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CETP
T13079 TAP311 TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).
T13423 (1R,2R)-2-PCCA(hydrochloride) (1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and is a potent agonist of GPR88 receptor(EC50 of 3 nM and 603 nM in cell-free assay and in cell assay).
T15004 CP-532623 CP-532623, a close structural analog of Torcetrapib, is a CETP inhibitor with highly lipophilic properties. It elevates high-density lipoprotein cholesterol.
T15570 Implitapide Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T16266 NAMI-A NAMI-A is a ruthenium-based drug characterized by the selective activity against tumor metastases. NAMI-A inhibits adhesion and migration.
T1928 Anacetrapib Anacetrapib (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester
T2499 Torcetrapib Torcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in p
T2545 Lomitapide Mesylate Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.
T4S2157 Campesterol Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti
T6048 Dalcetrapib Dalcetrapib, a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
T6262 Evacetrapib Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
T6267 Lomitapide Lomitapide is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing di
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