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Apoptosis inducer
T1368 Methyl protocatechuate Methyl protocatechuate is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect.
T1882 Methylisoindigotin Meisoindigo is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
T2733 Sarsasapogenin Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtr
T2799 (20S)-Protopanaxadiol (20S)-Protopanaxadiol (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.
T3299 AT-406 HCl AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with K
T3488 Tectorigenin Tectorigenin is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation and in vivo Bone Re
T3771 Methyl protodioscin Methyl protodioscin potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced a
T3796 Betulinaldehyde Betulinaldehyde has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activ
T3902 Atractylenolide III Atractylenolide III may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the
T3908 10-Gingerol 10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracel
T3916 Ginsenoside F2 Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitocho
T4189 4-Oxofenretinide 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.
T4004 Concanavalin A Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts.
T4241 Rubiadin Rubiadin possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner.
T5132 9-dihydro-13-acetylbaccatin III 9-Dihydro-13-acetylbaccatin III is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR.
T3008 2-Methoxynaphthoquinone MNQ induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these signaling
T3759 3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effect
T5514 Epibrassinolide Epibrassinolide (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with a similar structure to mamm
T2S1396 3-​O-​Acetyloleanolic acid 3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G1 apoptotic cell pop
T5780 HYPOCRELLIN B HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage, induces apoptosis in ovarian cancer cells, and inhibits
T5793 Britannin Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.
T5753 Flavokawain C Flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava.FKC has the potential to be developed into chemotherapeutic drug for the treatment of colon ade
T7337 Kinetin riboside Kinetin riboside can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)
TQ0016 NKP-1339 NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
TQ0112 Tubulysin A Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, and anti-angi
T2S2382 3'-Hydroxypterostilbene 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 µM for COLO 205, HCT-116,
T5S1000 Sophoraflavanone G Sophoraflavanone G (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.
T8282 (-)-Perillyl Alcohol (S)-(−)-Perillyl alcohol, a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. It also has anti
T8297 Gomisin N Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy and inhibits prolifer
TN2103 PROCYANIDIN C1 Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
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