Immunology & Inflammation related
||TAPI-1 trifluoroacetate (171235-71-5(free base))
||TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
||WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is
||Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II.