T1368 |
Methyl protocatechuate |
Methyl protocatechuate is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect. |
T1882 |
Methylisoindigotin |
Meisoindigo is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML). |
T2733 |
Sarsasapogenin |
Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtr |
T2799 |
(20S)-Protopanaxadiol |
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin. |
T3299 |
AT-406 HCl |
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with K |
T3488 |
Tectorigenin |
Tectorigenin is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation and in vivo Bone Re |
T3771 |
Methyl protodioscin |
Methyl protodioscin potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced a |
T3796 |
Betulinaldehyde |
Betulinaldehyde has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activ |
T3902 |
Atractylenolide III |
Atractylenolide III may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the |
T3908 |
10-Gingerol |
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracel |
T3916 |
Ginsenoside F2 |
Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitocho |
T4189 |
4-Oxofenretinide |
4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis. |
T4004 |
Concanavalin A |
Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts. |
T4241 |
Rubiadin |
Rubiadin possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner. |
T5132 |
9-dihydro-13-acetylbaccatin III |
9-Dihydro-13-acetylbaccatin III is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR. |
T3008 |
2-Methoxynaphthoquinone |
MNQ induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these signaling |
T3759 |
3,4-Dimethoxycinnamic acid |
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effect |
T5514 |
Epibrassinolide |
Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mamm |
T2S1396 |
3-O-Acetyloleanolic acid |
3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G1 apoptotic cell pop |
T5780 |
HYPOCRELLIN B |
HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits |
T5793 |
Britannin |
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells. |
T5753 |
Flavokawain C |
Flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava.FKC has the potential to be developed into chemotherapeutic drug for the treatment of colon ade |
T7337 |
Kinetin riboside |
Kinetin riboside can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM) |
TQ0016 |
NKP-1339 |
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. |
TQ0112 |
Tubulysin A |
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, and anti-angi |
T2S2382 |
3'-Hydroxypterostilbene |
3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116, |
T5S1000 |
Sophoraflavanone G |
Sophoraflavanone G (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. |
T8282 |
(-)-Perillyl Alcohol |
(S)-(−)-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. It also has anti |
T8297 |
Gomisin N |
Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy and inhibits prolifer |
TN2103 |
PROCYANIDIN C1 |
Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis. |