||Dantrolene sodium salt
||Dantrolene is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neuromuscu
||Diltiazem Hydrochloride is a benzothiazepine calcium channel blocking agent with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.
||Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does
||Azelnidipine is a dihydropyridine used as calcium channel blocker.
||Felodipine is a longlasting 1, 4-dihydropyridine calcium channel repressor.
||Nisoldipine is a dihydropyridine calcium channel antagonist that acts as a potent arterial vasodilator and antihypertensive agent.
||Levetiracetam is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levetiracetam has been li
||Manidipine dihydrochloride is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).
||Ranolazine(RS-43285), an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and do not affect bloo
||Amlodipine Besylate is a long-lasting calcium channel blocker.
||Zonisamide, a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is
||Trimethadione is a dione-type anticonvulsant with antiepileptic activity.
||Fendiline is a non-selective blocker of calcium channel.
||Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
||Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
||Ethosuximide is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
||Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in the prophylaxis of
||Cinnarizine is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DI
||Isradipine is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of c
||Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not
||Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.
||Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
||Nifedipine is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscl
||Trimebutine maleate is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors served as a spasmolyti
||Nicardipine Hydrochloride is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine
||An anticonvulsant that is the active metabolite of TRIMETHADIONE.
||Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
||Nilvadipine, a calcium channel blocker (CCB), is utilized for treatment of hypertension.
||Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and para
||Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex t
||Otilonium Bromide, an antimuscarinic, is utilized as a spasmolytic agent.
||Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, a
||Strontium ranelate, a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The dru
||NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor.
||Efonidipine(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.
||Lercanidipine is a calcium channel blocker of the dihydropyridine class.
||1-Ethyl-2-benzimidazolinone is a calium channel agonist.
||Tetrandrine is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade
||Phenylalanine is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.
||(±)-trans-ACPD is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. (±)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); active at the gro
||SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger.
||NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).
||ABT-639 is a potent and selective T-type calcium channel blocker.
||Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
||Manidipine, a calcium channel blocker, which is dihydropyridine type. It is utilized
||Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia i
||Bay K 8644
||Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
||Lercanidipine is a calcium channel blocker of the dihydropyridine class.
||(S)-Amlodipine Besylate (103129-82-4(free base))
||Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipine belongs to the dih
||1. Heteroclitin D can inhibit L-type calcium channels. 2. Heteroclitin D might be a valuable antitumor promoter or chemopreventor.
||1. Pulegone has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive
||Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
||Fantofarone is a highly potent Calcium Channel antagonist.
||Addition of the Rhamnose-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-si
||Aranidipine (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects.
||Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels.
||MK-8998 as potent inhibitors of T-type calcium channels.
||Barnidipine is a dihydropyridine calcium channel blocker that has an IC50 value of 0.35 nM in potassium-induced tonic contraction of pig coronary artery
||Mirogabalin is a calcium channel blocker with analgesic effects.
||NP118809 is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
||DHBP dibromide is calcium release and a muscle relaxant inhibitor.
||Barnidipine is a calcium channel blocker.
||Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort.
||CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).
||(S)-(-)-Bay K 8644
||(S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. It activates Ba2+ currents (IBa) (EC50: 32 nM).
||(R)-(+)-Bay K 8644
||(R)-(+)-Bay K 8644 is a calcium channel inhibitor. It inhibits Ba2+ currents (IBa) (IC50: 975 nM).
||Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).
||Thapsigargin is a microsomal Ca2+-ATPase inhibitor and Endoplasmic Reticulum stress-inducing agent.
||Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
||Gabapentin is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical Activity.
||Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.
||Efonidipine hydrochloride monoethanolate
||Efonidipine hydrochloride monoethanolate is a Ca(2+)-channel Blocker, Enhances the Production of Dehydroepiandrosterone Sulfate in NCI-H295R Human Adrenocortical Carcinoma Cells
||6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.
||Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of a
||(+)-R-Coclaurine and (+)-S-reticuline show negative inotropic effects, coclaurine derivatives and of paeoniflorin derivatives have neuromuscular blocking actions.
||Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ transients in the cell body and neur
||Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scavenging activity and i
||Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the
||Periplocymarin, a cardiac glycoside, has potential anti-cancer activity.
||Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects, it also shows stro
||Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems; they show strong effects on cell growth inhibition and apoptosis i
||Geissoschizine methyl ether
||Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is a po
||Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
||Procyanidin A1 has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.
||7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
||Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small ce
||Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
||Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic activation of heter
||Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of [Ca2+]i that is at
||Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistres
||Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatati
||Ethyl cinnamate has antifungal, and vasorelaxant effects, it can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with
||Sodium taurochenodeoxycholate is one of the main bioactive substances of animals' bile acid. Sodium taurochenodeoxycholate induces apoptosis and shows obvious anti-inflammatory an
||Mibefradil dihydrochloride is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respe
||MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).
||N-type calcium channel blocker-1
||N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.
||NecroX-5 is a derivative of the NecroX and with anti-inflammatory and anti-cancer activity.
||Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice.
||Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .
||ORM-10962 is a potent, highly selective inhibitor of sodium-calcium exchanger (NCX) (for the reverse and forward mode inhibition with IC50 values of 67 and 55 nM , respectively).
||Palonidipine is an antagonist of calcium, is potential for the therapy of angina-pectoris and hypertension.
||PD0176078 is a newly blocker of N-type Calcium channel.
||Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosoli
||Dehydronitrosonisoldipine is a calcium channel antagonist.
||Dopropidil is a new anti-angina pectoris calcium regulator, which has intracellular calcium antagonist activity and anti-ischemic effects in various predicted animal models.
||DS16570511 is a cellular osmotic inhibitor of mitochondrial calcium monoab, which blocks MCU or MICU1-dependent Ca2+ influx.
||(R)-Lercanidipine D3 hydrochloride
||(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.
||(R)-Lercanidipine hydrochloride is the R-enantiomer of Lercanidipine. (R)-lercanidipine hydrochloride is a blocker of calcium channel.
||Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and
||Etripamil is an antagonist of short-acting L-type calcium-channel for the treatment of Paroxysmal Supraventricular Tachycardia.
||Fluspirilene is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM). It is a long-acting injectable depot antipsychotic drug used for schizophrenia.
||Gallopamil hydrochloride is a methoxy derivative of Verapamil and is a phenylalkylamine calcium antagonist. It is a potent antiarrhythmic and vasodilator agent. Gallopamil hydrochl
||(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.
||SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM
||Semotiadil recemate fumarate
||Semotiadil recemate fumarate is the recemate of Semotiadil fumarate. Semotiadil fumarate is a novel antagonist of vasoselective Ca2+ channel.
||SQ-31765 is a blocker of benzazepine calcium channel.
||Teludipine hydrochloride is a blocker of lipophilic calcium channel.
||Tiapamil hydrochloride is a blocker of calcium channel.
||Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyv
||CALP3 TFA（261969-05-5 free base)
||CALP3 TFA is a potent Ca2+ channel blocker that activates EF-hand motifs of Ca2+-binding proteins. It can functionally mimic increased [Ca2+]i by modulating the activity of Calmodu
||CCR4 antagonist 2
||CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Mi
||Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM), selectively kills melanoma cells with S100B over those
||TTA-Q6 is a selective antagonist of T-type Ca2+ channel, used in the neurological disease.
||UK51656 is an antagonist of calcium (IC50: 4 nM).
||AE0047 Hydrochloride is a blocker of calcium, and used in the research of the hypertensive disease.
||Iganidipine is an antagonist of Ca2+ .
||Levamlodipine besylate is a powerful dihydropyridine calcium channel blocker. It has possessing vasodilation properties and used in the treatment of hypertension and angina.
||Lidoflazine is a high-affinity blocker of the HERG K+ channel and is an antianginal calcium channel blocker. It carries an obvious risk of QT interval prolongation and ventricular
||IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity.IPR-803 is a potent inhibitor of the uPAR•uPA protein-protein interaction (PPI).
||NSC 663284 is a cell-permeable and irreversible Cdc25 dual specificity phosphatase inhibitor (IC50 for Cdc25B2: 0.21 μM). NSC 663284 inhibits NSD2 (IC50 of 170 nM) through direct
||Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflamma
||β-Amino Acid Imagabalin Hydrochloride
||β-Amino Acid Imagabalin Hydrochloride is the voltage-dependent calcium channel ligand for the α2δ subunit.
||Pranidipine is an effective, long-acting 1,4-dihydropyridine calcium channel blocker. It also has antihypertensive activity.
||GSK-7975A is a potent and orally available inhibitor of CRAC channel.
||McN5691 is a voltage sensitive calcium channel blocker.
||Sipatrigine is a glutamate release inhibitor and voltage-dependent sodium channel.
||trans-Ned 19 is a NAADP antagonist and TPC blocker and inhibits the calcium signal in human umbilical vein endothelial cells and the rat aorta relaxation in response to low histami
||Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function
||Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes suc
||Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA me
||Euxanthone has vasorelaxation effect, may be through multiple pathways involved PKC-mediated signal pathway and calcium-independent pathway, it induces its vasodilator effect throu
||Reticuline is a key compound in the biosynthetic pathway for isoquinoline alkaloids in plants, which include morphine, codeine and berberine. Reticuline possesses potent central ne
||Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activit
||Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to
||1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by in
||15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid s
||2,3-Dihydroxy-4-methoxyacetophenone is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.
||ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane involve the activation
||4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
||ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than 10 microg /mL for mo
||9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably
||Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activi
||Calceolarioside A shows potent activity against visceral leishmaniasis. It can induce a dose-related aggregant effect on rabbit platelets, which may be partly related to a calcium-
||Cinnamyl caffeate has cardiovascular protective effects, it can increase H9c2 cellular antioxidant potential, decrease intracellular calcium ion ([Ca2+]i) level, and prevent cell a
||Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoinositides breakdown induced by collagen and thrombin, it inhibits the aggregation and AT
||Didrovaltrate shows cytotoxic against human cancer cell lines. Didrovaltrate blocks I(Ca-L) in a concentration-dependent manner and probably inhibits I(Ca-L) in its inactive state,
||Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
||Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil de
||Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupanine improves gluco
||Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
||(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium
||Strophanthidin can induce calcium overload in vivo.
||Taxezopidines K and taxezopidine L can markedly inhibit Ca2+-induced depolymerization of microtubules.
||Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles.
||Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows pote
||SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
||Norverapamil hydrochloride ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) fu
||Cinepazide maleate, a maleate salt form of cinepazide, is a vasodilator.
||Dantrolene sodium hemiheptahydrate
||Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine recepto
||Ginsenoside Rd may have properties that inhibit or prevent the growth of tumors.
||Catharanthine Tartrate(2468-21-5(free base))
||Catharanthine Tartrate is a natural product isolated from Madagascar periwinkle, Catharanthine Tartrate inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pr
||Nicardipine hydrochloride, a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
||MDK-4025 is an inhibitor of the high voltage-activated (HVA) Ca2+ current in pyramidal neurons.
||RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
||ZSET-1446 is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.
||1. Rhynchophylline can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can i
||Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the therapy of cardiovascular diseases.
||2-Aminoethoxydiphenyl borate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at higher concentrations).
||HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
||HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
||Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA)nanomol