||TAPI-1 trifluoroacetate (171235-71-5(free base))
||TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
||WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is
||Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II.
||GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM).
||Benzyl cinnamate is a natural product isolated from various plant species,with anti-inflammatory activity.
||Meranzin exhibits strong anti-inflammatory and analgesic activity.
||Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema model in mice and rats
||Dehydrotumulosic acid shows anti-inflammatory activity.
||Arnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
||Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml
||1,3,6-Tri-O-galloylglucose shows anti-inflammatory activity.
||3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tum
||3-O-Acetyl-16 alpha-hydroxytrametenolic acid
||3-O-Acetyl-16 alpha -hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetrad
||Acanthoside has inhibitory effects on the allergic inflammation.
||Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats.
||Arjungenin shows α²-glucuronidase inhibitory activity, it shows antiviral, and anti-inflammatory activities.
||beta-Amyrin acetate has anti-inflammatory, antioxidant, and antidyslipidemic activities, it shows significant HMG-CoA-reductase and sEH inhibition.
||Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction.
||Dehydropachymic acid shows antiinflammatory activity.
||Dl-alpha-tocopheryl acetate is a dietary supplement.
||(-)-Epigallocatechin-3-(3''-O-methyl)gallate shows antioxidative, cytotoxic, antiallergic, and anti-inflammatory activities, it can negatively regulate basophil activation through
||Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.
||Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and heraclenin inhibit the
||Isolariciresinol has antioxidant and anti-inflammatory activities during an in vitro gastro-intestinal digestion of the Radix Isatidis extract (RIE).
||Kaempferol-3-O-α²-d-galactoside has antioxidant, anti-inflammatory and antinociceptive activities.
||Myricetin 3-O-beta-D-glucopyranoside may have antioxidant, and anti-inflammatory activities.
||Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation activity against rabbit
||Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 < or = 18.19 microM) of superoxide anion generation by human neutrophils in response to formyl- l-methi
||Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistres
||Isocolumbin has anti-inflammatory, and antimicrobial activities.
||Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus at
||Ganoderic acid C2
||Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Eps
||Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrog
||Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
||Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expre
||Mesaconine has cardiac effect, it also has anti-NF-κB activity. Mesaconine may be part of material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppressio
||Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
||Daphnetin 7-methyl ether
||Daphnetin 7-methyl ether has anti-inflammatory activity.
||11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and it
||8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, t
||Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA me
||Chasmanine, hypaconitine, and deoxyaconitine are anti-inflammatory pharmacodynamic components in Heishunpian (HSP) with positive relations with HSP efficacy. Chasmanine has insecti
||Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities.
||Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it h
||2'-Hydroxygenistein is an isoflavonoid phytoalexin, it suppresses chemical mediators in inflammatory cells, may have value in treatment and prevention of central and peripheral inf
||2-Oxopomolic acid shows cytotoxic activity, it shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. 2-Oxopomolic acid shows
||3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemoprev
||(+)-3-Hydroxy-1,5-diphenyl-1-pentanone exhibits both immunomodulatory and anti-tumor activity.
||3'-O-Methylmurraol may have potential anti-inflammatory activity, it exhibits inhibition (IC50 ≤ 7.31 ug/mL) of superoxide anion generation by human neutrophils in response to fo
||Alpinone 3-acetate has anti-inflammatory activity, it can inhibit 12-O-tetradecanoyiphorbol 13-acetate-induced inflammation in a mouse model of ear edema.
||Alternariol monomethyl ether
||Alternariol monomethyl ether,an Alternaria toxin, is a strong mutagen in Escherichia coli strain ND-160. Alternariol monomethyl ether has genotoxic properties, it can cause oxidati
||Arjunglucoside I has anti-inflammatory activity, it exhibits significant activity against carrageenan-induced paw edema in rat. It also shows antiproliferative activity against the
||Axillarin has antioxidant activity, it shows xanthine oxidase inhibitory activity ( IC(50) :36.0 uM). Axillarin can strongly protect primary cultured neurons against glutamate-indu
||Melongenamides B-D and Cannabisin F have anti-inflammatory activity, they exhibit inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages with IC
||Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC prolife
||Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first commit
||Delta 7-avenasterol has antioxidant activity.
||Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elasta
||Evofolin C and its acetate show strong antifungal and antibacterial activity. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide
||Ganoderic acid K
||Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.
||Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibition of cell migrati
||Hautriwaic acid shows anti-inflammatory activity in 12-O-tetradecanoylphorbol 13-acetate (TPA) mice ear edema models, it diminishes the joint edema induced by this mixture of polys
||Hedychenone has anti-inflammatory activity, it also shows potent in vitro cytotoxic activity against cancerous cells.
||Hispanone possesses anti-inflammatory activity, it shows inhibition of superoxide anion generation and elastase release.
||Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells.It also shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting activity in an in v
||Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils
||Lamiide has anti-inflammatory activity in carrageenin-induced paw edema test. It shows lipid peroxidation inhibition on rat-brain phospholipid peroxidation.
||Mannioside A has anti-inflammatory activity, inhibits carrageenan-induced paw edema in the rat.
||(+)-Matairesinol exhibits immunomodulatory activity; it also shows inhibition of the discoloration of yellowtail dark muscle.
||Methyl 3-carbazolecarboxylate is a natural product from Micromelum sp.
||Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elici
||Phyltetralin has antihyperuricemic activity.
||Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG
||Plumieride has plant growth inhibiting properties, it shows strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. Plumieride also has
||Procumbide has anti-inflammatory activity.
||Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora
||Ptaquiloside shows genotoxicity, it also has carcinogenic effects. Ptaquiloside has immunosuppressive effects, it reduces NK cell activities by enhancing metallothionein expression
||Rubelloside B exhibits immunological enhancement effect.
||Scoparinol has sedative, anti-inflammatory, analgesic, and diuretic actions.
||Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties.
||Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils.
||Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic cell line, KU812. Ta
||Tomentin has anti-inflammatory effects, it can inhibit the formation of Î»-carrageenan footpad edema at 58%.
||Triptobenzene H shows the significant immunosuppressive activity.
||Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; α
||Vasicinolone has anti-inflammatory, and antimicrobial activities.
||Vestitol has antioxidation, anti-inflammatory and antimicrobial activities, it can strongly act in a low dose and concentration and have a promising potential to be applied in the
||Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose
||Wittifuran X has antioxidant and anti-inflammatory activities.
||(-)-Zeylenol shows antifeedant activity. Zeylenol shows inhibitory activity toward the root growth of Lactuca sativa. Zeylenol probably possesses anti-inflammatory activity by inhi