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Influenza Virus
T0104 Arbidol hydrochloride Arbidol (Umifenovir) hydrochloride, an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane.
T1486 Oseltamivir phosphate Oseltamivir Phosphate is the phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. By blocking neuraminidases on the surfaces of inf
T2522 Peramivir Trihydrate Peramivir is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are not released from infected cells. Peramivir
T2529 Zanamivir Zanamivir is a guanido-neuraminic acid that is used to inhibit NEURAMINIDASE.
T6642 Rimantadine Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
T4377 Pimodivir Pimodivir, an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit.
T5186 Oseltamivir acid Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.
T7330 Nucleozin Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
T7602 Theaflavin Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammatory, and antiviral p
T7785 T-1105 T-1105 is a broad-spectrum antiviral inhibitor.
T8263 3,4'-Dihydroxyflavone 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].
TN1066 Filixic acid ABA Filixic acid ABA exhibits inhibitory effects on neuraminidase of influenza virus H5N1 with IC50 as 29.57 ± 2.48 μM, it may have anti-influenza virus activity.
TN1506 Clemastanin B Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus at
TN1693 Glabrone Glabrone shows antiviral activity against influenza virus.
TN2176 Sanggenol A Sanggenol A shows neuroprotective activity on glutamate-induced cell death in HT22 cells, with EC50 values of 34.03 ± 7.71 μM. Sanggenol A inhibits influenza A viral and pneumoco
TN2231 Soyasaponin II Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
TN2331 Eleutheroside B1 Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza
T8354 Triazavirin Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T8502 N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibited the Ebola virus w
T8501 3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide 3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide with antiviral activity against Ebola virus that targets th
T8498 EiDD1931 EiDD1931 is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respir
T14495 Baloxavir Baloxavir is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
T12724 RIG-1 modulator 1 RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.
T12818 S119-8 RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorpora
T12953 Sodium copper chlorophyllin B Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV (IC50s of 50 to 100 μM).
T15770 LNK754 LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer's disease.
T4S1114 Dryocrassin ABBA Dryocrassin ABBA is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.
TN3461 Asebotin Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influ
TN4392 Koaburaside Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic infl
TN4716 Oplodiol Oplodiol exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strains. Oplodiol has a stimulative effect on significantly proliferation and differentiation of
TN4810 Platyphyllonol Platyphyllonol-5-xylopyranoside is moderately active against KBNP-0028 (H9N2) avian influenza virus as compared with zanamivir.
TN5005 Shegansu B Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells.
T13229 Tunicamycin Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibits gram-positive bac
T4027 KIN1148 KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection following viral infection
TN1103 Diphyllin Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
T8793 CBS1117 CBS1117 is a virus entry inhibitor (IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1)). It interferes with the hemagglutinin (HA)-mediated fusion process.
T15707 Laninamivir Laninamivir is an effective inhibitor of influenza neuraminidase (NA) (IC50s: 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p
T15707 Laninamivir Laninamivir is an effective inhibitor of influenza neuraminidase (NA) (IC50s: 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p
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