| T0377 | Clofazimine | Clofazimine is a phenazine dye with anti-mycobacterial and anti-inflammatory activities. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against va |
| T0707 | Cyclophosphamide monohydrate | Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer. |
| T0923 | Busulfan | Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears t |
| T0942 | Quinacrine dihydrochloride | Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. |
| T0951 | Hydroxychloroquine sulfate | Hydroxychloroquine sulfate inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appear |
| T0975 | Chloroambucil | Chlorambucil is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption o |
| T11056 | DLK-IN-1 | DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, retains excellent CNS |
| T11440 | GNE-8505 | GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK). |
| T1241 | Altretamine | Altretamine is an alkylating agent with antineoplastic activity. |
| T1250 | Triethylenethiophosphoramide | Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity. |
| T12813L | Seco-Duocarmycin SA | Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin. |
| T1343L | Crystal Violet | Crystal violet is a triarylmethane dye that is a mixture of violet rosanilinis, with antibacterial, antifungal, and anthelmintic properties. |
| T1507 | Streptozocin | Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. |
| T1548 | 8-Methoxypsoralen | Methoxsalen is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of |
| T1601 | Lomustine | Lomustine is an alkylating agent of value against both hematologic malignancies and solid tumors. |
| T17159 | Treosulfan | Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types. |
| T17212 | VAL-083 | VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity. |
| T19300 | Duocarmycin Analog | Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin. |
| T2495 | Lomeguatrib | Lomeguatrib, a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) . |
| T3091 | Carmustine | Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent. |
| T3707 | GNE3511 | GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors. |
| T4024 | Norharmane | Norharmane is a natural β-carboline first isolated from plants of the Zygophyllaceae family. |
| T4187 | Gemcitabine monophosphate sodium salt hydrate | Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine. |
| T4350 | Palifosfamide | Palifosfamide lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most |
| T4368 | Miriplatin | Miriplatin (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC). |
| T5846 | Methylnitronitrosoguanidine | Methylnitronitrosoguanidine (MNNG) is an alkylating agent with toxic and mutagenic effects. |
| T6057 | URMC099 | URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM). |
| T6798 | Tretazicar | CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0 |
| T7221 | Satraplatin | Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malig |
| T7539 | O6-Benzylguanine | O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator. |
