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Ferroptosis
T1637 Deferoxamine Mesylate Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
T1765 Erastin Erastin is a ferroptosis activator acting on mitochondrial VDAC. It induces ferroptotic cell death in vitro.
T2376 Liproxstatin-1 Liproxstatin-1 is a potent ferroptosis inhibitor.
T5343 UAMC-3203 UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
T5523 Imidazole ketone erastin Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.
T6500 Ferrostatin-1 Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).
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