||Erastin is a ferroptosis activator acting on mitochondrial VDAC. It induces ferroptotic cell death in vitro.
||Liproxstatin-1 is a potent ferroptosis inhibitor.
||Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).
||Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis.
||UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
||Imidazole ketone erastin
||Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.
||UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
||iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3.iFSP1 is a potent, selective and glutathione-independent inhibitor