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Antifection
Fr14115 Terpineol α-Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-
Fr14298 2'-Hydroxy-4'-methylacetophenone 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.
T0120 Voriconazole Voriconazole is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.
T0146 Vagistat Tioconazole is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, alt
T0344 Miconazole Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion.
T0444 Econazole Econazole is an imidazole derivative that is commonly used as a topical antifungal agent.
T0444L Econazole nitrate Econazole nitrate (Spectazole) is an imidazole class antifungal medicine.
T0506 Clotrimazole Clotrimazole, an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.
T0681 Rifampicin Rifampicin is an antibacterial drug of the class of rifamycin.
T0688 Ganciclovir Ganciclovir is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated c
T0863 Dendrid Idoxuridine is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
T0868 Cefepime Dihydrochloride Monohydrate Cefepime Dihydrochloride Monohydrate is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium
T0884 Behenic alcohol Docosanol is a saturated 22-carbon aliphatic alcohol with antiviral activity. Docosanol has a distinct mechanism of action and inhibits fusion between the plasma membrane and th
T1000 Chlorhexidine Chlorhexidine is a biguanide compound used as an antiseptic agent with topical antibacterial activity. Chlorhexidine is positively charged and reacts with the negatively charged mi
T1000L Chlorhexidine Acetate Chlorhexidine acetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
T1079 Metronidazole Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T1147 Chlorhexidine hydrochloride Chlorhexidine hydrochloride is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
T1190 Cefmenoxime hydrochloride Cefmenoxime hydrochloride is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative micr
T1290 Oxiconazole nitrate Oxiconazole Nitrate is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fu
T1388 Fluconazole Triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.
T1643 Penciclovir Penciclovir is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted b
T2213 Terconazole Terconazole is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergost
T2S1115 Albaspidin AA Albaspidin AA displays strong antibacterial activity against the vegetative form of P. larvae (MIC ranging from 0.168-220 uM). It may have in vitro nematocidal activity against L4
T2S1635 3-Isomangostin 3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scaveng
T2S1727 Lycorenine Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and
T2S2363 Corydine Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant
T3831 Licoricone Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.
T3897 Isoschaftoside Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoscha
T3S0006 Methyl ferulate Methyl ferulate is a possible inhibitor of the mitogen activated phosphor kinase pathway, it could be a potential anti-inflammatory agent isolated for the first time in medicinal p
T3S0631 Fuziline Fuziline shows significant insecticidal activity against Nilaparvata legen and Aphis medicagini. Fuziline shows activity against pentobarbital sodiuminduced cardiomyocytes damage b
T3S1088 Isoforsythiaside Isoforsythiaside has antioxidant, and antibacterial activities.
T3S1534 Secoxyloganin Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin pos
T3S1692 Octahydrocurcumin Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF
T4131 Arjunic acid Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9
T4201 Avibactam sodium Avibactam is a reversible β-lactamase inhibitor (IC50: 8/80/38 nM, for TEM-1/P99/KPC-2 β-lactamases).
T4202 Delamanid Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall.
T4237 Rubiadin 1-methyl ether Rubiadin-1-methyl ether probed as Type I photosensitizers. Rubiadin 1-methyl ether decreases the number of parasites (schizonts) in a dose-dependent manner, and 100% of inhibition
T4484 1,7-Dihydroxy-2,3-methylenedioxyxanthone 1,7-Dihydroxy-2,3-methylenedioxyxanthone has antiulcerogenic, anti-oxidation, and antihyperalgesic activities, it can inhibit the carrageenan-induced hyperalgesia.
T4672 Brevilin A Brevilin A is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STAT
T4960 VASICINE Vasicine is oxytocic and abortifacient agents.Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. Vasicine can reg
T5188 GC376 sodium GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.
T5527 Anigorufone Anigorufone is a phytoalexin, it shows striking antinematode activity. Anigorufone has shown inhibitory activity on the growth of the germinative tube of Fusarium oxysporum f. sp.
T5544 2-Furoic acid 2-Furoic acid, an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss includi
T5602 Benzylpenicillin potassium Benzylpenicillin potassium is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.
T5691 paulownin Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.
T5722 Nevadensin Nevadensin is an important herb-based constituent inhibiting estragole bioactivation. Nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F3
T5746 Dictamnine Dictamnine shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cerv
T5776 pimpinellin Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
T5778 5,7-DIMETHOXYFLAVONE 5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
T6207 SC144 SC144 is an orally active small-molecule gp130 inhibitor.
T7059 alpha-Dihydroartemisinin Dihydroartemisinin is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs, is recommended as the first-line anti-malarial drug with lo
T7733 Cefotaxime Cefotaxime is an inhibitor of penicillin binding protein.
T7869 Nicoform Nicoform is an antimicrobial agent.
T7999 7-Hydroxyflavanone 7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.
T8019 Sorbic acid Sorbic acid is a natural product that inhibits various bacteria, including sporeformers,
T8121 Octacosanoic acid Octacosanoic acid has antiplatelet and antithrombotic effects.
T8133 SulfadiMethoxine sodium Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infections
T8247 (+)-Aromadendrene (+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
T9113 Myristicin Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and
TC0017 Haplopine Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells.
TCS1772 Dehydroabietic acid 1. Dehydroabietic acid (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insuli
TJS1382 Taraxerone Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol a
TJS1748 Methyl protogracillin Methyl protoneogracillin shows cytotoxic activitiy against the cancer cell line of K562 in vitro as antineoplastic agents. It can cause morphological abnormality of Pyricularia ory
TJS2216 Asperglaucide Asperglaucide shows some nematocidal property against M. incognita.
TL0013 Heraclenin Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it h
TL0015 Pyromeconic acid Pyromeconic acid and derivatives thereof are potent inhibitors of endonuclease
TL0016 Sulforaphene Sulforaphene may be a potential anti- triple negative breast cancer natural compound and its /\''antiproliferation effects may be mediated by tumor suppressor Egr1; it has chemothe
TL0018 Lobelin Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing.
TMA0017 Sideroxylin Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of th
TMA0164 15-Hydroxydehydroabietic acid 15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities.
TMA0394 Methyl tanshinonate Methyl tanshinonate has antioxidant activity, it can treat psoriasis.
TMA0395 Danshenxinkun D Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro.
TMA0507 Tomatidine Tomatidine shows antibiotic, and anti-inflammatory activities, it significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. Tomatidine inhibits the inv
TMA0955 Thunberginol C Thunberginol C exhibits antimicrobial activity against oral bacteria. It shows antiallergic activity in the in vitro bioassay using the Schults-Dale reaction in sensitized guinea p
TMA1743 Ergosterol peroxide Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inh
TMA2418 1-Methoxyphaseollidin 1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may
TN1012 Febrifugine Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity .
TN1041 Quercetin-7-O-beta-D-glucopyranoside Quercetin-7-O-beta-D-glucopyranoside has antibacterial activity, it shows promising activity against Staphylococcus aureus.
TN1063 Calycanthine D-calycanthine has antifungal activity, it shows significant inhibitory activities against five plant pathogenic fungi Exserohilum turcicum, Bipolaris maydis, Alternaria solani, Sc
TN1084 Desmethylbellidifolin Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method; it also exhibits at the dose of 200 ug/disk a significa
TN1099 Dihydroevocarpine Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a moderate modulator
TN1108 Kaempferol 3-O-beta-sophoroside Kaempferol 3-O-beta-sophoroside has antibacterial and antiviral activities.
TN1113 Vincetoxicoside B Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
TN1114 Carabrone Some of carabrone derivatives exhibit antifungal activities in vitro or in vivo, the compounds with a pyridinyl residue can either efficiently inhibit spore germination or efficien
TN1117 Veraguensin Veraguensin shows activity against trypomastigote T. cruzi., it shows high antileishmanial activity.
TN1120 Osthenol Osthenol shows antitumor-promoting activity, it also has antifungal and antibacterial activities.
TN1121 Evocarpine Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
TN1130 Yadanziolide A Yadanziolide A shows strong antiviral activity.
TN1133 Isocolumbin Isocolumbin has anti-inflammatory, and antimicrobial activities.
TN1144 Enmein Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml
TN1145 Isofebrifugine Isofebrifugine shows antimalarial activity.
TN1162 1,2-Benzenedicarboxylic acid 1,2-Benzenedicarboxylic acid is one kind of allelochemical shows stronger allelopathic effect on itself than on wheat and pigeonpea.
TN1167 1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside 1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside shows certain antibacterial activity.
TN1203 2,3,8-Tri-O-methylellagic acid 2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia
TN1213 2-(Hydroxymethyl)anthraquinone 2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc.
TN1215 2'-Methoxykurarinone 2'-Methoxykurarinone has strong alpha-glucosidase inhibitory activities, with IC(50) values of 155 microM. 2'-Methoxykurarinone is a noncompetitive inhibitor of protein tyrosine ph
TN1242 3,8-Di-O-methylellagic acid 3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of s
TN1262 3-O-Feruloylquinic acid 3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
TN1301 6,8-Diprenylgenistein 6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.
TN1302 6,8-Diprenylorobol 6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals.
TN1329 7-Ethoxyrosmanol 7-Ethoxyrosmanol has cytotoxic and antimicrobial activities.
TN1342 8-Epidiosbulbin E acetate 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.
TN1343 8-Geranyloxypsoralen 8-Geranyloxypsoralen inhibits α²-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-G
TN1344 8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone 8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone may have antifungal activity against phytopathogenic and human pathogenic fungi.
TN1349 9-Hydroxycalabaxanthone 9-Hydroxycalabaxanthone exhibits cytotoxicity against the HT-29 cell line with ED50 values of 9.1 microM. The combination of 9-hydroxycalabaxanthone with α±-mangostin shows the s
TN1375 alpha-Lapachone alpha-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.
TN1402 Arjungenin Arjungenin shows α²-glucuronidase inhibitory activity, it shows antiviral, and anti-inflammatory activities.
TN1409 Asimilobine (-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α±-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Strep
TN1417 Azadirachtin Azadirachtin has antifungal activity, it used as insecticides.
TN1427 Baicalin methyl ester Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
TN1432 Bacopasaponin C Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
TN1436 Methyl 4-Hydroxyphenylacetate Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV).
TN1442 Betulinic acid methyl ester Betulinic acid methyl ester showed antiplasmodial activity against chloroquine-resistant Plasmodium falciparum parasites in vitro.It also inhibited B16 2F2 cell proliferation by in
TN1444 bis[6-(5,6-dihydrochelerythrinyl)]amine BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
TN1451 Brevifolincarboxylic acid Brevifolincarboxylic acid shows moderate antibacterial activity against Salmonella enteritidis , Salmonella typhimurium , and Salmonella abony, it (IC50 = 18.0 μM) also shows good
TN1453 Bruceantinol Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.
TN1463 Calycanthoside Isofraxidin-7-O-glucoside(Calycanthoside ) has the anti-inflammatory effect, it has inhibitory activity on NO production.It also shows antibacterial activity.
TN1466 Canthin-6-one Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; it also has antiinflammatory activity by i
TN1481 Cerebroside B Cerebroside B1b has antiulcerogenic activity.
TN1484 Cheilanthifoline Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marro
TN1513 Clitorin Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.
TN1521 Colutehydroquinone Colutehydroquinone and colutequinone are antifungal isoflavonoids from Colutea arborescens.
TN1522 Combretol Combretol has leishmanicidal activity, it showed moderate activity (growth inhibition 87.3 and 73.0 %, respectively, at 50 μM) against a multidrug-resistant L. tropica line. Combr
TN1526 Corydalmine Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of al
TN1527 Corynoxidine Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. It inhibits acetylcholinesterase activity in a dose-depend
TN1530 Cowaxanthone B Cowaxanthone B shows weak antibacterial activity.
TN1531 Cratoxylone Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC50 value belows 3 μM.
TN1538 Curzerenone Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52).
TN1556 Decarine Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-i
TN1560 Dehydroeffusol Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties, it may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in
TN1561 Dehydroglaucine Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus nige
TN1568 Deoxyartemisinin Deoxyartemisinin can inhibit microbial growth and reproduction,and is therefore likely to influence biochemical reactions in soils.
TN1569 Deoxylapachol Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius
TN1594 DL-Syringaresinol (+)-Syringaresinol shows inhibitory activity of Helicobacter pylori motility with the IC50 value is 50 microg/ml.
TN1632 Euparin Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect dur
TN1637 Eurycomalactone Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 μM.
TN1668 Ganoderic acid Y Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.
TN1673 Garcinone C Garcinone C is a potent inhibitor of AChE.
TN1689 Glabranin Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to s
TN1694 Gliotoxin Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway.
TN1695 Globulol Globulol shows antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 microg/ mLand 737.2 microg/ mL, respectively.
TN1699 Glyasperin D Glyasperin D possesses weak anti-Helicobacter pylori activity.
TN1703 Glycyrin Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
TN1714 Grosvenorin Grosvenorine exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastr
TN1722 Hamamelitannin Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary g
TN1733 Hesperetin 7-O-glucoside Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA r
TN1772 Isoastilbin Isoastilbin has anti-acne and tyrosinase inhibition properties.
TN1778 Isoformononetin Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymph
TN1790 Isopteropodine Isopteropodine has antimicrobial activity, it shows strong apoptotic effects on acute leukaemic lymphoblasts, it also shows an ability to stimulate the immune system.
TN1792 Isorhamnetin 3-glucoside-7-rhamnoside An anti-oxidative composition containing isorhamnetin-3-glucoside-7-rhamnoside (IGR)isolated from Hippophae rhamnoides L. is provided to ensure antioxidative, antibacterial, and an
TN1814 Juncusol Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 cells. Juncusol has an
TN1821 Kaempferol 3-O-arabinoside Kaempferol-3-O-α±-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxidants in biologica
TN1838 Kulactone Kulactone has cytotoxic effects, with IC50 values of 5.6-21.2ug/mL, it inhibited (ED(50) 2.5-6.2 microg/mL) the P388 cancer cell line.
TN1839 Kumatakenin Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.
TN1842 Kushenol I Kushenol I is a GABAA receptor modulator, it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).Kushenol I is shown to be active against the plant
TN1853 Lariciresinol Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for th
TN1860 Licoflavone B Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.
TN1861 Licoflavone C Licoflavone C has cytotoxic, and antioxidative effects, it has protective effect toward the chromosome damage induced by DAU or MMC in cultured human peripheral lymphocytes. Licofl
TN1862 Licoflavonol Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the s
TN1864 Licoisoflavone B Licoisoflavone B is an inhibitor of germ tube growth in the arbuscular mycorrhizal (AM) fungus Gigaspora margarita, it can strongly inhibit germ tube growth at 0.63 ug/disc.
TN1877 Lonicerin Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
TN1897 Luteone Luteone possesses antifungal activity sufficient to support its proposed role as pre-infectional resistance factors.
TN1905 Magnolioside Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial a
TN1906 Magnoloside A Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml.
TN1913 Marmin Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the
TN1919 Medioresinol Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α²-se
TN1928 Methyl rosmarinate Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).
TN1930 Methylenetanshinquinone Methylenetanshinquinone shows antiplasmodial and antitrypanosomal activity, it is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.
TN1931 Methyllinderone Methyllinderone is a human chymase inhibitor, it has antioxidant property, it also shows moderate to weak antifungal activities against various pathogenic fungi.
TN1938 Mogroside VI Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial properties, no-calorie le
TN1955 Mucrolidin Mucrolidin shows weak antibacterial activity.
TN1977 Neochamaejasmine B Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.
TN1979 Neocnidilide Neocnidilide has insecticidal activity, it exhibits LC50 values of 9.90 micromol/mL of diet concentration against larvae of D. melanogaster. Neocnidilide has antifungal activity. I
TN1985 Neoprzewaquinone A Neoprzewaquinone A has algicidal effect on M. aeruginosa , with EC50 of 4.68 mg /L, the potential inhibition mechanisms are neo-przewaquinone A caused M. aeruginosa cells morpholog
TN1991 Norchelerythrine Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activit
TN1993 Norsanguinarine Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) val
TN2011 Ombuoside Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.
TN2027 Oxysanguinarine Oxysanguinarine possesses antiplatelet aggregation activity, it has potential inhibitory properties against dengue virus.
TN2032 Pachypodol Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida a
TN2047 Pendulone Pendulone could be a valuable chemopreventive agent, it shows strong inhibition on the effect of the cell cycle induced by TPA and shows potent anti-tumor-promoting activity for an
TN2058 Persicogenin Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/
TN2063 Physalin B Physalin B shows antimalarial, anti-Trypanosoma cruzi, anti-bacterial, anti- leukemia activities, it has the potential to be developed as an effective chemotherapeutic lead compoun
TN2074 Pilocarpine Pilocarpine has been used to treat glaucoma, ocular hypertension and xerostomia.
TN2078 Pinocembrin chalcone Pinocembrin chalcone has tyrosinase inhibitory activity.It also shows antimutagenic effect, which is mainly due to the inhibition of the first step of enzymatic activation of heter
TN2085 Piperlonguminine Piperlonguminine is an efficient depigmenting agent with a novel mechanism of action.
TN2101 Primin Primin has antimycobacterial, and strong antineoplastic actions.
TN2111 Prunin Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells
TN2120 Quassin Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion.
TN2160 Roemerine Roemerine is a potential active xanthine oxidase(XOD) inhibitor, XOD is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to t
TN2172 Saikosaponin I Saikosaponin I shows strong inhibition activity against influenza virus WSN33.
TN2190 Scoulerine Scoulerine shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively. It
TN2219 Sophoraisoflavone A Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 u
TN2246 Swertiajaponin Swertiajaponin possesses antimicrobial activity.
TN2249 (+)-Syringaresinol (+)-Syringaresinol shows antioxidant potential, it exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2.
TN2252 Syrosingopine Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor.
TN2256 Taccalonolide B Taccalonolide B displays microtubule stabilizing activity.Several taccalonolides have in vitro antitrypanosomal activity against Trypanosoma brucei brucei and EC50 values for the i
TN2271 Thalrugosaminine Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. Thalrugosaminine possesses hypotens
TN2277 Torachrysone 8-O-glucoside Torachryson-8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.
TN2278 Torachrysone Torachrysone shows promising antioxidant activity. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strains of methicillin-re
TN2279 Totarol Totarol has anti-bacteria effect by restraining bacterial growth by perturbing the cell division and proliferation, including several pathogenic Gram-positive bacteria, mycobacteri
TN2293 Valechlorine Valeranone shows antileishmanial and cytotoxic activity.
TN2311 Wulignan A1 Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.
TN2315 Xanthopurpurin Xanthopurpurin shows antiviral activity, it can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly stron
TN2321 Yadanzioside L Yadanzioside L shows strong antiviral activity.
TN2392 9,17-Octadecadiene-12,14-diyne-1,11,16-triol 9,17-Octadecadiene-12,14-diyne-1,11,16-triol shows antibacterial activity against Bacillus subtilis and Pseudomonas fluorescens, antifungal activity against Cladosporium cucumerinu
TN2417 Furomollugin Furomollugin has antiviral activity, it can strongly suppress the secretion of hepatitis B surface antigen (HBsAg), with IC50 = 2.0 micrograms/mL, in human hepatoma Hep3B cells.
TN2475 1(10)-Aristolen-2-one 1(10)-Aristolen-2-one has antifungal activity.
TN2485 1,2-Dihydrotanshinquinone 1,2 Dihydrotanshinquinone is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.
TN2489 1,3,7-Trihydroxy-2-prenylxanthone 1,3,7-Trihydroxy-2-prenylxanthone shows weak antibacterial activity against the bacterium.
TN2495 1,4,7-Eudesmanetriol 1α,4β,7β-Eudesmanetriol and 1β,4β,7β-Eudesmanetriol can inhibit growth of Pseudomonas stutzeri with a MIC value of 117 uM, they also show remarkable activities against acetyl
TN2515 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in
TN2524 1-Acetyl-beta-carboline Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.
TN2548 1-Methoxyberberine 1-Methoxyberberine chloride is a potential antifungal agent.
TN2567 10-Hydroxycanthin-6-one 10-Hydroxycanthin-6-one has potential to be an antimicrobial agent. 10-Hydroxycanthin-6-one has in vitro antimalarial activity; it also has cytotoxic activity, it could be a plant
TN2579 11,13-Dihydroivalin Standard reference
TN2623 14-Deoxy-17-hydroxyandrographolide Standard reference
TN2625 14-Deoxycoleon U 14-Deoxycoleon U has anti-termitic activity, it is highly active against both wood-decay fungi. 14-Deoxycoleon U shows antibacterial activity against the Gram-positive bacteria Sta
TN2626 14-Norpseurotin A 14-Norpseurotin A shows good antileishmanial and moderate anticancer activities. It also displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis,
TN2650 16-Oxocleroda-3,13E-dien-15-oic acid 16-Oxocleroda-3,13E-dien-15-oic acid shows antiplasmodial activity.
TN2685 2,3,24-Trihydroxy-12-ursen-28-oic acid 2α,3α,24-Trihydroxyurs-12-en-28-oic acid, a triterpenoid phytoalexin, shows antifungal activity against the fungus mentioned. It also shows in vitro cytotoxic activity against tu
TN2686 2,3,24-Trihydroxyolean-12-en-28-oic acid 2α,3α,24-Trihydroxyolean-12-en-28-oic acid, a triterpenoid phytoalexin, isolated from peel of unripe fruits of nectarine (Prunus persica cv Fantasia), shows antifungal activity a
TN2697 2,3-Dihydrohinokiflavone 2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMPs) gene expression. It (IC50 =1.6uM) shows strong activity against Leishmania.
TN2711 2'',4''-Di-O-(E-p-coumaroyl)afzelin Antimicrobial agent.
TN2723 Jatrophane 3 (2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R*,3R*, 4S*,5R*,7S*,8S*
TN2727 Jatrophane 2 2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene (Jatrophane 2 ) exhibits significant antifeedant activity against a generalist plant-feeding insect, the co
TN2728 Jatrophane 4 (2R*,3R*,4S*,5R*,7S*,8S*,9S*,l3S*,14S*,15R*)-2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene(Jatrophane 4 ) and (2R*,3R*, 4S*,5R*,7S*,8S*
TN2730 2,5-Dihydroxybenzaldehyde 2,5-Dihydroxybenzaldehyde has antioxidant activity.
TN2736 2',6'-Dihydroxy-4'-methoxyacetophenone 2',6'-Dihydroxy-4'-methoxyacetophenone is a phytoalexin after fungal inoculation with Botrytis cinerea or UV light irradiation, it has spore germination inhibition on Botrytis cine
TN2738 2,6-Dimethoxy-1-acetonylquinol 2,6-Dimethoxy-1-acetonylquinol shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum. It is devoid of significant cytotoxicity to the human oral epi
TN2747 2-Acetoxy-3-deacetoxycaesaldekarin E 2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.
TN2755 2-Desoxy-4-epi-pulchellin 2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging
TN2760 2-Hydroxy-1,8-cineole 1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescens) .
TN2767 2'-Hydroxygenistein 2'-Hydroxygenistein has antifungal activity, dimerization of it causes a remarkable increase of antifungal activity. It shows significant concentration-dependent inhibitory effects
TN2772 2-Methoxyanofinic acid 2-Methoxyanofinic acid is active against the plant pathogenic fungus Cladosporium cucumerinum.
TN2774 2-Methoxyphenalen-1-one 2-Methoxy-1H-phenalen-1-one (2-Methoxyphenalen-1-one) displays significantly enhanced activity against Mycosphaerella fijiensis in comparison with other phenylphenalenones.
TN2798 20-Deoxocarnosol 20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to hi
TN2809 22-Dehydroclerosterol 22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori.
TN2820 24-Methylenecycloartan-3-ol 24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli.
TN2849 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid 2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities
TN2864 3',4',5',3,5,6,7-Heptamethoxyflavone
TN2866 3,4,5-Trimethoxycinnamyl alcohol 3,4,5-Trimethoxycinnamyl alcohol shows significant antimicrobial and cytotoxic activities.
TN2867 3,4,5-Trimethoxyphenyl-(6-O-galloyl)-O-beta-D-glucopyranoside 3,4,5-Trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside shows in vitro antiplasmodial activity.
TN2876 3,4-Dihydroxy-2-methoxyxanthone 3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly is
TN2898 3,5-Dihydroxy-4',7-dimethoxyflavone 3,5-Dihydroxy-4',7-dimethoxyflavone shows antioxidant activity, it also shows significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concen
TN2931 3-Epikatonic acid Epikatonic acid shows less active against T. (S.) cruzi trypanosome.
TN2977 3-O-trans-p-Coumaroyltormentic acid 3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL6
TN3013 4,5-Dimethoxycanthin-6-one 4,5-Dimethoxycanthin-6-one has antibacterial actiyity, it exhibits inhibition against Staphylococcus aureus and its drug-resistant strains. 4,5-Dimethoxycanthin-6-one has a strong
TN3027 4-Epialyxialactone 4-Epialyxialactone exhibits significant antitumor and antibacterial activity.
TN3039 4-Hydroxyalternariol 9-methyl ether 4-Hydroxyalternariol 9-methyl ether displays promising antioxidant effects. It also shows antibacterial activity against several tested bacterial pathogens with minimum inhibitory
TN3063 4-O-Methylsappanol 4-O-Methylsappanol shows activity against this fungus against Beauveria bassiana.
TN3080 5,6,7-Trimethoxycoumarin 5,6,7-Trimethoxycoumarin shows moderate inhibitory activity against Micrococcus luteus, it also displays an intermediate cytotoxic effects against brine shrimp larvae. 5,6,7-Trimet
TN3110 5-Geranoxy-7-methoxycoumarin 5-Geranoxy-7-methoxycoumarin shows antifungal activity.
TN3112 5-Heneicosylresorcinol 5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cells. 5-Heneicosylreso
TN3116 5-Hydroxy-1-methoxyxanthone 5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of mon
TN3124 5-Hydroxysophoranone 5-Hydroxysophoranone exhibits high antiplasmodial activity against Plasmodium falciparum (IC50=2.5 microg/mL).
TN3145 6,7-Dihydroneridienone A 6,7-Dihydroneridienone A exhibits notable leishmanicidal activity.
TN3151 6-Acetonyl-N-methyl-dihydrodecarine 6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae.
TN3160 6-Deoxyisojacareubin 6-Deoxyisojacareubin shows moderate inhibitory activity against the QGY-7703 cell line, with the IC50 value of 9.65 uM; it also possesses potency in the inhibition of protein kinas
TN3161 6-Deoxyjacareubin 6-Deoxyjacareubin possesses significant antioxidant activities, it also exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.6-Deoxyjacar
TN3177 6-Methyl-5,6-dihydropyran-2-one 6-Methyl-5,6-dihydropyran-2-on is bactericidal,and antiprotozoal agents.
TN3214 7,4'-Dihydroxy-3'-prenylflavan 7,4'-Dihydroxy-3'-prenylflavan has antibacterial activity.
TN3220 7',8'-Dihydroobolactone 7',8'-Dihydroobolactone can inhibit Trypanosoma brucei brucei with an IC(50) of 2.8 microM.
TN3221 7-Angeloylretronecine 7-Angeloylretronecine may have antibacterial effects.
TN3260 8(14),15-Isopimaradien-3-ol ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than 10 microg /mL for mo
TN3276 8-Epixanthatin 8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O. cumana at nano- to
TN3318 9-Hydroxy-alpha-lapachone 9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4
TN3355 Agatharesinol acetonide Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM).
TN3363 Agrimonolide 6-O-glucoside Agrimonolide-6-O-glucopyranoside has antimicrobial activity.
TN3397 Alpinumisoflavone Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is endowed with estroge
TN3400 Altechromone A Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, an
TN3401 Altenuene Altenuene is a mycotoxin, it frequently occurs in food and feed items infested by fungi of the genus Alternaria. Altenuene demonstrates moderate activity against Staphylococcus aur
TN3404 Altholactone Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of various types of ca
TN3409 Anagyrine Anagyrine, is the responsible teratogen from teratogenic lupins, can produce congenital deformities in calves typical of crooked calf disease; it also can induce red cell aplasia,
TN3422 Anisofolin A Anisofolin A has promising antimalarial activity (IC50 4.39 ± 0.25 uM). It has promising antimycobacterium activity [IC50 4.50 ± 0.75 uM (3.31 ug/mL)] against M. tuberculosis H37
TN3427 Aphadilactone B Aphadilactone B shows significant antimalarial activity with the IC50 value of 1350 ± 150 nM.
TN3438 Arborinine Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0.7 ug/ml. Arborinin
TN3450 Artanin Artanin displays promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64 ug/ml, but very weak against Gram-negative pathogen and yeast
TN3452 Arteannuin M Arteannuin has antimalarial activity. It can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation.
TN3453 Arteannuin N Arteannuin has antimalarial activity. It can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation.
TN3456 Artoheterophyllin B Artoheterophyllin B has antiplasmodial activity.
TN3460 Asebogenin Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, respectively); it show
TN3465 Atalantoflavone Atalantoflavone shows urease inhibitory potential. It displays weak cytotoxic activity against the human Caucasian prostate adenocarcinoma cell line PC-3.
TN3490 Barbinervic acid Barbinervic acid shows anti-bacteria activity (IC50 = 0.098 g x LU(-1), IC50 = 0.27 g x L(-1)) against SA and ESBLs-SA respectively.
TN3495 Benzyl ferulate Benzyl ferulate has antimicrobial activity. It also shows good anti-proliferative against three gastro-intestinal cancer cell lines(HCT-116 colon carcinoma, KYSE-30 oesophageal squ
TN3500 beta-Amyrone beta-Amyrone has antifungal activity, it also shows a moderate activity against Chikungunya virus replication (EC50 =86 uM). beta-Amyrone exhibits anti-α-glucosidase inhibitory ac
TN3507 beta-Yohimbine Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it
TN3528 Bonducellpin D Bonducellpin D may show inhibitory activities on the Para3 virus. It also exhibits moderate activity against four tested human cancer cell lines, HepG-2, K562, HeLa, and Du145.
TN3540 Broussonin C Broussonin C and broussin are antifungal compounds. Broussonin C exerts simple reversible slow-binding inhibition against diphenolase.
TN3547 Bullatantriol Bullatantriol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. It may have weak antibacterial activities.
TN3549 Burchellin Burchellin has larvicidal activity, it can interfer with the development cycle of the mosquito, where its strongest toxic effect is 100% mortality in larvae (L3) at concentrations
TN3557 Cabraleadiol Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol inhibits photosyste
TN3560 Cabralealactone Cabralealactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line, it is moderately active against a
TN3563 Caesalmin B Caesalmin B shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.
TN3564 Caesalmin E Caesalmin E shows anti-Para3 virus activity.
TN3568 Calceolarioside A Calceolarioside A shows potent activity against visceral leishmaniasis. It can induce a dose-related aggregant effect on rabbit platelets, which may be partly related to a calcium-
TN3573 Camaric acid Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it also shows moderate
TN3580 Cannabispirol Cannabispirol has a weak antibacterial effect which is more definite on plasmid carrying bacteria than plasmidless ones, and inhibits intercellular plasmid transfer and transformin
TN3583 Canophyllal Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs.
TN3584 Canthin-6-one N-oxide Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities.
TN3603 Carpinontriol B Carpinontriol B has antimicrobial activity, it at 40 ug/disk caused the formation of zones of inhibition. It also has anti-inflammatory activity, it shows considerable inhibition o
TN3616 Cedrelone Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fasciatus. Cedrelone a
TN3626 Cerbinal Cerbinal is a potent antifungal compound.
TN3627 Chalepensin Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction thr
TN3637 Chloramultilide B Chloramultilide B exhibits moderate in vitro antifungal activity.
TN3644 Chlorophorin Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg/ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM; i
TN3650 Chrysothol Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast canc
TN3670 Citromycin Citromycin, an antibiotic, has weakly cytotoxic.
TN3674 Clauszoline M Clauszoline M shows a significant anti-tuberculosis activity.
TN3680 Cleroindicin F Cleroindicin F shows cytotoxic activity against some human cancer cells. Cleroindicin F and apigenin in the ethyl acetate extract provide scientific support to the traditional use
TN3691 Communic acid Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic ingredients, as th
TN3699 Corchoionoside C Corchoionoside C has antioxidant activity, shows strong scavenging activities on DPPH radical, it also shows weak antifungal activity. Corchoionosides A, B, and C inhibit the hista
TN3707 Coronarin B Coronarin B has cytotoxic activity, it also has modest antiplasmodial activity.
TN3708 Coronarin D Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4
TN3710 Coronarin E Coronarin E exhibits weak antimicrobial activity.
TN3713 Corymbosin Corymbosin shows significant antiviral activity.
TN3714 Corypalmine Corypalmine (IC50=128.0±10.5 uM) can inhibit prolyl oligopeptidase. (-)-Corypalmine shows inhibition activity against spore germination of some fungi.
TN3719 Cristacarpin Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxyg
TN3721 Cryptofolione Z-Cryptofolione and Cryptomoscatone D2 as highly efficacious inhibitors of the G(2) checkpoint, G(2) checkpoint inhibitors can force cells arrested in G(2) phase by DNA damage to e
TN3723 Cryptomeridiol Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low activity against A. n
TN3729 Cuniloside B Cuniloside B shows anti-leishmanial activity.
TN3735 Cycloart-23-ene-3,25-diol Cycloart-23-ene-3,25-diol has anti-inflammatory activity, it has protective activity against streptozotocin induced toxicity. Cycloart-23-ene-3,25-diol treatment can decrease liver
TN3747 Cynatratoside A Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis.
TN3778 De-4'-O-methylyangambin De-4'-O-methylyangambin exhibits antibacterial effects. It also has analgesia activity.
TN3779 De-O-methyllasiodiplodin De-O-methyllasiodiplodin exhibits radical scavenging, moderate antibacterial, and potential anti-inflammatory effects, it shows moderate suppression effects on induced NO productio
TN3790 Dehydroabietinol Dehydroabietinol inhibits growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM)
TN3797 Dehydrobruceine A Dehydrobruceine A shows strong antitrypanosomal activities with IC(50) values in the range of 2.9-17.8nM.
TN3799 Dehydrocrebanine Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng
TN3834 Derrone Derrone may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. It is also a novel Aurora kinase inhibitor, it can significantly in
TN3852 Dihydrolicoisoflavone Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals.
TN3861 Dihydropinosylvin Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum
TN3896 Drimenol Drimenol shows antifungal activity, it is able to affect Botrytis cinerea growth with the EC50 value of 80 ppm. Drimendiol also shows quorum sensing inhibition activity.
TN3907 (E)-3-Hydroxy-5-methoxystilbene (E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Myco
TN3913 Echimidine Echimidine, a major hepatotoxic dehydropyrrolizidine alkaloid produced by E. plantagineum, in the honey (780 ng/g) and in the subsequent mead samples (236-540 ng/mL). Echimidine-N-
TN3920 Effusanin A Effusanin A has antibacterial activity. It exhibits DNA-damaging activity in assay which employed DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains. Effusa
TN3921 Effusanin B Effusanin B shows antibacterial activity. It exhibits DNA-damaging activity in assay which employes DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains.
TN3922 Effusanin E Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-
TN3943 ent-17-Hydroxykauran-3-one ent-17-Hydroxy-16α-kauran-3-one shows weak antimicrobial activity when tested against Staphylococcusaureus.
TN3978 Epitaraxerol Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. su
TN3987 Eriodictyol chalcone Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.
TN3990 Erysenegalensein E Standard reference
TN3995 Erythrabyssin II Erythrabyssin II actives against several strains of Staphylococcus and Streptococcus with an MIC range of 0.78-1.56 microg/ml. It inhibits bacterial neuraminidase in a dose-depende
TN4010 Erythrocentaurin Erythrocentaurin has antibacterial activity; it also exhibits a concentration-dependent α-amylase inhibition (IC(50) 1.67 ± 0.28 mg/mL).
TN4014 Esculentoside B Phytolaccoside B(Esculentoside B) is an antifungal monodesmoside triterpenoid glycoside, it has potent inhibitory activity against agrobacterial plant transformation.
TN4023 Eucalyptin Eucalyptin has antioxidant and antimicrobial properties, it exhibits potent antimicrobial activities against seven micro-organisms with minimum inhibitory concentrations (MIC) rang
TN4028 Euchrestaflavanone B Euchrestaflavanone B shows antibacterial activity against Gram positive bacteria, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. Euchrestaflavanone B may function by
TN4040 Eupatoriochromene Eupatoriochromene retard seed germination , reduced radicle and hypocotyl growth of weed and crop plant seedlings and increased adventitious root formation of mung bean cuttings. E
TN4045 Evofolin C Evofolin C and its acetate show strong antifungal and antibacterial activity. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide
TN4053 FD-838 FD-838 shows good antileishmanial and moderate anticancer activities, it can moderately inhibit the growth of cultured P388 and HL-60 cell lines. FD-838 has anti-fungal activity, i
TN4071 Formoxanthone A Formoxanthone A may have antibacterial and cytotoxic activities.
TN4084 Fumitremorgin B Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progre
TN4097 Gancaonin G Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans.
TN4098 Gancaonin I Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.
TN4108 Ganoderic acid Z The binding affinities of ganoderic acid DM and ganoderic acid Z (ΔGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal
TN4113 Garcinone E Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, wi
TN4148 Glyasperin C Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of
TN4159 Goniodiol (+)-Goniodiol and 7-epi-(+)-Goniodiol show high antibacterial activity (MIC, 3.1 mM) against Yersinia intermedia.
TN4167 Grifolic acid Grifolic acid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol/L. Grifolic acid has antibacterial activity
TN4183 Hardwickiic acid Hardwickiic acid modulates hippocampal [(3)H]NA overflow evoked by a mild depolarizing stimulus by acting at presynaptic opioid receptor subtypes. Hardwickiic acid shows antimicrob
TN4202 (-)-Heraclenol (-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol has moderate antibact
TN4212 Hirsutanonol Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. Hirsutan
TN4213 Hirsutenone Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation.Hirsutenon
TN4218 Homaloside D Homaloside D has antiplasmodial activity.
TN4223 Homopterocarpin Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopteroca
TN4227 Horminone Horminone has antimicrobial activity, it can inhibit the protein synthesis in several types of bacteria; it can inhibit the in vitro growth of Trypanosoma cruzi, 30 microM drug con
TN4229 Humulene epoxide II Humulene epoxide II has antimalarial activity.
TN4234 Hydrangenol Hydrangenol is a strong contact sensitizer found in hydrangea (Hydrangea sp.; Hydrangeaceae), it can significantly inhibit the passive cutaneous anaphylaxis (PCA) reaction, it has
TN4261 Isoaltenuene Isoaltenuene shows antibiotic activity against Gram-positive bacteria; it also shows a minor phytotoxic activity on tomato leaves at level of 20 ug/spot . Isoaltenuene exhibits cyt
TN4264 Isoapetalic acid Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gra
TN4266 Isobonducellin Isobonducellin exhibits potent cytotoxic activity in Jurkat and HepG2 cells, while moderate growth inhibition against Colon205 cells.
TN4267 Isoboonein Isoboonein exhibits significant antitumor and antibacterial activity.
TN4271 Isochamaejasmine Isochamaejasmine has inhibition of NF-kappaB activation, which could reverse the anti-apoptotic effect; it induces apoptosis in leukemia cells by inhibiting the activity of Bcl-2 f
TN4274 Isocostic acid Isocostic acid may have antibacterial activity.
TN4275 Isocudraniaxanthone A Isocudraniaxanthone A may have antimalarial activity.
TN4276 Isocudraniaxanthone B Isocudraniaxanthone B may have antimalarial activity.
TN4283 Isodiospyrin Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. Isodiospyrin has antibacterial activity, the minimum inhibitory con
TN4288 Isoferulic acid Isoferulic acid is an effective natural antioxidant in both lipid and aqueous media, it may be a new promising anti-glycation agent for the prevention of diabetic complications via
TN4300 Isojacareubin Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin
TN4308 Isolupalbigenin Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM), it also shows in vitro inhibitory activity toward human glyoxalase I. Isol
TN4314 Isonardoperoxide Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M).
TN4319 Isopimaric acid Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64
TN4336 Isothymusin Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity against the radical scaven
TN4373 Kaempferol tetraacetate Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1.
TN4375 Kamebanin Kamebanin, a natural diterpenoid, has antibacterial activity. It also shows efficient cytotoxic activity against HeLa and HL-60 cells.
TN4387 Khellactone Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial activities, they show
TN4388 Kielcorin Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils
TN4399 Kushenol C Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows a
TN4402 Labd-13-ene-8,15-diol 13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 mi
TN4403 Lactupicrin Lactupicrin has antimicrobial and anti-cancer effects, it also protect the plant from insect feeding.
TN4420 Latifolin Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays poten
TN4433 Licoarylcoumarin Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-
TN4443 Lipiferolide Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against
TN4449 Longistylin C Longistylin A and longistylin C show some cytotoxic effects, with IC(50) values of 0.7-14.7 microM against the range of cancer cell lines. Longistylin A and longistylin C, and betu
TN4462 Lupeol caffeate Lupeol caffeate has anti-malarial activity.
TN4465 Luvangetin Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection against pylorus-ligated a
TN4470 Lyoniside Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, su
TN4471 Lysicamine Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL
TN4473 Macrocarpal A Macrocarpal A is the key component that stimulates the synthesis of ceramide in the stratum corneum. Macrocarpal A has cytotoxic, and antibacterial activities.
TN4475 Macrocarpal C Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifung
TN4476 Macrocarpal D Macrocarpal D is a HIV-RTase inhibitor. It has antibacterial activity.
TN4478 Macrocarpal H Macrocarpal H has anti-glucosyltransferase, and anti-bacterial activities.
TN4479 Macrocarpal I Macrocarpal I has anti-glucosyltransferase, and anti-bacterial activities.
TN4480 Macrocarpal J Macrocarpal J has anti-bacterial activity, it also has anti-glucosyltransferase activity.
TN4490 Manassantin B Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replicati
TN4518 Meridinol Meridinol has wide antimicrobial activity, includes against gram-positive and gram-negative bacteria and fungi.
TN4530 Methyl 3-hydroxy-4,5-dimethoxybenzoate Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2. It shows obvious antimicrobial activities, the minimum inhibitory conce
TN4531 Methyl 3-O-feruloylquinate Methyl 3-O-feruloylquinate inhibits the activity of bacteria and viruses and to regulate immunity.
TN4535 Methyl 6-acetoxyangolensate Methyl-6-acetoxy angolensate may have antimalarial activity.
TN4536 Methyl 6-hydroxyangolensate Methyl 6-hydroxyangolensate shows antifungal and antibacterial activities.
TN4551 Methyl orsellinate Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa cr
TN4578 Monomethyl kolavate Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM.
TN4579 Monomethylsulochrin Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderately inhibitory effec
TN4581 Moracin D Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization of Moracin may open
TN4585 Moronic acid Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified t
TN4588 Mulberrofuran H Mulberrofuran H exhibits potent antifungal activity against phytopathogenic fungi Colletotrichum orbiculare, Phytophthora capsici, Corynespora cassiicola and Fusarium oxysporum.
TN4594 Murraol Murraol shows the significant proliferative activities on osteoblast-like UMR106 cells lines at the concentration of 1 × 10-10 mol/L. It and auraptenol show 63 ug/mL MIC value aga
TN4596 Musellactone Musellactone shows different effects against five bacteria strains.
TN4623 Nagilactone C Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere wi
TN4634 Neocyclomorusin Neocyclomorusin displays minimal inhibitory concentration (MIC) value of 4 ug/mL against Klebsiella pneumoniae ATCC11296, Enterobacter cloacae BM47.
TN4648 Nepetoidin B Nepetoidin B has anti-fungal, anti-bacterial, and antiinflammatory effects, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated by MKP-5/NF-κB p
TN4649 Neridienone B Neridienone B has significant effects on calcein accumulation. Neridienone exhibits significant leishmanicidal activity against amastigotes of L. mexicana.
TN4650 Nervogenic acid Nervogenic acid has antioxidative, pro-coagulant, and antibacterial activities, it exhibits higher activity than that of t-butyl-4- hydroxyanisole (BHA) using the ferric thiocyanat
TN4652 Niazimicin Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin has potent antitumor promoting activity in the two-stage carc
TN4653 Niazinin Niazinin shows antileishmanial activity against promastigotes of Leishmania donavani, with an IC50 value of 5.25 microM.
TN4656 Nigracin
TN4660 Niranthin Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interac
TN4666 Norcaesalpinin E Norcaesalpinin E shows antimalarial activity against the malaria parasite Plasmodium falciparum FCR-3/A2 clone in vitro, with an IC50 value of 0.090 microM.
TN4670 Norlichexanthone Norlichexanthone has the potential to treat and/or prevent lifestyle-related diseases, including metabolic syndrome, type 2 diabetes, atherosclerosis and cardiovascular diseases.No
TN4673 (+)-Nortrachelogenin (+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 +/- 1.8 microM. (+)-
TN4675 Nortrachelogenin Nortrachelogenin is a novel agent for prostate cancer therapy with ability to inhibit Akt membrane localization and activity as well as the activation of growth factor receptors, t
TN4683 Nyasol Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhib
TN4692 Octadecyl p-coumarate A mixture of (E)-octadecyl p-coumarate and (Z)-octadecyl p-coumarate has antifungal activity , it shows the dose dependent inhibition of the spore germination of Alternaria alterna
TN4696 Odorinol Odorine and odorinol inhibit both the initiation and promotion stages of two-stage skin carcinogenesis. (+)-Odorinol exhibits strong antiviral activity against Ranikhet disease vir
TN4717 Oplopanone Oplopanone exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strain.
TN4725 Oxychelerythrine Oxychelerythrine shows high modulatory activity enhancing the susceptibility of the S. aureus ATCC 6538 to all the tested antibiotics from two to four-fold. It also shows antifeedi
TN4731 Pachyaximine A Pachyaximine A possesses significant antibacterial activity against Escherichia coli, Staphylococcus aureus, Corynebacterium diphtheriae and Corynebacterium pyrogenes. (-)-Pachyaxi
TN4733 Pancixanthone A Pancixanthone A may have antimalarial activity, it also shows a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and again
TN4742 Patulitrin Patulitrin has antioxidant, anti-inflammatory, and larvicidal activities, oral and topical administration of patuletin and patulitrin inhibited acute inflammation in mice.
TN4748 Penduletin Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Penduletin has strong acti
TN4760 Phaseollidin hydrate Phaseollidin hydrate shows less antifungal activity than the original phytoalexin phaseollidin.
TN4776 Physalin D Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. Physalin
TN4778 Physalin H Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) valu
TN4797 Piperolactam C Piperolactam C possesses anti-platelet aggregation activity in vitro. It can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides.
TN4804 Platycoside A Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG
TN4808 Platyphyllenone Platyphyllenone has shown promising anti-filarial activity both in vitro and in vivo studies. It can inhibit the biosynthesis of violacein in C. violaceum CV026.
TN4822 Prehelminthosporol Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient upt
TN4834 Protoplumericin A Protoplumericin A displays distinct activity against some pathogenic bacteria and fungi.
TN4838 Pseurotin A Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora
TN4851 Pterodondiol Pterodondiol has moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans.
TN4852 Pterodontic acid Pterodontic acid and pterodondiol showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis.
TN4871 Pyrolin Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
TN4906 Rengynic acid Rengynic acid has potent antiviral effect on RSV for the first time in vitro.
TN4927 Rupesin E Rupesin E shows significant antibacterial activities against Escherichia coli.
TN4932 Sageone Sageone represents a promising anticancer agent against gastric cancer that warrants further study, it synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells.Sa
TN4933 Sahandol Sahandol shows antiprotozoal activity against P. falciparum and T. brucei rhodesiense.
TN4953 Sativan Sativan possesses a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi, it exhibits antituberculosis activity against Mycobacterium tuberculosis H3
TN4968 Scopoline Scopoline, tropinol, ecgonine, and granatoline derivatives are therapeutic agents of the pyrrole and pyridine group. Scopoline has fungitoxic effects, it is inhibitory to Sclerotin
TN4990 Seneganolide Seneganolide has insect antifeeding activity. Seneganolide A has antifungal activity.
TN5012 Shizukaol C 1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxicities against C8166 c
TN5014 Shoreic acid Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also s
TN5020 (+/-)-Sigmoidin A Sigmoidin A has moderate antioxidant, antimicrobial and anti-inflammatory activity.
TN5021 Sikokianin C Sikokianin C shows antimalarial activity against the chloroquine-resistant strain of Plasmodium falciparum, with the IC (50) value of 0.56 microg/mL.
TN5030 Sitoindoside I Sitoindoside I has anti-ulcerogenic activity.
TN5034 Beta-Solamarine Beta-Solamarine has antibacterial activity.
TN5039 Sorokinianin Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug/ml concentration.
TN5061 Stephanine l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine sh
TN5067 Stigmastane-3,5,6-triol Stigmastane-3,5,6-triol and derivatives could be used for preparing antiviral medicine.
TN5071 Stilbostemin N Stilbostemins N may exhibit moderate antibacterial activities.
TN5079 Sulochrin Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotoxicity up to 50 uM.
TN5082 Swietemahalactone Swietemahalactone exhibits antibacterial activity.
TN5091 Tagitinin A Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the growth of STS and we
TN5092 Tagitinin F Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes.
TN5117 Taxiphyllin Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against Staphylococcus aur
TN5119 Taxoquinone Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foodborne pathogens. It
TN5134 Tetrahydroxysqualene Tetrahdroxysqualene shows antimycobacterial activity with an MIC of 10.0 microg/mL, while showing only modest cytotoxicity.
TN5139 Thalifoline Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
TN5152 Topazolin Topazolin has weak fungitoxic activity, it displays significant activity against Salmonella typhimurium ATCC 13311 with MIC values ranging from 2 to 8 ug/mL, it also shows in vitro
TN5173 Trichorabdal A Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori.
TN5190 Tryprostatin A Tryprostatin A is an inhibitor of breast cancer resistance protein. Tryprostatin A and tryprostatin B are indole alkaloid-based fungal products that inhibit mammalian cell cycle at
TN5201 Uncarinic acid E Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resulting in cytochrome
TN5223 Vasicinolone Vasicinolone has anti-inflammatory, and antimicrobial activities.
TN5227 (+/-)-Vestitol Vestitol has antioxidation, anti-inflammatory and antimicrobial activities, it can strongly act in a low dose and concentration and have a promising potential to be applied in the
TN5228 Vestitol Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose
TN5229 Vibralactone B Vibralactone B shows antibacterial activity, it can inhibit significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 ug/mL, respectively.
TN5243 Vitexilactone Vitexilactone is a HIV-1 reverse transcriptase inhibitor in virtual screening against Indonesian Herbal Database using AutoDock4 performed on HIV-1 reverse transcriptase. It has tr
TN5245 Vitexolide D Vitexolide D shows moderate antibacterial activity against a panel of 46 Gram-positive strains. It also shows cytotoxic activities against the HCT-116 cancer cell line and human fe
TN5254 Wighteone Wighteone is an antifungal isoflavone.Wighteone has in vitro cytocidal activity against KB cells, it has a potent anti-proliferative effect on human leukemia HL-60 cancer cell line
TN5264 Xanthoxyletin Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory effect on iNOS prot
TN5267 Yadanzioside I Yadanzioside I shows strong antiviral activity.
TN5278 Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of
TN5279 Zeorin Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows pote
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