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DYRK
T2431 ID8 ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.
T2670 ML167 ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
T6257 AZ191 AZ191(IC50 of 17 nM) is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.
TQ0111 LDN-192960 LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).
T2811 Harmine hydrochloride Harmine hydrochloride is extracted from Peganum Harmala Genus.
T14364 AZ-Dyrk1B-33 AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor. With an IC50 of 7 nM[1].
T11132 DYRKs-IN-1  DYRKs-IN-1 has antitumor activity. DYRKs-IN-1 is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B an
T11133 DYRKs-IN-2 DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively.
T11447 GNF4877 GNF4877 leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells. GNF4877 is a potent DYRK1A and GSK3β inhibitor
T15579 INDY INDY is a potent and ATP-competitive inhibitor of Dyrk1A and Dyrk1B (IC50s: 0.24 μM and 0.23 μM, respectively). INDY sharply causes the self-renewal capacity of normal and tumor
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