Glucocorticoid Receptor

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T0034	Cortisone acetate	Cortisone Acetate is the acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with an
T0034	Cortisone acetate	Cortisone Acetate is the acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with an
T0083	Eplerenone	Eplerenone is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevation
T0094	Budesonide	Budesonide, an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensi
T0107	Halcinonide	Halcinonide, a high-efficiency corticosteroid, is served as an anti-inflammatory agent used in topical preparations.
T0181	Loteprednol etabonate	Loteprednol Etabonate is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.
T0188	Fluticasone propionate	Fluticasone propionate, derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
T0208	Prednisolone phosphate sodium	Prednisolone disodium phosphate, a synthetic glucocorticoid, has immunomodulating and anti-inflammatory properties.
T0261	Amcinonide	Amcinonide is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
T0270	Hydrocortisone butyrate	Hydrocortisone Butyrate is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
T0337	Prednisolone-21-acetate	Prednisolone Acetate is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T0343	Nimodipine	Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
T0354	Canrenone	Canrenone is an aldosterone antagonist with potassium-sparing diuretic activity.
T0367	Fluocinolone acetonide	Fluocinolone acetonide is a glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has
T0485	Deflazacort	Deflazacort is a glucocorticoid served as an immunosuppressant and anti-inflammatory. It can be used to treat autoimmune diseases due to inhibiting the immune system. It can also b
T0798	Triamcinolone	Triamcinolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid rec
T0820	Triamcinolone acetonide	Triamcinolone acetonide is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocor
T0947	Dexamethason acetate	Dexamethasone Acetate is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuc
T0948L	Corticosterone	Corticosterone is a sensitive inhibitor of monoamine transport.
T0977	Medrysone	Medrysone is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellu
T1018	Prednisone	Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T1076	Dexamethasone	Dexamethasone is a glucocorticoid receptor agonist and an IL receptor modulator.Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccha
T1102	Mifepristone	Mifepristone is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.
T1124	Flumethasone	Flumethasone is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
T1127	Beclomethasone dipropionate	Beclomethasone Dipropionate is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment a
T1163	Betamethasone 17-valerate	Betamethasone Valerate is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.
T1168	Desonide	Desonide is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor c
T1171	Methylprednisolone	Methylprednisolone is a PREDNISOLONE derivative with similar anti-inflammatory action.
T1243	Hydrocortisone acetate	Hydrocortisone acetate is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.
T1284	Megestrol acetate	Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mout
T14301	Apararenone	Apararenone is a novel antagonist of non-steroidal mineralocorticoid receptor, and for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.
T15246	Esaxerenone	Esaxerenone is a highly potent and selective non-steroidal antagonist of the mineralocorticoid receptor.
T1531	Mometasone furoate	Mometasone furoate is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used a
T15389L	Glucagon hydrochloride (16941-32-5 free base)	Glucagon hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon hydrochloride stimulates gluconeoge
T15389L	Glucagon hydrochloride (16941-32-5 free base)	Glucagon hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon hydrochloride stimulates gluconeoge
T1541	Drospirenone	Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.
T15451	GW-870086	GW-870086 is an effective anti-inflammatory agent. GW-870086 also plays a role in a glucocorticoid receptor agonist (pIC50: 10.1 in A549 cells expressing NF-κB).
T1559	Betamethasone dipropionate	Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethas
T1560	Prednisolone	Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T1561	Clobetasol propionate	Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results
T1573	Flunisolide	Flunisolide is a synthetic corticosteroid with anti-inflammatory and antiallergic properties.
T1614	Hydrocortisone	Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inf
T1652	Betamethasone	Betamethasone, a glucocorticoid steroid, has immunosuppressive and anti-inflammatory properties.
T1666	Fludrocortisone acetate	Fludrocortisone, a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-resp
T16727	Relacorilant	Relacorilant is a selective and orally bioavailable antagonist of glucocorticoid receptor(Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and
T16727	Relacorilant	Relacorilant is a selective and orally bioavailable antagonist of glucocorticoid receptor(Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and
T16727	Relacorilant	Relacorilant is a selective and orally bioavailable antagonist of glucocorticoid receptor(Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and
T1749	AL082D06	AL 082D06(D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR(Ki > 10 uM).
T21395	Finerenone	Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart fai
T2526	Ciclesonide	Ciclesonide(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.
T2548	Diflorasone	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the c
T2748	Cortodoxone	Cortodoxone is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland.
T2810	(20S)-Protopanaxatriol	(20S)-Protopanaxatriol(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor.
T2884	Cortisone	Cortisone is a corticosteroid with potent glucocorticoid activity.
T3096	Potassium canrenoate	Potassium canrenoate is a synthetic pregnadiene derivative with anti-aldosterone activity.
T3316	Fluoromethalone	Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone a
T3962	TPI1	TPI-1 is a SHP-1 inhibitor.
T4602	Hydrocortisone 21-hemisuccinate	Hydrocortisone 21-hemisuccinate is a corticosteroid used as an analytical and chromatography reagent.
T6022	LY404039	LY404039 is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
T6502	Fluocinonide	Fluocinonide (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.
T6503	Fluorometholone Acetate	Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
T6580	Meprednisone	Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
T8396	Prednisone acetate	Prednisone acetate is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory.
T8777	BecloMethasone	BecloMethasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.
TQ0225	AZD7594	AZD7594 is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).