Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T11468 | GSK-3 inhibitor 1
化合物 T11468
|
603272-51-1 |
|
|
GSK-3 inhibitor 1 is a GSK-3 inhibitor. | ||||
T79693 | PIMPC
化合物 PIMPC
|
2250244-44-9 | 98% |
|
PIMPC为具抗氧化及金属螯合性能之化合物,新型糖原合成酶激酶3(GSK-3)抑制剂,潜在抗阿尔茨海默病作用。 | ||||
T80124 | C-Peptide 1 (rat)
化合物 C-Peptide 1 (rat)
|
41475-27-8 | 98% |
|
C-Peptide 1 (rat) 为肽类化合物,作为β-catenin/GSK-3β激活剂,具有调节Wnt/β-catenin信号通路的功能,常用于癌症研究领域。 | ||||
T82243 | HAChE-IN-5
化合物 hAChE-IN-5
|
98% |
|
|
hAChE-IN-5(化合物49)是一种同时针对hAChE和hBuChE的有效抑制剂,其IC50值均为0.17 μM。此外,hAChE-IN-5对GSK3β同样展现出良好的抑制活性,IC50值为0.21 μM。作为tau蛋白聚集和Aβ1-42自聚集的抑制剂,hAChE-IN-5能够结合PAS,进而阻止Aβ依赖的神经毒性。... | ||||
TN4263 | Isoangustone A
化合物 TN4263
|
129280-34-8 | 98% |
|
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation ... | ||||
TN3319 | 9-Hydroxycanthin-6-one
化合物 TN3319
|
138544-91-9 | 98% |
|
9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ... | ||||
T10172 | 5-Iodo-indirubin-3'-monoxime
5-碘靛红-3'-单肟
|
331467-03-9 | 98% |
|
5-Iodo-indirubin-3'-monoxime 是一种 GSK-3β、CDK5/P25和CDK1/cyclin B 抑制剂,IC50值分别为 9、20 和 25 nM,与 ATP 竞争性地结合酶的催化位点。 | ||||
T2S0606 | Bakkenolide A
蜂斗菜内酯A
|
19906-72-0 | 98% |
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign... | ||||
T10786 | Charantin
化合物 T10786
|
57126-62-2 | 98% |
|
Charantin is a steroidal saponin isolated from Momordica charantia. It increases the release of insulin and slowing down gluconeogenesis. Charantin can inhibit G... | ||||
TN4637 | Neogrifolin
化合物 TN4637
|
23665-96-5 | 98% |
|
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS ... | ||||
TN2995 | 4,10-Aromadendranediol
化合物 TN2995
|
70051-38-6 | 98% |
|
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which may be beneficial to the treatm... | ||||
TN2775 | 2-Methoxystypandrone
化合物 TN2775
|
85122-21-0 | 98% |
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm... | ||||
TMA0291 | Dehydroglyasperin D
化合物 TMA0291
|
517885-72-2 | 98% |
|
Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29 h... | ||||
TN4046 | Excisanin A
化合物 TN4046
|
78536-37-5 | 98% |
|
ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a pote... | ||||
T35556 | GSK-3β inhibitor 8
GSK-3β抑制剂8
|
1139875-74-3 | 98% |
|
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII)是具有有效和选择性的 GSK-3β 抑制剂 ,IC50值为 64 nM。GSK-3β inhibitor 8 是一种噻吩嘧啶衍生物,负调控 Wnt 信号通路,刺激 β 细胞增殖。 | ||||
T11960 | MBM-55
化合物MBM-55
|
2083622-09-5 | 99.98% |
|
MBM-55 是一种有效的中心体相关激酶 2 (NEK2) 抑制剂,IC50 为 1 nM。 MBM-55 通过诱导细胞周期停滞和凋亡有效抑制癌细胞的增殖。 | ||||
T1260 | Cromolyn sodium
色甘酸钠
|
15826-37-6 | 99.95% |
|
Cromolyn sodium (FPL-670) 是一种GSK-3β抑制剂,IC50为 2.0 µM,有抗过敏作用。 | ||||
T1881 | AR-A014418
化合物AR-A014418
|
487021-52-3 | 99.94% |
|
AR-A014418 (GSK 3β inhibitor VIII) 是选择性的,ATP 竞争性的 GSK3β抑制剂 ,其 IC50=104 nM,Ki=38 nM。 | ||||
T6940 | PHA-767491 hydrochloride
化合物PHA767491 HCl
|
942425-68-5 | 99.92% |
|
PHA-767491 hydrochloride (CAY-10572 hydrochloride) 是一种Cdc7-Dbf4(DDK)/Cdk9的双重抑制剂,IC50值分别为 10 nM 和 34 nM。 | ||||
T1965 | Bikinin
化合物Bikinin
|
188011-69-0 | 99.91% |
|
Bikinin (Abrasin) 是一种非甾体类的,ATP 竞争性的,植物性 GSK-3/Shaggy-like kinases 抑制剂,可激活 BR 信号通路。 |