patent WO 2015054572 A1. It is a less active enantiomer of ARS-1620. |
| T10533 | BI-2852 | BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative eff |
| T11744 | KB-5246 | KB-5246, displays antibacterial activities.is a tetracyclic quinolone. |
| T11767 | KRAS G12C inhibitor 13 | KRAS G12C inhibitor 13 is a KRAS G12C inhibitor . |
| T11768 | KRAS G12C inhibitor 14 | KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor . |
| T11769 | KRAS G12C inhibitor 15 | KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor . |
| T11770 | KRAS G12C inhibitor 16 | KRAS G12C inhibitor 16 is a potent KRAS G12C inhibitor. |
| T11771 | KRAS G12C inhibitor 17 | KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor. |
| T11773 | KRAS inhibitor-6 | KRAS inhibitor-6 is a potent KRAS G12C inhibitor. |
| T11774 | KRAS inhibitor-7 | KRAS inhibitor-7 is a potent KRAS G12C inhibitor. |
| T11775 | KRAS inhibitor-8 | KRAS inhibitor-8 is a potent KRAS G12C inhibitor. |
| T11776 | KRas G12C inhibitor 1 | KRas G12C inhibitor 1 is a compound that inhibits KRas G12C. |
| T11777 | KRas G12C inhibitor 2 | KRas G12C inhibitor 2 is a compound that inhibits KRas G12C. |
| T11778 | KRas G12C inhibitor 3 | KRas G12C inhibitor 3 is a compound that inhibits KRas G12C. |
| T11779 | KRas G12C inhibitor 4 | KRas G12C inhibitor 4 is a compound that inhibits KRas G12C. |
| T11780 | KRAS G12C inhibitor 5 | KRAS G12C inhibitor 5 is a KRas G12C inhibitor. |
| T12979 | BI-3406 | BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity. |
| T13844 | PROTAC K-Ras Degrader-1 | PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC. |
| T16023 | MC 976 | MC 976 is a derivative of Vitamin D3. |
| T16143 | MRTX-1257 | MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells.MRTX1257 demonstrated 31 |
| T22249 | 1588-A4 | 1588-A4 is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics. |
| T22258 | AMG-510 racemate | AMG-510 racemate is a racemic of AMG-510 which is a potent inhibitor of KRAS G12C covalent, and leading to potential antineoplastic activity. |
| T4619 | ML098 | ML-098 is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM). |
| T5379 | Antineoplaston A10 | Antineoplaston A10 is a naturally occurring substance and the first antineoplaston in the human body to be chemically identified. It displayed anti-proliferative action inhibiting |
| T5469 | K-Ras-IN-1 | K-Ras-IN-1 is a K-Ras inhibitor. |
| T6163 | Salirasib | Salirasib(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity. |
| T6302 | Lonafarnib | Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM). |
| T7131 | Antineoplaston A10 | Antineoplaston A 10 is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. |
| T7326 | 6H05 TFA | 6H05 TFA is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor. |
| T7328 | AMG-510 | AMG-510 is a potent KRAS G12C covalent inhibitor, treatment with AMG 510 led to the regression of KRASG12C tumours and improved the anti-tumour efficacy of chemotherapy and target |
| T7558 | CID-1067700 | CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM). |
| T7609 | ARS-1620 | ARS-1620 is a covalent inhibitor of K-RASG12C. |
| T8006 | Oncrasin 1 | Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations |
| T8369 | MRTX849 | MRTX849 is a potent, selective, and covalent KRASG12C inhibitor with potential antineoplastic activity.selectively modifies mutant cysteine 12 in GDP-bound KRASG12C, and inhibits K |
| T8375 | ML-210 | ML-210 is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity |
| T8684 | AMG-510 | AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor. |
| T8756 | KRAS inhibitor-9 | KRAS inhibitor-9 is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle ar |
| T8756 | KRAS inhibitor-9 | KRAS inhibitor-9 is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle ar |
| T8843 | APS6-45 | APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity. |
| T8870 | 1-(4-methansulfinylphenyl)ethanone | The compound inhibits Ras function and therefore inhibits the abnormal growth of cells. |
