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NAMPT
T11823 LB-60-OF61 LB-60-OF61, a NAMPT inhibitor, is a cytotoxic compound that is selective to MYC overexpressed cell lines.
T12171 Nampt-IN-5 Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
T12330 OT-82 OT-82 is a potent, selective and orally active NAMPT inhibitor.
T12854 SBI-797812 SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
T15403 GNE-618 GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM). GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor
T1998 CHS 828 GMX1778(CHS-828), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).
T4335 GNE617 GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.
T4354 KPT9274 KPT-9274 is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.
T4376 Nampt-IN-1 Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
T6682 STF118804 STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
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