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Kinesin
T1839 Mps1-IN-2 Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
T2039 GSK923295 GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
T2313 MPI0479605 MPI-0479605 is an ATP competitive and selective inhibitor.
T2689 AZ 3146 AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
T3118 Dimethylenastron Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
T3120 K858 K858 is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
T4048 Monastrol Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T6393 ARQ 621 ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
T4649 Monastrol Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM.
TQ0314 EMD534085 EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
T12434 PF-2771 PF-2771 is an inhibitor of centromere protein E (CENP-E)(IC50 of 16.1 nM).
T8487 Empesertib Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
T14765 BOS-172722 BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint. With an IC50 of 2 nM.
T14906 CCT251455 CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T11155 Eg5 Inhibitor V, trans-24 Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 agonist inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.
T11859L Litronesib Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
T16152 Betamethasone 17-benzoate Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).
T17007 TC-Mps1-12 TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
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