||TGR5 Receptor Agonist
||TGR5 is a potent TGR5(GPCR19) agonist.
||BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM).
||SB756050 is a specific TGR5 agonist.
||DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).
||Sodium Desoxycholate can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
||SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5
||BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
||Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
||INT-777 is a potent agonist of TGR5 (EC50: 0.82 μM).