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T0180 Benazepril hydrochloride Benazepril is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril is associated with a low rate of transient serum aminotransfer
T0215 Losartan potassium Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
T0215L Losartan Losartan is an angiotensin II receptor antagonist.
T0706 Lisinopril dihydrate Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T0805 Quinapril hydrochloride Quinapril is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril is associated with a low rate of transient
T10323 Angiotensin II (3-8), human TFA Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
T1057 Azilsartan Azilsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect of azilsartan is by
T11642 Imidaprilate Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin-converting enzyme (ACE) inhibitor (IC50: 2.6 nM). It is used in the research of the hypertensive disea
T11808 L162389 L162389 is a potent angiotensin AT1 receptor antagonist with Ki of 28 nM.
T11809 L162441 L162441 is an antagonist of Angiotensin type 1 receptor.
T12704 Rentiapril Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.
T13865 Resorcinolnaphthalein Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
T14123 ACT 178882 ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).
T1461 Candesartan Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T1462 Captopril Captopril is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of ar
T1484 Perindoprilat Perindoprilat is an angiotensin-converting enzyme inhibitor.
T1484L Perindopril erbumine Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. U
T1489 Fosinopril sodium Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to i
T1518 Olmesartan Medoxomil Olmesartan medoxomil is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
T1520 Aliskiren hemifumarate Aliskiren Hemifumarate is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T1570 Telmisartan Telmisartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
T1605 Enalapril Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1615 Irbesartan Irbesartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T16385 Omapatrilat Omapatrilat is a metalloprotease ACE and NEP dual inhibitor (Ki: 0.64 and 0.45 nM, respectively).
T1645 Ramipril Ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
T16544 Pivalopril Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.
T16573 Pratosartan Pratosartan is a selective antagonist of angiotensin II receptor.
T19187 Aliskiren D6 hemifumarate Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).
T1940 BTB06584 BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against
T21418 Lisinopril Lisinopril, the angiotensin-converting enzyme (ACE) inhibitor, is used primarily in the treatment of high heart failure, blood pressure, and heart attacks. It is also used for prev
T2270 Trans-Tranilast Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hyp
T2318 LCZ696 LCZ696 is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
T2321 Protodioscin Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
T2321 Protodioscin Protodioscin is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties.
T2322 Fimasartan Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic
T2400 Candesartan Cilexetil Candesartan Cilexetil is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesa
T2531 Eprosartan Mesylate Eprosartan is a competitive and reversible Angiotensin II Receptor Blocker.
T3064 VTP27999 VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
T3178 BIBS 39 BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
T3281 Delapril Hydrochloride Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-conv
T3461 Losartan Carboxylic Acid EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, is more potent than l
T3753 Sinapinic Acid Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cyt
T3753 Sinapinic Acid Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cyt
T3851 Vicenin -2 Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B,
T4431 EMA401 EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and spr
T5030 Zofenopril (calcium) Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yieldin
T5355 Sparsentan Sparsentan is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respectively)
T5701 OPHIOPOGONIN D Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
T5796 Plantainoside D Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) v
T5824 ANGIOTENSIN IV Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
T5964 Olmesartan Olmesartan is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihypertensive activity.
T6067 PD123319 PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist.
T6133 Remodelin hydrobromide Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
T6219 Azilsartan Medoxomil Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hyperte
T6340 Enalaprilat Dihydrate Enalaprilat(IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.
T6444 Cilazapril Monohydrate Cilazapril Monohydrate is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
T6486 Enalapril Maleate Enalapril Maleate, an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
T6542 Imidapril HCl Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T6595 Moexipril HCl Moexipril HCl is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
T6698 Temocapril HCl Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T6716 Valsartan Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
T7040 Angiotensin II human Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I convert Angiotensin II
T7339 Angiotensin 1-7 Angiotensin 1-7, also known as Ang-(1-7), is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodil
T7354 H-Val-Pro-Pro-OH H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).
T7510 Leucylarginylproline Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).
T7577 Angiotensin III, human, mouse(3TFA) Angiotensin III, human, mouse(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
T7616 A 779 A 779(3TFA) is a potent antagonist of angiotensin-(1-7) receptor
T7616L A 779 TFA(159432-28-7 free base) A 779(3TFA) is a potent antagonist of angiotensin-(1-7) receptor
T7668 VTP-27999 TFA VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
T7686 Ramiprilat Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T7743 ANGIOTENSIN IV TFA(12676-15-2(free base)) ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.
T7797 Tasosartan Tasosartan is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
T7808 Alacepril Alacepril is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive
T8270 Deserpidine Deserpidine is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic a
T8560 Angiotensin II acetate Angiotensin II acetate is a vasoconstrictor that mainly acts on the AT1 receptor.
TN1464 Camellianin A Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dos
TN4431 Leucosceptoside A Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside
TP1016L Aviptadil Acetate Avitadil acetate induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmonary fib
TP1187 CNP (1-22), human C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.
TP1622 DX600 TFA DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.
TP1828 N-Acetyl-Ser-Asp-Lys-Pro Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell
TP2158 TRV-120027 TFA TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
TQ0057 AVE 0991 AVE 0991 is a small molecular and orally active agonist of angiotensin-(1-7) receptor (IC50: 21 nM).
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