首页AutophagyDopamine Receptor
Dopamine Receptor
T0025 Haloperidol Haloperidol is a highly potent neuroleptic by relieving nervous through the depression of nerve function. In addition, haloperidol has shown about 50-fold efficacy than chlorpromaz
T0031 Ziprasidone hydrochloride monohydrate Ziprasidone(CP88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
T0031L Ziprasidone hydrochloride Ziprasidone (hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T0031L2 Ziprasidone Ziprasidone is an a typical antipsychotic used in the treatment of schizophrenia and bipolar disorder. Use of ziprasidone has not been consistently associated with serum enzyme
T0068 Fluphenazine hydrochloride Fluphenazine dihydrochloride is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly
T0074 Chlorprothixene Chlorprothixene is a typical antipsychotic drug of the thioxanthene class,which was the first of the series to be synthesized.
T0074L Chlorprothixene hydrochloride Chlorprothixene brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene is a typical antipsychoti
T0076 Paliperidone Paliperidone(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabo
T0082 Domperidone Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found
T0136 Citicoline Citicoline is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.
T0137 Mirtazapine Mirtazapine is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminot
T0162 Quetiapin Quetiapine is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is though
T0280 Spiperone Spiperone is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
T0287 Hexamethonium Bromide Hexamethonium Bromide, a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barri
T0302 Triflupromazine hydrochloride Triflupromazine hydrochloride, an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
T0322 Fipexide Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly fo
T0333 Aniracetam Aniracetam(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
T0338 Minaprine dihydrochloride Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T0351 Risperidal Risperidone is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
T0365 Thioridazine hydrochloride Thioridazine, an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
T0385 Prochlorperazine Maleate Prochlorperazine maleate is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPY
T0445 Promethazine Tafluprost(AFP-168) is an analogue of anti-glaucoma prostaglandin (PG) .
T0455 Clozapine Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacol
T0469 Octopamine hydrochloride Octopamine (OA) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates.
T0505 L-(-)-α-Methyldopa Methyldopa, an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic.
T0716 Molindone hydrochloride Molindone hydrochloride is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.
T0719 Tetrabenazine Tetrabenazine is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles
T0766 Promazine hydrochloride Promazine hydrochloride is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed be
T0776 Phenothiazine Phenothiazine is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the c
T0783 Mianserin hydrochloride Mianserin hydrochloride is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. It may ca
T0785 Dexchlorpheniramine Maleate Dexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmaco
T0811 Amisulpride Amisulpride (trade name Solian) is an antipsychotic drug sold by Sanofi-Aventis. It is not approved for use in the United States, but is approved for use in Europe and Australia
T0848 Levodopa Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross t
T0869 Atomoxetine hydrochloride Atomoxetine Hydrochloride is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cogni
T0990 Droperidol Droperidol is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist.
T1045 Trimipramine maleate Trimipramine maleate appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its acti
T1069 Metoclopramide hydrochloride Metoclopramide hydrochloride is a selective dopamine D2 receptor antagonist, used as an antiemetic.
T1090 Perphenazine Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
T1105 Penfluridol Penfluridol is a highly potent antipsychotic.
T1175 Bromopride Bromopride is a dopamine antagonist with prokinetic properties closely related to metoclopramide, and is widely used as an antiemetic. It is not available in the United States or t
T1180 Blonanserin Blonanserin is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side e
T1201 Sulpiride Sulpiride is a dopamine D2-receptor antagonist, used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.
T1211 Levosulpiride Levosulpiride is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class.
T1222 Trifluoperazine dihydrochloride Trifluoperazine Dihydrochloride is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.
T1233 Oxolinic acid Oxolinic acid is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
T1292 Tiapride hydrochloride Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative
T1322 Bendazol Bendazol is always used as the drug for hypertension and cerebral Angiospasm.
T1327 Nortriptyline hydrochloride Nortriptyline hydrochloride is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depres
T1336 Benztropine mesylate Benztropine mesylate is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopam
T1384 Chlorpromazine hydrochloride Chlorpromazine hydrochloride is the prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due t
T1406 Amantadine hydrochloride Amantadine hydrochloride is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T1412 Loxapine succinate salt Loxapine succinate, a D2DR and D4DR inhibitor, is utilized in schizophrenia.
T1471 Duloxetine hydrochloride Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLY
T1476 Pramipexole Pramipexole is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevation
T1517 Benserazide hydrochloride Benserazide Hydrochloride is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
T1539 Iloperidone Iloperidone is an atypical antipsychotic agent that is used for treatment of schizophrenia.
T1540 Doxepin hydrochloride Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is
T1567 Olanzapine Olanzapine is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T1644 Dopamine hydrochloride Dopamine is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1- an
T1735 Lurasidone hydrochloride Lurasidone hydrochloride is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, seroton
T1769 Pardoprunox Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the treatment of Early
T1871 GBR12935 GBR 12935 can induce the increase of the extracellular levels of dopamine to basal levels.
T2092 Amitifadine hydrochloride Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T2132 Buspirone hydrochloride Buspirone is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
T2190 Methiothepin mesylate Methiothepin mesylate is a potent and non-selective 5-HT2 receptor antagonist,used as an antipsychotic.
T2306 Brexpiprazole Brexpiprazole is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.
T2546 Pimozide Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the centr
T2564 Flupenthixol dihydrochloride Flupenthixol dihydrochloride is a dopamine receptor antagonist.
T2574 Alizapride hydrochloride Alizapride hydrochloride is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
T2592 Ropinirole hydrochloride Ropinirole a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole Hydrochloride is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparki
T2714 Rotundine Rotundine is extracted from Corydalis yanhusuo W. T. Wang.
T2874 Tetrahydroberberine THB Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
T3046 BMY 7378 dihydrochloride BMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
T3085 Piperacetazine Piperacetazine, an antipsychotic prodrug, is used forschizophrenia.
T3187 Fluoroclebopride Fluoroclebopride is a dopamine (DA) D2 receptor ligand.
T3278 Piribedil Piribedil is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T3337 Ddr1-In-1 DDR1-IN-1 is an effective and specific DDR1 receptor tyrosine kinase inhibitor (IC50: 105 nM), about 3-fold selectivity over DDR2.
T3369 Nuciferine Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade.
T3431 Pardoprunox hydrochloride Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist a
T3497 Ocaperidona Ocaperidona (Ocaperidone), a very high affinity dopamine D2 antagonist.
T3526 Dasotraline hydrochloride Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor  that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, a
T4081 MPTP-hydrochloride MPTP-hydrochloride is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism.
T4117 Zuclopenthixol Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
T6241 Quetiapine Fumarate Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T6647 Rotigotine Rotigotine is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine h
T6835 Fenoldopam mesylate Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
T6951 Pramipexole 2HCl Monohydrate Pramipexole Dihydrochloride is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors
T6988 SKF38393 HCl SKF38393 HCl is a selective dopamine D1/D5 receptor agonist.
T4274 Melitracen hydrochloride Melitracen Hydrochloride, an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.
T4369 SCH 23390 hydrochloride SCH 23390 hydrochloride is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
T2226 Pergolide mesylate salt PERGOLIDE MESYLATE is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEAR
T4616 5-Chloro-2-methoxyprocainamide Metoclopramide is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopram
T4577 Cariprazine Cariprazine is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A recepto
T4576 Perospirone Perospirone is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.
T5009 Trimethobenzamide hydrochloride Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
T5135 Fupentixol Dihydrochloride Flupentixol is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.
T5158 N-Desmethylclozapine N-Desmethylclozapine is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid recepto
T5380 Ansofaxine hydrochloride Ansofaxine (LY03005; LPM570065) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).
T5397 A-381393 A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).
T4262 BisfluoroModafinil CRL-40940 is a selective dopaminergic reuptake inhibitor
T5858 Sertindole Sertindole is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, re
T5842 Bromocriptine mesylate Bromocriptine is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)
T5954 Alpha-Methyldopa Sesquihydrate Alpha-Methyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system
T7180 Sultopride hydrochloride Sultopride Hydrochloride is a selective dopamine D2 and D3 receptor antagonist.
T7153 Vanoxerine dihydrochloride Vanoxerine dihydrochloride is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
T7308 Nomifensine Nomifensine is a norepinephrine-dopamine reuptake inhibitor that prevents dopamine reuptake into synaptosomes.
T7352 Pridopidine Pridopidine, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington di
T7569 Clebopride malate Clebopride malate is a dopamine antagonist drug Used to treat functional gastrointestinal disorders such as nausea or vomiting.
T7654 L-DOPA methyl ester (hydrochloride) L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.
T7553 (+)-PD 128907 hydrochloride (+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor .
T7632 Veralipride Veralipride is an antagonist of D2 receptor.
T7635 Raclopride Raclopride is a selective antagonist of dopamine D2/D3 receptor.
TQ0140 Sumanirole maleate Sumanirole maleate (U-95666E) is a highly selective full agonist of the D2 receptor (ED50: 46 nM).
TQ0175 Dexpramipexole Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
T7728 ACEPROMAZINE MALEATE ACEPROMAZINE MALEATE is a dopamine receptor antagonist
T7834 ABT-724 ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM)
T0255 Clomipramine hydrochloride Clomipramine hydrochloride is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastr
T4297 Flibanserin Flibanserin is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevat
T5387 LP-211 LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
T7943 Fluphenazine decanoate Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.
T8385 Metoclopramide hydrochloride hydrate Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic
T8382 Cariprazine HCl Cariprazine HCl is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)
TN1081 Hirsuteine Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death.
TN1424 Bacopaside X Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor.
T8389 Trifluoperazine Trifluoperazine is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
T12252 NRA-0160 NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)
T12288 Odapipam Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).
T12383 PD 168568 dihydrochloride PD 168568 dihydrochloride is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
T12405 Pentiapine Pentiapine is a novel inhibitor of dopamine release.
T12476 Pimozide D4 Pimozide D4 is a deuterium labeled Pimozide.
T12510 PNU-177864 hydrochloride PNU-177864 hydrochloride is a selective and orally active antagonist of dopamine D3 receptor,with antischizophrenic activity.
T10213 A-437203 A-437203 is a selective D3 receptor antagonist (Kis: 71, 1.6, and 6220 nM for D2, D3, and D4 receptors).
T10908 CY 208-243 CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.
T13652 Dicarbine Double carbene can be used for the study of schizophrenia and alcoholism. It can block dopamine receptors in various parts of the brain and prevent the reduction of conditioned def
T11078 Deschloroclozapine Deschloroclozapine is an effective selective chemical generation actuator. Decloclopine is a dual antagonist of dopamine and serotonin receptors. The Kis of dopamine D1, D2, D4 and
T14088 ABT-670 ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.
T8423 ML417 ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
T14767 BP 897
T12606 Quinpirole Hydrochloride Quinpirole Hydrochloride is a high-affinity dopamine D2/D3 receptor agonist.
T12676 (Rac)-Rotigotine hydrochloride (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.
T14782 Brilaroxazine Brilaroxazine (RP5603) is a partial agonist of dopamine (DA) D2, D3, and D4 receptors, 5-HT1A (Ki: 1.5 nM) and 5-HT2A (Ki: 2.5 nM), and has antagonist activity at 5-HT2B (Ki: 0.19
T14853 Cabergoline Cabergoline is an ergot derived-dopamine D2-like receptor agonist (Ki: 0.7, 1.5, and 1.2 for D2, D3, and 5-HT2B receptors).
T10837L Clocapramine Clocapramine is a D2 and 5-HT2A receptors antagonist.
T15100 Desmethyl cariprazine Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) recepto
T15117 Didesmethyl cariprazine Cariprazine is an antipsychotic drug candidate. It shows high affinity for the D3 and D2 receptors, and moderate affinity for the 5-HT1A receptor. Didesmethyl cariprazine is a meta
T13463L2 Dihydrexidine hydrochloride Dihydrexidine hydrochloride is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.
T13463L Dihydrexidine Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.
T15270 Fananserin Fananserin is an orally bioavailable and selective antagonist of the 5-HT2 receptor (Ki: 0.37 nM for the rat 5-HT2A receptor). It also is an antagonist of dopamine D4 receptor (Ki:
T15339 Foscarbidopa Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T12761 Ro 10-5824 dihydrochloride Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM).
T12861L SB-277011 dihydrochloride SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and
T12865 SCH-23390 maleate SCH-23390 maleate is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively).
T13898 SPD-473 citrate SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
T13570 Benzamide Derivative 1 Benzamide Derivative 1, extracted from patent EP0213775A1 (compound 18), may be useful in the treatment of gastrointestinal disorders.
T10612 Brexpiprazole S-oxide Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole. Brexpiprazole is a partial agonist of human 5-HT1A and dopamine receptors (Kis: 0.12 nM and 0.3 nM).
T10611 Brexpiprazole S-oxide D8 Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is a partial agonist
T10681 Cariprazine D6 Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
T10683 Carmoxirole hydrochloride Carmoxirole (EMD 45609) hydrochloride is a selective, peripherally acting agonist of dopamine D2 receptor with antihypertensive activities in vivo.
T11463 GR 103691 GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites. GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki va
T13164 Tipepidine hydrochloride Tipepidine hydrochloride ia a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK))(IC50 : 7.0 μM), with antidepressant-like effect.
T13240 U91356 U91356 is an agonist of dopamine receptor.
T13245 UCSF924 UCSF924 is a potent and specific agonist of dopamine D4 receptor (DRD4) partial (EC50 of 4.2 nM,Ki value of 3 nM)
T15686 L-741626 L-741626 is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).
T11799L L-745870 L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D2 (Ki of 960 nM) an
T15744 Levophacetoperane hydrochloride Levophacetoperane inhibits in vitro in a competitive manner. It also can norepinephrine uptake and dopamine uptake.
T13387 Zatebradine Zatebradine is a potent hyperpolarization-activated cyclic nucleotide-gated (HCN) channels inhibitor(IC50 of 1.96 µM).
T13468 (±)-Epibatidine (±)-Epibatidine is an agonist of nicotinic. (±)-Epibatidine is an agonist of neuronal nAChR.
T11728 JR-AB2-011 JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM). JR-AB2-011 has anti-glioblastoma multiforme (GBM) properties. JR-AB2-011 is a selective mTOR
T16472 Pericyazine Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe a
T16511 PF2562 PF2562 is a dopamine D1 ligand. It is used as a dopamine D1 agonist or partial agonist. PF2562 binds to human D1 receptor (Ki: 113 nM). PF2562 shows activity against human D1 cAMP
T11799 L-745870 hydrochloride L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0
T16759 Ritanserin Ritanserin is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM).
T16999 Tavapadon Tavapadon is an orally active and highly selective dopamine D1/D5 receptor partial agonist.
T17072 Thiethylperazine dimaleate Thiethylperazine maleate is a selective ABCC1 activator. Thiethylperazine maleate is also a phenothiazine derivate, and an orally active dopamine D2-receptor and histamine H1-recep
T8633 9-FLUORENOL 9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 µM, and a major metabolite of a compound developed as a wakefulness-promoting agent.
T1476L Pramipexole dihydrochloride Pramipexole dihydrochloride could be used to treat Parkinson disease.
T2S1397 L-Stepholidine L-Stepholidine, which has dual actions on dopamine D1 and D2 receptors, attenuates heroin self-administration and cue-induced reinstatement. It also elicits anti-dyskinesia effects
TN2856 Delta3,2-Hydroxylbakuchiol Delta3,2-Hydroxylbakuchiol, a monoamine transporter inhibitor involved in regulating dopaminergic and noradrenergic neurotransmission and may have represented potential pharmacothe
T8653 DOPEXAMINE Dopexamine is a dopaminergic agonist
T7070 Nomifensine (maleate) Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder.
T12352 Oxidopamine hydrochloride Oxidopamine hydrochloride is an neurotransmitter dopamine antagonist.
T8702 SKF-83566 SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM
  • 关注公众号
    - 超值特惠
    - 客户福利
    - 业界动态
    - 实用攻略
陶素的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)。