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CRM1
T1844 KPT-330 KPT-330 is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells.
T6074 KPT-276 KPT-276 is an orally bioavailable selective inhibitor of nuclear export (SINE) that irreversibly bind to CRM1 and block the function of CRM1.
T6123 Verdinexor Verdinexor (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
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