首页AutophagyNADPH-oxidase
NADPH-oxidase
T0679 Ketoconazole Ketoconazole, a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
T6099 GKT137831 GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T8107 GLX351322 GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T8408 GKT136901 GKT136901 is an  inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
TN1208 2-Amino-3-carboxy-1,4-naphthoquinone 2-Amino-3-carboxy-1,4-naphthoquinone is a novel growth stimulator for bifidobacteria, it affects the end-product profile of bifidobacteria through the mediated oxidation of NAD(P)H
TN1503 Cistanoside F Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthin
TN1645 Flavokawain C Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cycle and promoted apop
TN2036 Paeonilactone B Paeonilactone B is a natural product from Paeonia albiflora.
TN2126 Quercetin-3-O-glucose-6''-acetate Quercetin-3-O-glucose-6''-acetate is a NADPH oxidase inhibitor, it has antioxidant capacity.
TN1542 Cycloheterophyllin Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be used in the research
T10354 APX-115 APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents k
T10353 APX-115 free base APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 ef
TJS1779 Protosappanin A Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal path
TN2766 2'-Hydroxydaidzein 2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of central and peripheral inf
TN3069 4beta-Carboxy-19-nortotarol 4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits l
TMA0033 5'-Demethylaquillochin 5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive agents through induction of detoxification enzymes. 5'-Dem
TN3112 5-Heneicosylresorcinol 5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cells. 5-Heneicosylreso
TN3294 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.
TN3300 8alpha-Tigloyloxyhirsutinolide 13-O-acetate 8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has anti-cancer activit
TN3469 Aucuparin Aucuparin is a phytoalexin, it shows significant scavenging activity by the ABTS and FRAP assays. Aucuparin exhibits potent inhibitory activity against fMLP-induced superoxide (O(*
TN3627 Chalepensin Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction thr
TN4227 Horminone Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi, 30 microM drug con
TN4317 Isopedicin Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation of cellular cAMP and activation of PKA through its inhibition
TN4635 Neoechinulin A Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation o
TN4800 Pisatin Pisatin is an isoflavonoid phytoalexin synthesized by pea (Pisum sativum L.).
TN4889 (R)-Reticuline (R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids.
TN4905 Rehmannic acid Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent uncouplers, abolishing the phosphate uptake, the respiration bei
TMA1570 Sappanone A Sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. It exerts its anti-inflammatory effect by modulating the Nrf2 and NF-κB pathwa
TN5050 Sprengerinin C Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tum
TN5156 Totaradiol Totaradiol shows antioxidant activity, it can inhibit linoleic acid autoxidation but not generation of superoxide anion. Totaradiol exhibits cytotoxic activity against the A2780 ov
TN5243 Vitexilactone Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has tr
TN5278 Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of
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