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DNA Methyltransferase
T0018 Procainamide hydrochloride Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydr
T10840 CM-579 trihydrochloride CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cel
T10840L CM-579 CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.
T11469 GSK-3484862 GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.
T12790 Guadecitabine sodium Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .
T1339 5-Azacytidine Azacitidine, a pyrimidine nucleoside analogue of cytidine, blocks DNA methylation with antineoplastic activity.
T13954 UNC6852 UNC6852 is a selective degrader of PRC2 based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand (EED, IC50: 247 nM).
T1508 Decitabine Decitabine is a DNA methyltransferase inhibitor that incorporates into DNA resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication.
T15080 DC-05 DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).
T15081 DC_517 DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM).
T16287 Neurodazine Neurodazine is an imidazole-based small molecule, serves as a promoter of neurogenesisin pluripotent cells. Neurodazine selectively inhibits astrocyte differentiation of P19 cells.
T1904 SGI1027 SGI-1027 is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027 against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.
T19383 Isomaltotriose Isomaltotriose is a sugar from enzymic hydrolyzates of the dextran from Leuconostoc mesenteroides NRRL B-512.
T2038 RG108 RG108 is an DNA methyltransferase inhibitor(IC50=115 nM).
T2169 Zebularine Zebularine is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cy
T3089 Thioguanine Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
T3458 EED226 EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.
T3606 Gamma-Oryzanol Gamma-Oryzanol is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in
T5198 Bobcat339 hydrochloride Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
T7194 CM-272 CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
T7457 5-Methyl-2'-deoxycytidine 5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.
T7718 2'-DEOXY-5-FLUOROCYTIDINE 2'-DEOXY-5-FLUOROCYTIDINE is an  inhibitor of DNA methyltransferase (DNMT) .
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