| T0018 |
Procainamide hydrochloride |
Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydr |
| T10840 |
CM-579 trihydrochloride |
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cel |
| T10840L |
CM-579 |
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells. |
| T11469 |
GSK-3484862 |
GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer. |
| T12790 |
Guadecitabine sodium |
Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) . |
| T1339 |
5-Azacytidine |
Azacitidine, a pyrimidine nucleoside analogue of cytidine, blocks DNA methylation with antineoplastic activity. |
| T13954 |
UNC6852 |
UNC6852 is a selective degrader of PRC2 based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a VHL ligand (EED, IC50: 247 nM). |
| T1508 |
Decitabine |
Decitabine is a DNA methyltransferase inhibitor that incorporates into DNA resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. |
| T15080 |
DC-05 |
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively). |
| T15081 |
DC_517 |
DC_517 is an inhibitor of DNA methyltransferase 1 (DNMT1) ( IC50: 1.7 μM; Kd: 0.91 μM). |
| T16287 |
Neurodazine |
Neurodazine is an imidazole-based small molecule, serves as a promoter of neurogenesisin pluripotent cells. Neurodazine selectively inhibits astrocyte differentiation of P19 cells. |
| T1904 |
SGI1027 |
SGI-1027 is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027 against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively. |
| T19383 |
Isomaltotriose |
Isomaltotriose is a sugar from enzymic hydrolyzates of the dextran from Leuconostoc mesenteroides NRRL B-512. |
| T2038 |
RG108 |
RG108 is an DNA methyltransferase inhibitor(IC50=115 nM). |
| T2169 |
Zebularine |
Zebularine is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cy |
| T3089 |
Thioguanine |
Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia. |
| T3458 |
EED226 |
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM. |
| T3606 |
Gamma-Oryzanol |
Gamma-Oryzanol is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in |
| T5198 |
Bobcat339 hydrochloride |
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. |
| T7194 |
CM-272 |
CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor. |
| T7457 |
5-Methyl-2'-deoxycytidine |
5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo. |
| T7718 |
2'-DEOXY-5-FLUOROCYTIDINE |
2'-DEOXY-5-FLUOROCYTIDINE is an inhibitor of DNA methyltransferase (DNMT) . |
