首页AutophagyEndogenous Metabolite
Endogenous Metabolite
T7571 1-Methyladenosine 1-Methyladenosine (M1A) belongs to the class of organic compounds known as purine nucleosides.
TP1087 Substance P Substance P (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family.
TP1277 Bradykinin Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpo
TP1442 Neuromedin B Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous
T8547 DCBA DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET.
T14063 7α,25-Dihydroxycholesterol 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve
Fr13756 Isonicotinic acid Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biot
T14128 Adenosylcobalamin Adenosylcobalamin is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corr
T13265 Urolithin B Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphoryl
T1311 4-aminobenzoic acid 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.
T12296 Oleoylethanolamide Oleoylethanolamide is a high affinity endogenous agonist of PPAR-α.
T10857 Coenzyme A Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.
T0925 Allantoin Allantoin, a urea hydantoin found in urine and plants, is used in dermatological preparations.
T0887 D(+)-Glucose D(+)-Glucose is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeuti
T0591 Alpha-D-galactose D-Galactose is an aldohexose that exists naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metaboli
T0583 Erythritol Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
T0529 Dulcitol Dulcitol is a sugar alcohol that is a metabolic breakdown product of galactose.
T0496 Creatinine Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
Fr16745 4-Hydroxyphenylacetonitrile 4-Hydroxyphenylacetonitrile shows strong antioxidative activity.
Fr14438 p-Toluic Acid p-Toluic Acid belongs to the class of organic compounds known as benzoic acids. 4-Methylbenzoic acid has been primarily detected in saliva. Within the cell, 4-methylbenzoic acid i
T4525 Citraconic acid Citraconic acid is a dicarboxylic acid consisting of maleic acid having a methyl substituent at the 2-position.
T4120 N,N-Dimethylglycine N, N-Dimethylglycine is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also emp
T3007 Spermine Spermine is a biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.
T2O2730 serine Serine is a non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for
T2O2721 cysteine Cysteine is a naturally occurring, sulfur-containing amino acid which is important for protein synthesis, detoxification, and also exerts diverse metabolic functions.
T2O2683 proline 1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline catalysed aldol cond
T2A2497 glutamic acid (S)-Glutamic acid acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
T2A2476 L-Hydroxyprolin L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
T2971 Phytic acid Fytic acid is a complexing agent for removal of traces of heavy metal ions. It acts also as a hypocalcemic agent.
T2965 Deoxycholic acid Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats f
T2963 Cholic Acid Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
T2934 Bilirubin Bilirubin is a principal pigment of bile and one of the major end products of hemoglobin decomposition.
T2908 Palmitic acid Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
T2807 Caffeic Acid Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
T2796 Coenzyme Q10 Coenzyme Q10 (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T2719 Succinic acid Succinic acid is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters
T20446 Creosol Creosol is an agent of Antioxidant and Antibacterial.
T20257 Methyl 4-anisate Methyl anisate is an endogenous metabolite.
T19350 H-Val-Ala-OH H-Val-Ala-OH is a dipeptide formed from L-Valine and L-Alanine residues. It has a role as a metabolite. H-Val-Ala-OH is a dipeptide formed from L-Valine and L-Alanine residues.
T19344 Glycogen Glycogen is a glycolytic intermediate and high-energy phosphate that ACTS as a form of energy storage for humans, animals, fungi and bacteria.
T19180 Adrenic Acid Adrenic acid is a member of the class of compounds known as very-long-chain fatty acids. Adrenic acid can be found in blood and in human myelin tissue.
T19160 7,8-Dihydro-L-biopterin 7,8-Dihydro-L-biopterin is an oxidation product of tetrahydrobiopterin.
T1723 ADP Adenosine 5′-diphosphate induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.
T1705 4-Amino-5-imidazolecarboxamide An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation o
TJO2691 L-(-)-Fucose 1. Anti-infective, anti-cancer, enhance immunity 2. Skin moisturizing and delaying skin aging 3. Nutritional supplement
T8811 Tuftsin 3TFA Tuftsin 3TFA is a tetrapeptide. It is a macrophage/microglial activator.
T8783 4-Methylbiphenyl 4-Methylbiphenyl is an endogenous metabolite.
T8790 1-Methylhistamine dihydrochloride 1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of hi
T8789 N-Acetyl-L-tryptophan N-Acetyl-L-tryptophan is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
T8392 L(+)-Asparagine monohydrate L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function.
T8274 3-Methyl-L-histidine 3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof
T8271 10Z-Nonadecenoic acid 10Z-Nonadecenoic acid is a kind of long-chain fatty acid with anti-tumor activity.
T8264 3-Methyl-2-oxovaleric acid 3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxovaleric acid is a neurotoxin, an acidoge
T8227 5'-Methylthioadenosine 5'-Methylthioadenosine is produced from S-adenosylmethionine and behaves as a powful inhibitory product.
T8150 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
T8105 Indole-3-carboxaldehyde 1H-Indole-3-carboxaldehyde, also known as 3-formylindole or 3-indolealdehyde, belongs to the class of organic compounds known as indoles. Indoles are compounds containing an indole
T8094 16-Dehydroprogesterone 16-Dehydroprogesterone is a steroidal progestin.
T8075 1,3-Dimethyluric acid 1,3-Dimethyluric acid is a product of theophylline metabolism in man. It is one of the purine components in urinary calculi.
T8053 Ac-Arg-OH N-a-Acetyl-L-arginine, also known as N-ac-L-arg-OH or N-alpha-acetylarginine, belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated al
T8043 5α-Cholestane 5α-Cholestane belongs to the class of organic compounds known as cholestane steroids.
T8037 H-Phe-Phe-OH H-Phe-Phe-OH is a peptide made of two phenylalanine molecules; Phenylalanine is an essential amino acid and the precursor for the amino acid tyrosine.
T8026 (S)-(−)-Limonene (S)-(−)-Limonene is a Monoterpenoids,it can induce a mild bronchoconstrictive effect.
T7868 Farnesol Farnesol is a natural product, has the activity in inhibiting bacteria.
T7773 DPPC DPPC is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.
T7682 Asymmetric dimethylarginine Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T7665 [Leu5]-Enkephalin TFA(58822-25-6(free bas)) [Leu5]-Enkephalin is the most potent δ-receptor ago
T7647 Eicosadienoic acid Eicosadienoic acid is a rare, naturally occurring n-6 polyunsaturated fatty acid found mainly in animal tissues.
T7646 Alloepipregnanolone Alloepipregnanolone is a pregnane with anesthetic, hypnotic, and sedative properties.
T7641 5-Hydroxytryptophol 5-Hydroxytryptophol is a metabolite of tryptophan. It is used as a biomarker for recent alcohol consumption and causes sleeping sickness
T7634 3-Hydroxymandelic Acid 3-Hydroxymandelic Acid is a metabolite of Phenylephrine.
T7628 3b-Hydroxy-5-cholenoic acid 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin
T7606 Guanosine 5'-diphosphate disodium salt Guanosine 5'-diphosphate disodium salt is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleuki
T7595 L-DAB HBR L-DAB HBR is an inhibitor of GABA transaminase  (IC50 > 500 μM).
T7565 3-Hydroxycapric acid 3-hydroxydecanoic acid is a medium-chain fatty acid. It has a role as an antimitotic and an Escherichia coli metabolite.
T7520 Deoxycytidine triphosphate Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthes
T7511 Cyclo(his-pro) Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway.
T7508 N-Acetylputrescine hydrochloride N-Acetylputrescine is a polyamine commonly occurring excreted in normal human urine
T7458 5-Phenylvaleric Acid 5-Phenylvaleric acid is a pentanoic acid of bacterial origin, occasionally found in human biofluids.
T7457 5-Methyl-2'-deoxycytidine 5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.
T7408 all-trans-4-Oxoretinoic acid All-trans-4-Oxoretinoic acid is an active metabolite of vitamin A.
T7357 (S)-b-aminoisobutyric acid (S)-b-aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine.
T7344 SDMA SDMA is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).
T7335 L-2,3-Diaminopropionic acid L-2,3-diaminopropionic acid is an amino acid that is a precursor of antibiotics and staphyloferrin B a siderophore produced by Staphylococcus aureus.
T7331 Ursocholic acid Ursocholic acid, a bile acid found predominantly in bile of mammals.
T7210 Guanosine 5'-diphosphate Guanosine 5'-diphosphate as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T7154 trans-trans-Muconic acid trans-trans-Muconic acid is a urinary metabolite of benzene.
T7095 Hexacosanoic acid Hexacosanoic acid, a very long-chain fatty acid, is related to adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
T7094 Levomefolic Acid Levomefolinic acid is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functi
T6S0232 Eriodictyol 1. Eriodictyol is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving
T6523 Guanosine Guanosine is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism.
T6060 (±) Anabasine (±) Anabasine is a biphasic muscle relaxant.
T6000 D-DELTA-TOCOPHEROL D-DELTA-TOCOPHEROL is an isomer of Vitamin E,has antioxidant activity,and might be useful as effective ingredients in whitening cosmetics with lower skin toxicity.
T5986 3-Hydroxypicolinic acid 3-Hydroxypicolinic acid is a picolinic acid derivative, and belongs to the pyridine family.
T5984 Indole-3-carboxylic acid Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite .
T5982 3-Methoxybenzoic acid 3-methoxybenzoic acid is a food additive,and has antibacterial activity.
T5980 2-Ketoglutaric acid 2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
T5968 DL-Homocysteinethiolactone hydrochloride DL-Homocysteinethiolactone hydrochloride is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing oxid
T5915 D-chiro-Inositol D-chiro-Inositol is an epimer of myo-inositol that is found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bi
T5912 5-Methylcytidine 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.
T5891 D-ERYTHRO-SPHINGOSINE D-erythro-Sphingosine is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
T5890 2,4-Dihydroxybenzoic acid 2,4-Dihydroxybenzoic acid is found in alcoholic beverages.2, 4-Dihydroxybenzoic acid is a food flavour ingredient and flavour modifie.
T5875 4-Methoxycinnamic acid 4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissi.
T5874 2-Methoxybenzoic acid 2-Methoxybenzoic acid is a novel antiemetic which prevents nausea and vomiting in humans.
T5873 2,6-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.
T5646 Cinnamic acid Cinnamic acid has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, pro
T5589 H-Gly-Pro-OH H-Gly-Pro-OH is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism
T5583 D-(+)-Turanose D(+)-Turanose is a naturally occuring compound. It is a reducing disaccharide.
T5573 Coenzyme Q9 Coenzyme Q9 (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.
T5569 3-Amino-4-methylpentanoic acid Beta-leucine is a beta-amino acid that is pentanoic acid substituted at positions 3 and 4 by amino and methyl groups respectively. It has a role as a human metabolite.
T5568 H-Tyr(3-I)-OH H-Tyr(3-I)-OH is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones
T5557 Propylparaben Propylparaben is an antimicrobial agent, preservative, flavouring agent
T5556 5a-Pregnane-3,20-dione 5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone
T5089 5-Aminovaleric acid 5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is forme
T5014 Prostaglandin E2 (PGE2) Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constricti
T4S2157 Campesterol Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti
T4973 1,7-DIMETHYLXANTHINE Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Para
T4973 1,7-DIMETHYLXANTHINE Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Para
T4972 2'-Deoxycytidine-5'-diphosphate trisodium 2′-Deoxycytidine 5′-diphosphate (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and revers
T4972 2'-Deoxycytidine-5'-diphosphate trisodium 2′-Deoxycytidine 5′-diphosphate (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and revers
T4971 5'-DEOXYADENOSINE 5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genet
T4970 LANOSTEROL Lanosterol is a tetracyclic triterpenoid which is the compound from which all steroids are derived.
T4969 Guanosine 5'-triphosphate trisodium salt Guanosine 5'-triphosphate trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and
T4947 3-Hydroxybutyric acid 3-Hydroxybutyric acid (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised
T4945 DL-Normetanephrine hydrochloride rac-Normetanephrine Hydrochloride is a metabolite of Epinephrine. It is found together with Metanephrine in urine and in certain tissues.
T4944 Nervonic acid Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enha
T4944 Nervonic acid Nervonic acid is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enha
T4934 1-Methyl-L-histidine Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
T4933 Nα-Acetyl-L-asparagine N-Acetylasparagine, also known as acasn, belongs to the class of organic compounds known as asparagine and derivatives.
T4928 L-Kynurenine L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor im
T4927 4-Guanidinobutyric acid 4-Guanidinobutyric acid is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid
T4927 4-Guanidinobutyric acid 4-Guanidinobutyric acid is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been specifically use to human proton coupled amino acid
T4923 7-Dehydrocholesterol 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
T4923 7-Dehydrocholesterol 7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts.
T4921 Oxoadipic acid Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research o
T4921 Oxoadipic acid Oxoadipic acid is a key metabolite of the essential amino acids tryptophan and lysine.Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research o
T4919 3-Ureidopropionic acid Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. I
T4919 3-Ureidopropionic acid Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. I
T4917 (L)-Dehydroascorbic acid L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotect
T4917 (L)-Dehydroascorbic acid L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotect
T4907 3,4-Dihydroxyphenylacetic acid 3,4-Dihydroxybenzeneacetic acid is the main neuronal metabolite of dopamine.
T4899 L-Histidinol dihydrochloride L-Histidinol dihydrochloride is a precursor of histamine and a reversible inhibitor of protein synthesis.
T4895 Cadaverine dihydrochloride Cadaverine dihydrochloride, dihydrochloride salt of cadaverine (a diamine), is a biogenic amine
T4894 L-(-)-Arabitol L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose
T4893 Spermidine Spermidine inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4)
T4893 Spermidine Spermidine inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4)
T4892 3-(2-Hydroxyphenyl)propionic acid 3-(2-Hydroxyphenyl)propanoic acid, also known as melilotic acid or melilotate. Within the cell, 3-(2-hydroxyphenyl)propanoic acid is primarily located in the cytoplasm. 3-(2-Hydrox
T4890 3-Nitro-L-tyrosine 3-Nitrotyrosine is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitri
T4890 3-Nitro-L-tyrosine 3-Nitrotyrosine is the major product from the spontaneous reaction of peroxynitrite with tyrosine. Formation of nitrotyrosine can indicate the formation of peroxynitrite by a nitri
T4887 DL-3-AMINOISOBUTYRIC ACID beta-aminoisobutyric acid is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC 3.5.1.6), the last step in pyrimidine d
T4886 Dihydrouracil 5,6-Dihydrouracil is an intermediate breakdown product of uracil.
T4886 Dihydrouracil 5,6-Dihydrouracil is an intermediate breakdown product of uracil.
T4883 Creatine Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the
T4883 Creatine Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the
T4877 L-Homocystine Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Increa
T4874 Thiamine pyrophosphate Thiamine pyrophosphate is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biolo
T4874 Thiamine pyrophosphate Thiamine pyrophosphate is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biolo
T4873 2-Amino-1-phenylethanol 2-Hydroxyphenethylamine has been found in human testicle tissue, and has also been primarily detected in blood. 2-Hydroxyphenethylamine can be converted into 2-(hydroxymethyl)-4-(1
T4872 Palmitoleic acid Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.
T4870 Petroselinic acid Petroselinic acid is a monounsaturated omega-12 fatty acid found naturally in plant and animal oils and fats.
T4867 Erucic acid Increased levels of erucic acid (22:1n9) have been found in the red blood cell membranes of autistic subjects with developmental regression (PMID: 16581239 ). Erucic acid is broken
T4863 DL-Homocysteine DL-Homocysteine is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.
T4863 DL-Homocysteine DL-Homocysteine is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.
T4862 Oxaloacetic acid Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate
T4861 trans-Aconitic acid Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic
T4856 Nα-Acetyl-L-lysine N-Alpha-acetyllysine is a N-acetylated amino acid. It is a normal constituent of human urine with concentrations in normal samples too small to allow its routine detection; however
T4855 Tricosanoic acid Tricosylic acid, also known as N-tricosanoate or tricosylate, belongs to the class of organic compounds known as very long-chain fatty acids.Tricosylic acid has been detected in mu
T4852 Glyceryl trimyristate Within the cell, glyceryl trimyristate is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast
T4850 2-Picolinic acid PCL 016 is a topical antiviral agent, which inhibits adenovirus replication in rabbit.
T4848 DL-Mandelic acid It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabo
T4845 L-Lactic acid Lactic acid is an organic acid. It is a chiral molecule, consisting of two optical isomers, L-lactic acid and D-lactic acid, with the L-isomer being the most common in living organ
T4844 L-Methionine L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
T4839 N-Acetyl-L-alanine N-Acetyl-L-alanine is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4
T4838 L-(-)-Malic acid Malic acid is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple.
T4838 L-(-)-Malic acid Malic acid is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple.
T4837 Itaconic acid Itaconic acid, also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid ex
T4837 Itaconic acid Itaconic acid, also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid ex
T4832 Cytosine Cytosine is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucle
T4832 Cytosine Cytosine is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucle
T4825 D(+)-Xylose Xylose or wood sugar is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucr
T4825 D(+)-Xylose Xylose or wood sugar is an aldopentose - a monosaccharide containing five carbon atoms and an aldehyde functional group. It has chemical formula C5H10O5 and is 40% as sweet as sucr
T4813 L-Citrulline L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
T4812 D-Mannose D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylation of specific proteins.
T4794 Glutaric acid Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryp
T4780 Quinaldic acid Quinaldic acid, also known as quinaldate or chinaldinsaeure, belongs to the class of organic compounds known as quinoline carboxylic acids.
T4776 Glycerol Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and
T4768 Diethyl oxalpropionate Diethyl oxalpropionate, also known as methyloxalacetic acid diethyl ester or diethyl methyloxalacetate, is a member of the class of compounds known as beta-keto acids and derivativ
T4768 Diethyl oxalpropionate Diethyl oxalpropionate, also known as methyloxalacetic acid diethyl ester or diethyl methyloxalacetate, is a member of the class of compounds known as beta-keto acids and derivativ
T4767 Formamide Formamide is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been expo
T4767 Formamide Formamide is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been expo
T4766 3-Methylglutaric acid Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PM
T4765 L-Norleucine L-Norleucine is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
T4762 L-Pipecolic acid L-Pipecolic acid is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adreno
T4758 2'-Deoxycytidine monohydrate One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phospha
T4758 2'-Deoxycytidine monohydrate One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phospha
T4757 L-Homoserine Homoserine is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer to
T4749 Squalene Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil, though there are botanical sources as well, including rice bran,
T4740 Elaidic acid Elaidic acid is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated w
T4729 Phosphonoacetic acid Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is pr
T4728 4-ACETAMIDOBUTYRIC ACID 4-Acetamidobutanoic acid can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to huma
T4725 N-Acetyl-D-mannosamine N-Acetylmannosamine is a monosaccharide that is used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. N-Acetyl-
T4723 D-(-)-Tagatose D-Tagatose, a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods
T4716 Pyrrole-2-carboxylic acid Pyrrole-2-carboxylic acid was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino
T4713 Phosphocholine chloride calcium salt tet Phosphorylcholine is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the concentration of phosphorylcholine as the
T4707 3-Hydroxyanthranilic acid 3-Hydroxyanthranilic acid, also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthrani
T4707 3-Hydroxyanthranilic acid 3-Hydroxyanthranilic acid, also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthrani
T4702 (3-Carboxypropyl)trimethylammonium chlor (3-Carboxypropyl)trimethylammonium chloride is a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2
T4685 INOSINIC ACID Inosinic acid is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and
T4588 Glycochenodeoxycholic Acid Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolit
T4514 N-Acetyl-D-Glucosamine N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-trans
T3763 Fumaric acid Fumaric acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as a
T3735 Tetrahydro Curcumin Tetrahydrocurcumin, a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.
T3735 Tetrahydro Curcumin Tetrahydrocurcumin, a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.
T2O2774 L-Asparagine L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONI
T2O2774 L-Asparagine L-asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONI
T2O2728 glycine Glycine is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
T2O2728 glycine Glycine is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
T21629 Loxapine Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug
T19418 Methionine sulfoxide Methionine sulfoxide can be regarded as a biomarker of oxidative stress in vivo. Methionine sulfoxide is an oxidation product of methionine with reactive oxygen species.
T19418 Methionine sulfoxide Methionine sulfoxide can be regarded as a biomarker of oxidative stress in vivo. Methionine sulfoxide is an oxidation product of methionine with reactive oxygen species.
T19418 Methionine sulfoxide Methionine sulfoxide can be regarded as a biomarker of oxidative stress in vivo. Methionine sulfoxide is an oxidation product of methionine with reactive oxygen species.
T16674 Pseudouridine Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.
T16338 Norgestimate metabolite Norelgestromin Norelgestromin is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl estradiol.
TQ0285 Spaglumic acid Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.
TQ0265 Indolelactic acid Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.
TQ0265 Indolelactic acid Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.
TP1266 γ-Glu-Phe TFA(7432-24-8 free base) Gamma-Glutamylphenylalanine is a dipeptide composed of gamma-glutamate and phenylalanine, and is a proteolytic breakdown product of larger proteins. It is probably formed by transp
TP1266 γ-Glu-Phe TFA(7432-24-8 free base) Gamma-Glutamylphenylalanine is a dipeptide composed of gamma-glutamate and phenylalanine, and is a proteolytic breakdown product of larger proteins. It is probably formed by transp
TN2349 Taurodeoxycholate sodium salt Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. and it inhibits vari
TN2349 Taurodeoxycholate sodium salt Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. and it inhibits vari
T4858 4-Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the e
T4858 4-Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the e
T4834 Indole-3-acetamide 1H-Indole-3-acetamide, also known as auxin amide or 2-(3-indolyl)acetamide, belongs to the class of organic compounds known as 3-alkylindoles. Within the cell, 1H-indole-3-acetamid
T22235 Lipoic acid Lipoic acid is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
PDK0014 3-Methylxanthine 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.3-Methylxanthine inhi
T11366 Garcinol
T19295 Docosapentaenoic acid 22n-3 Docosapentaenoic acid 22n-3 is present in the cell membranes of all animals and is a component of phospholipids.
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