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GPCR19
T11662L INT-777 INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).
T1824 TGR5 Receptor Agonist TGR5 is a potent TGR5(GPCR19) agonist.
T2965 Deoxycholic acid Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats f
T2968 Hyodeoxycholic acid Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
T4083 BAR 501 BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
T4352 SB756050 SB756050 is a specific TGR5 agonist.
T5077 Sodium Desoxycholate Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
T5100 DJ-V159 DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).
T7428 SBI-115 SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
T8752 BAR 501 impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 µM)
T8752 BAR 501 impurity BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 µM)
T8818 TC-G 1005 TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose
TQ0252 BAR502 BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
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