首页AutophagyHIV Protease
HIV Protease
T0100 Atazanavir sulfate Atazanavir sulfate is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with other ANTI-HIV AGENTS.
T0100L Atazanavir Atazanavir(BMS-232632) is an highly effective HIV-1 protease inhibitor.
T0110 Zalcitabine Zalcitabine(Dideoxycytidine;ddC; 2', 3'-Dideoxycytidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI); At low concentrations, It can potently inhibit HIV replicati
T1267 Abacavir Abacavir is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces
T1525 Ritonavir Ritonavir is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by bl
T1595 Nevirapine Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4
T1623 Lopinavir Lopinavir is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins th
T1815 Dapivirine Dapivirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.
T1883 Des(benzylpyridyl) Atazanavi The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.
T2239 Raltegravir potassium Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
T2324 Darunavir Darunavir is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administer
T2329 Dolutegravir sodium Dolutegravir sodium salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140
T2332 Elvitegravir Elvitegravir is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C
T2393 Efavirenz Efavirenz is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of efavirenz is as a Non-Nucleoside Reverse Transcripta
T2409L Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is
T2728 Limonin Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.
T2830 Betulinic acid Betulinic acid is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial,
T3172 Trovirdine Trovirdine is a thiourea non-nucleoside reverse transcriptase inhibitor.
T3335 Darunavir Ethanolate Darunavir ethanolate is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is
T3523 Fostemsavir BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.
T3632 Doravirine Doravirine is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.
T3683 lithospermic acid lithospermic acid is a potent anti-HIV agent and shows anti-gonadotrophic and anti-thyroidal effects.
T3732 Sebacic acid Sebacic acid is a saturated, straight-chain naturally occurring dicarboxylic acid.
T6001 Nelfinavir Mesylate Nelfinavir Mesylate is an effective HIV protease inhibitor (Ki: 2 nM).
T6065 Triciribine Triciribine is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.
T6098 Cabotegravir Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).
T6198 Dolutegravir Dolutegravir (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q14
T6367 Abacavir sulfate Abacavir, a nucleoside analogue, effectively utilize its antiviral activity
T6388 Amprenavir Amprenavir is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV) protease.
T6420 BMS707035 BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
T6653 Salmeterol Xinafoate Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary dis
T3S2007 MRE269 MRE-269 is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269 is used for the treatment of pulmonary arterial hypertension. MRE-269 is an active met
T4S0295 Apigenin 7-glucoside 1. Cosmosiin is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin recept
T2S0223 Isosinensetin 1. Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities.
T4493 Bictegravir Bictegravir is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).
TL0006 Chicoric Acid Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-
T4S1999 Valepotriate Valepotriate fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they a
T4962 Ginsenoside Z-R1 Zingibroside R1 has anti-HIV-1 activity.
T4S1718 Punicalin Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an
T5965 Ditiocarb sodium Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection.
T5863 Indinavir sulfate Indinavir is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
T7111 Tenofovir Disoproxil Tenofovir Disoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
T7282 Tenofovir alafenamide fumarate Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
T7212 Delavirdine (mesylate) Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
T5782 Bevirimat Bevirimat(PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.
T7382 NBD-557 NBD-557 is a potentially HIV-1 inhibitor.
T7455 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .
TQ0217 Gomisin G Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9.
TQ0297 Cenicriviroc Cenicriviroc is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory activity.
T7779 Nelfinavir Nelfinavir is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
T7789 DRB DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 µM)
T7903 Saquinavir Saquinavir is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.
T6256 YYA021 YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.
T4537 SodiumCholate SodiumCholate exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
T4S1383 Escin IA;Aescin IA Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action
T8156 Saquinavir mesylate Saquinavir mesylate is an  Inhibitor of HIV Proteaseused in antiretroviral therapy
T7700 Lersivirine(UK 453061) Lersivirine(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.
T8311 ABX-464 ABX-464 is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) (IC50 : 0.1 μM - 0.5 μM)
TN1194 16beta,17-Dihydroxy-ent-kaurane-19-oic acid 16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50 value of 0.8 microg
TN1235 3,4,5-Tricaffeoylquinic acid 3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α±- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor 4 expression
TN1348 8-Prenylluteone 8-Prenylluteone can potently inhibit HIV-1 PR activity.
TN1587 Dihydroseselin Dihydroseselin type of pyranocoumarin possessing a 4'-isovaleryl group is important to suksdorfin's enhanced anti-HIV activity.
TN1708 Gomisin M2 Gomisin M2 is an anti-HIV agent.
TN1727 Helichrysetin Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines
TN1767 Interiotherin A Interiotherin A inhibits HIV replication with the EC50 value of 3.1 micrograms/mL.
TN1852 Lancifodilactone F Lancifodilactone F exerts minimal cytotoxicity against C8166 cells (CC50 > 200 microg/mL) and shows anti-HIV activity with EC50 = 20.69 +/- 3.31 microg/mL and a selectivity index >
TN1866 Licoricesaponin G2 Licoricesaponin G2 has the anti-inflammatory effects as NF-κB inhibitors, it has anti-HIV activity via significantly interacted with R15K.
TN2097 Pomolic acid Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and de
TN2158 Robinetin Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.
TN2186 Schisantherin D Schisantherin D shows good anti-HIV activity with the EC50 value of 0.5 micrograms/mL, and the therapeutic index (TI) value of 110.
TN2283 Tripterifordin Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
TN2284 Triptonine B Triptonine B demonstrates potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000.
TN1047 Ingenol mebutate Ingenol mebutate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angel
TN1670 Ganodermanondiol Ganodermanondiol exhibits potent cytoprotective effects on t-BHP-induced hepatotoxicity in human liver-derived HepG2 cells, presumably through Nrf2-mediated antioxidant enzymes and
TN2231 Soyasaponin II Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
TN1302 6,8-Diprenylorobol 6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals.
T13796 Nigranoic acid Nigranoic acid is a natural product,and inhibits HIV-1 reverse transcriptase.
T12420L Pentosan Polysulfate Sodium Pentosan Polysulfate Sodium is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cystitis.
T12420 Pentosan Polysulfate Pentosan Polysulfate is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cystitis.
T10111 3-Deazaadenosine hydrochloride 3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.
T10928 Cytochalasin A Cytochalasin A is a cell-permeable fungal toxin and is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50 = 3 μM), inhibits actin pol
T10111L 3-Deazaadenosine 3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, and it has anti-inflammatory, anti-proliferative and anti-HIV activity.
T14208 AMD 3465 AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagoni
T14307 Aplaviroc Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
T14313 Apricitabine Apricitabine (SPD754; AVX754) shows promising antiretroviral efficacy, good tolerability and a low propensity for resistance selection in antiretroviral-naive HIV infection[2]. Apr
T14488 Azt-pmap Azt-pmap shows anti-HIV activity[1]. Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV inf
T14559 BI 224436 BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.
T12715 Reverse transcriptase-IN-1 Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor.
T14831 Bryostatin 1 Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and th
T15210 Elsulfavirine Elsulfavirine is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.
T15371 Gardiquimod Gardiquimod is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7. Gardiquimod could inhibit HIV-1 infection of macrophages and a
T12953 Sodium copper chlorophyllin B Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV (IC50s of 50 to 100 μM).
T11189 Emtricitabine S-oxide Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation
T10658 CA inhibitor 1 CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.
T10714 CCR5 antagonist 1 CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
T15683 L-689502 L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).
T10570 Fostemsavir Tris Fostemsavir Tris is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by bi
T10296 Mavorixafor trihydrochloride Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (
T16096 Filorexant Filorexant is an orally bioavailable effective and selective reversible OX1 and OX2 receptor antagonist (<3 nM in binding).
T16112 ML67-33 ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator of temperature- a
T16500 PF-3450074 PF-3450074 acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation s
T16548 PKF050-638 PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC50=0.04 μM).
T16555 PNU-103017 PNU-103017 is an inhibitor of HIV protease.
T16829 (S)-BI-1001 (S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
T16973 TAK-220 TAK-220 is a selective and orally bioavailable CCR5 antagonist (IC50s: 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively).
TP1809 TAT TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields
T2S0605 Liquidambaric lactone Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity.
TN2839 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid 2alpha,19alpha-Dihydroxy-3-oxo-urs-12-en-28-oic acid has anti-HIV activity. It shows an inhibitory effect on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by
TN3119 5-Hydroxy-7,8-dimethoxyflavanone 5-Hydroxy-7,8-dimethoxyflavanone shows anti-inflammatory activity, it can significantly decrease TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) s
TN3152 6-Acetonyldihydrochelerythrine 6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values
TN3444 Aristolactam BII Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinas
TN3567 Calanolide E Calanolide E2 has anti-HIV activity.
TN3704 Coronalolide Coronalolide shows significant cytotoxic activities in P-388 cell line, it also displays significant anti-HIV activities in the HIV-1RT assay. Coronalolide and coronalolide methyl
TN3705 Coronalolide methyl ester Coronalolide methyl ester displays significant anti-HIV activities in the HIV-1RT assay. It and coronalolide show broad cytotoxic activity against a panel of human cancer cell line
TN3777 Daurichromenic acid Daurichromenic acid is a terpenophenol with a potent anti-HIV activity.
TMA1012 Ganoderiol F Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with I
TN4109 Ganolucidic acid A Ganolucidic acid A exhibits cytotoxicity, has inhibitory activities against human HeLa cervical cancer cell lines. It shows significant anti-human immunodeficiency virus (anti-HIV)
TN4264 Isoapetalic acid Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gra
TN4347 Jacoumaric acid Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor.
TN4433 Licoarylcoumarin Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-
TN4539 Methyl chanofruticosinate Methyl chanofruticosinate has weak anti-HIV-1 activity.
TN4555 Methyl salvionolate A Methyl salvionolate A has anti-HIV-1 activity.
TN4584 Morolic acid Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, chole
TN4585 Moronic acid Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified t
TN4605 Myriceric acid B Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radica
TN4646 Neotripterifordin Neotripterifordin shows potent anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 25 nM and TI of 125.
TN4673 (+)-Nortrachelogenin (+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 +/- 1.8 microM. (+)-
TN4675 Nortrachelogenin Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors, t
TN4820 Pre-schisanartanin B Pre-schisanartanin B has cytotoxicity, it also has anti-HIV-1 activity.
TN4835 Przewalskin Przewalskin A and Przewalskin B showed modest anti-HIV-1 activity with EC50 = 41 and 30 microg/mL, respectively.
TN4911 Rhuscholide A Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40.
TN4934 Salaspermic acid Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
TN5011 Shizukaol B Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by
TN5012 Shizukaol C 1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxicities against C8166 c
TN5133 3',5,5',7-Tetrahydroxy-4',6-dimethoxyflavone 5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably a
TN5177 Trigothysoid N Trigothysoid N may have anti-HIV activity.
TN5191 Tsugafolin Tsugafolin has weak anti-HIV activity.
TN5243 Vitexilactone Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has tr
TN5263 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic effects, the productio
T8238 Fosamprenavir Calcium Salt Fosamprenavir Calcium Salt (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
T8689 CHLOROQUINE Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthrit
TP1348 FC131 TFA FC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
T15436 GSK2838232 GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.
T13647 Dextran sulfate sodium salt (MW 16000-24000) Dextran sulfate sodium salt (MW 16000-24000) is an anhydrous glucose polymer with a molecular weight range of 16000-24000. The sodium salt inhibits the replication of the human imm
T4182 lavendustin B Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p
T16764 RN-18 RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).
TN1103 Diphyllin Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
T4665 BMS626529 BMS-626529 is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
T3321 Oleanonic Acid Oleanolic acid is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties.
T11451 GPI-1046 GPI-1046 is an immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core.
  • 关注公众号
    - 超值特惠
    - 客户福利
    - 业界动态
    - 实用攻略
陶素的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)。