首页AutophagyAdrenergic Receptor
Adrenergic Receptor
T0007 Atenolol Atenolol is a selective β1 receptor antagonist.
T0007L (R)-(+)-Atenolol (R)-(+)-Atenolol is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.
T0031 Ziprasidone hydrochloride monohydrate Ziprasidone(CP88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity。
T0031L Ziprasidone hydrochloride Ziprasidone (hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T0031L2 Ziprasidone Ziprasidone is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T0042 Xylometazoline hydrochloride Xylometazoline Hydrochloride is an α-adrenoceptor agonist usually used as nasal decongestant.
T0076 Paliperidone Paliperidone(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabo
T0088 Urapidil hydrochloride Urapidil hydrochloride is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.
T0091 Alfuzosin hydrochloride Alfuzosin hydrochloride is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH).
T0101 Doxazosin mesylate Doxazosin mesylate(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.
T0103 Dipivefrin hydrochloride Dipivefrin that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.
T0115 Idazoxan hydrochloride Idazoxan hydrochloride is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity.
T0137 Mirtazapine Mirtazapine is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminot
T0143 (±)-Bisoprolol hemifumarate Bisoprolol, a selective beta-1 adrenergic receptor antagonist, selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby with antihyperten
T0151 Efloxate Efloxate, a vasodilator, is utilized in the treatment of chronic coronary insufficiency.
T0154 Nebivolol hydrochloride Nebivolol hydrochloride is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE s
T0162 Quetiapin Quetiapine is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is though
T0165 Urapidil Urapidil, a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist.
T0172 Maprotiline hydrochloride Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effect
T0173 Nylidrin hydrochloride Nylidrin hydrochloride was an effective inhibitor of the IgG1-mediated release of histamine from passively sensitized guinea pig lung slices, and of the IgE-mediated release of his
T0185 Escitalopram Escitalopram is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics an
T0197 Terazosin hydrochloride Terazosin, a selective alpha1-antagonist, can treat the benign prostatic hyperplasia (BPH). It also can lower blood pressure, so it is a drug of choice for patients with prostate e
T0210 Tamsulosin hydrochloride Tamsulosin Hydrochloride is the hydrochloride salt of tamsulosin, a sulfonamide derivative with α1 adrenergic antagonist activity.
T0226 Betaxolol hydrochloride Betaxolol is a cardioselective beta-blocker used in the treatment of hypertension. Betaxolol has not been linked to instances of clinically apparent drug induced liver injury.
T0248 Clorprenaline hydrochloride Clorprenaline Hydrochloride is a beta-2 adrenergic agonist with bronchodilator activity.
T0277 Orciprenaline sulfate Orciprenaline sulfate is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.
T0279 Metaraminol bitartrate Metaraminol bitartrate is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOT
T0290 Tizanidine hydrochloride Tizanidine hydrochloride, an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons.
T0317 Buflomedil hydrochloride Buflomedil hydrochloride, a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease.
T0324 Isoxsuprine hydrochloride Isoxsuprine hydrochloride is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
T0342 Carvedilol phosphate Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti
T0348 Labetalol hydrochloride Labetalol hydrochloride, a salicylamide derivative, is a non-cardioselective blocker of β-adrenergic receptors and α1-adrenergic receptors.
T0351 Risperidal Risperidone is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.
T0365 Thioridazine hydrochloride Thioridazine, an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
T0394 Moxisylyte hydrochloride Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease.
T0397 Tetryzoline Tetrahydrozoline, an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular
T0445 Promethazine Tafluprost(AFP-168) is an analogue of anti-glaucoma prostaglandin (PG) .
T0445L Promethazine hydrochloride Promethazine HCl(NSC-231688), the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5-
T0446 Naphazoline hydrochloride Naphazoline hydrochloride is an adrenergic vasoconstrictor agent used as a decongestant.
T0447 Carvedilol Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti
T0453 Phenylephrine hydrochloride Phenylephrine hydrochloride is a selective agonist of the α1-adrenergic receptor.
T0455 Clozapine Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacol
T0475 Timolol Maleate Timolol is a nonselective beta-adrenergic receptor blocker that is widely used for the therapy of hypertension, angina pectoris and prevention of vascular headaches.
T0483 Sotalol hydrochloride Sotalol Hydrochloride is the hydrochloride salt form of sotalol, an ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties.
T0487 Metoprolol tartrate Metoprolol Tartrate is a blocker of the cardioselective β-adrenergic receptor.
T0696 Naftopidil Naftopidil (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker.
T0735 Pindolol Pindolol is a moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing
T0766 Promazine hydrochloride Promazine hydrochloride is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed be
T0783 Mianserin hydrochloride Mianserin hydrochloride is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. It may ca
T0812 Propranolol hydrochloride Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTE
T0852 Carbazochrome sodium sulfonate Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for the treatment of hemorrhoids.
T0871 Noradrenaline bitartrate Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors. Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that
T0948 Adrenalone hydrochloride Adrenalone hydrochloride, a selective α1-adrenoceptor agonist, is used as a topical hemostatic and vasoconstrictor and used to extend the effect of local anesthetics.
T0970 Anisodamine Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
T0991 Desipramine hydrochloride Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), desipramine hydrochl
T0993 Methoxamine hydrochloride An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
T1012 Acebutolol hydrochloride Acebutolol acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol Hydrochloride is
T10364 Arbutamine Arbutamine is a short-acting synthetic potent nonselective β-adrenoceptor agonist that increases cardiac contractility, heart rate, and systolic blood pressure.
T1045 Trimipramine maleate Trimipramine maleate appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its acti
T1050 Prazosin hydrochloride Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin
T1056 Isoprenaline hydrochloride Isoproterenol is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.
T1064 Noradrenaline bitartrate monohydrate Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.
T1071L DL-Adrenaline Hydrochloride DL-Adrenaline Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing activities.
T1071L2 DL-Adrenalin DL-Epinephrine(DL-Adrenaline) is a hormone and a neurotransmitter.
T1073 Dronedarone hydrochloride Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
T10778 CGP 20712 A CGP 20712 A (CGP 20712 mesylate) is a highly selective antagonist of β1-adrenoceptor (IC50: 0.7 nM). It shows ~10,000-fold selectivity over β2-adrenoceptors.
T1090 Perphenazine Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
T10952 Dabuzalgron Dabuzalgron is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence. Dabuzaron prevents cardiotoxicity caused by doxorubicin by mainta
T11010 Detomidine carboxylic acid Detomidine carboxylic acid is the main urine metabolite of detomidine. Detomidine is a synthetic α2-adrenergic agonist and an animal analgesic. Detomidine also has heart and breat
T11015 Midaglizole hydrochloride Midaglizole hydrochloride (DG5128) is a preferred α2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for α2-adrenoceptor (pKi = 6.28) 7.4 times highe
T11036 Diacetolol D7 Diacetolol D7 is deuterium-labeled diacetone Roller. Diacetol is the main metabolite of Acetolol. Diacetololβ-adrenoceptor shielding and anti-arrhythmic agent.
T11286 Fiduxosin Fiduxosin is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.
T11318 Dopexamine hydrochloride Dopexamine hydrochloride is a β2-adrenergic receptor agonist.
T1132 Nicergoline Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
T1139 Salbutamol Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monoph
T1158 Phenoxybenzamine hydrochloride Phenoxybenzamine Hydrochloride is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory prope
T11786 KUL 7211 racemate KUL 7211 is a selective β-adrenoceptor agonist. KUL 7211 racemate is the racemate of KUL 7211.
T11894 Lusaperidone Lusaperidone is an α2 adrenergic receptor antagonist, with Kis of 0.13 and 0.15 nM for α2A and α2C, respectively.
T1203 Nadolol Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. Nadolol competitively blocks beta-1 adrenergic receptors located in the h
T1215 Nicardipine hydrochloride Nicardipine Hydrochloride is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine
T12343 Benzquinamide Benzquinamide is an antiemetic, can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) (Ki of 1,365, 691, and 545 nM, respectively).
T1239 Indacaterol maleate Indacaterol Maleate is an ultra-long-acting β-adrenoceptor agonist.
T12402 Penbutolol sulfate Penbutolol sulfate is able to bind to both β2-adrenergic receptor and β1-adrenergic receptor, thus making it a non-selective β blocker.
T12444 Phentolamine Analogue 1 Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of α-adrenergic.
T1247 Clonidine hydrochloride Clonidine is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide scale use for many
T12643 (R)-Terazosin (R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM
T1275 Phentolamine mesilate Phentolamine mesylate is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAU
T12815 (S)-Terazosin (S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity antagonist of α-adrenoceptor(α1a, α1b and α1d-adrenoceptor with Ki values of 3
T1282 Carteolol hydrochloride Carteolol Hydrochloride is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 rec
T1287 Synephrine Synephrine is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.
T12970 Solabegron Solabegron is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for
T13016 SR59230A SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively).
T1327 Nortriptyline hydrochloride Nortriptyline hydrochloride is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depres
T13285 Vatinoxan hydrochloride Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.
T13403 ZK-90055 hydrochloride ZK-90055 hydrochloride is an agonist of β2 adrenergic receptor.
T13470 (±)-Methotrimeprazine (D6) (±)-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is an antagonist of D3 dopamine and Histamine H1 receptor.
T13804 OPC-28326 OPC-28326 is a selective peripheral vasodilator and an α2-adrenergic receptor angatonist(α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively).
T1415 Gemfibrozil Gemfibrozil interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotei
T14287 Ancarolol Ancarolol is a blocking agent of beta-adrenergic.
T1433 Ritodrine hydrochloride Ritodrine binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine is a
T1446 Bambuterol hydrochloride Bambuterol, a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.
T1459 Cisatracurium besylate Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration.
T1496 Amiodarone hydrochloride Amiodarone hydrochloride is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and
T1500 Xylazine hydrochloride Xylazine hydrochloride is an adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in veterinary medicine
T1503 Esmolol hydrochloride Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically a
T1504 Silodosin Silodosin is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist.
T15042 D2343 D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.
T1539 Iloperidone Iloperidone is an atypical antipsychotic agent that is used for treatment of schizophrenia.
T1540 Doxepin hydrochloride Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is
T1567 Olanzapine Olanzapine is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T1577 Midodrine hydrochloride Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the a
T1584 Terbutaline Sulfate Terbutaline sulfate is a selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.
T15943 M443 M443 is an irreversible and specific MRK inhibitor (IC50<125 nM).
T1619 Trazodone hydrochloride Trazodone hydrochloride is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and o
T1632 Amitraz AMITRAZ is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mange in dogs.
T1671 Mirabegron Mirabegron is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.
T16759 Ritanserin Ritanserin is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM).
T16769 Ro 363 RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is
T1680 Tolazoline hydrochloride Tolazoline is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn.
T1696 2-(1-Piperazinyl)pyrimidine 2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug.
T1738 Taxifolin Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.
T1769 Pardoprunox Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the treatment of Early
T21066 Norepinephrine bitartrate salt Norepinephrine bitartrate salt is an adrenergic neurotransmitter.
T21147 Clenbuterol Clenbuterol is a substituted phenylaminoethanol that has β2 adrenomimetic properties at very low doses, and is used as a bronchodilator in asthma.
T2142 Yohimbine hydrochloride Yohimbine hydrochloride is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
T21446 Rotigotine Hydrochloride Rotigotine Hydrochloride, a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is ab
T2150 Guanfacine hydrochloride Guanfacine hydrochloride is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
T2226 Pergolide mesylate salt PERGOLIDE MESYLATE is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEAR
T22406 Prazosin Prazosin, an α1-blocker, acts as an inverse agonist at alpha-1 adrenergic receptors and is used to treat hypertension.
T2306 Brexpiprazole Brexpiprazole is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.
T2320 Indacaterol Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.
T23283 RX 821002 hydrochloride α2-adrenoceptor antagonist
T2524 Dexmedetomidine Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is
T2535 Ivabradine hydrochloride Ivabradine hydrochloride is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-act
T2546 Pimozide Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the centr
T2547 Droxidopa Droxidopa is an orally available prodrug of norepinephrine that is used in the treatment of symptomatic orthostatic hypotension due to neurogenic causes of autonomic failure.
T2580 Formoterol Arformoterol is an adrenergic β-2 receptor agonist with a prolonged duration of action. It is used to manage asthma and in the treatment of chronic obstructive pulmonary disease.
T2889 Isoferulic acid 3-Hydroxy-4-methoxycinnamic Acid exhibits hypoglycemic properties.
T3033 Deoxycorticosterone acetate Desoxycorticosterone acetate is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
T3046 BMY 7378 dihydrochloride BMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
T3165 Metoprolol Succinate Metoprolol succinate is a selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
T3232 Higenamine Hydrochloride Higenamine(Hydrochloride) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein–coupled receptors,
T3277 Tulobuterol hydrochloride Tulobuterol hydrochloride is a long-acting beta2-adrenergic receptor agonist.
T3278 Piribedil Piribedil is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T3284 Carazolol Carazolol is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the β-adrenergic receptor.
T3457 Olodaterol Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in
T3996 Dapiprazole Hydrochloride Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins
T4429 Rauwolscine hydrochloride Rauwolscine, a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes both
T4526 Piperoxan hydrochloride Piperoxan hydrochloride is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered.
T4548 Procaterol hydrochloride Short-acting β2-adrenergic receptor agonist used to treat asthma.
T4560 Alprenolol Alprenolol is a non-selective β-adrenergic receptor (β-AR) antagonist that is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B.
T4963 Higenamine Higenamine is a novel α1 -adrenoceptor antagonist.
T4983 Isoetharine mesylate salt Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. it also is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression.
T4S0998 Trifolirhizin Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses pote
T5028 Landiolol hydrochloride Landiolol is an ultra-short-acting β1 selective adrenoceptor antagonist.
T5035 Methoxyphenamine Hydrochloride Methoxyphenamine is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.
T5105 1-(2-Pyridyl)piperazine 1-(2-Pyridyl)piperazine is a selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metabolite of Azaperone
T5134 Vilanterol trifenatate Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively)
T5159 BI 1744 hydrochloride Olodaterol is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adren
T5327 Amezinium (methylsulfate) Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.
T5450 DL-071-IT DL 071-IT is a potent non-selective beta-adrenoceptor antagonist. DL 071 IT showed intrinsic sympathomimetic activity and weak membrane stabilizing activity.
T5471 GUANABENZ GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.
T5S2178 Fargesin 1. Fargesin as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyp
T6241 Quetiapine Fumarate Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T6408 Betaxolol Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
T6422 Brimonidine Tartrate Brimonidine tartrate is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucom
T6464 Detomidine HCl Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.
T6466 Dexmedetomidine HCl Dexmedetomidine hydrochloride is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of
T6505 Formoterol Hemifumarate Formoterol Hemifumarate, an effective, specific and long-acting β2-adrenoceptor agonist, is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma.
T6519 Gramine Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1
T6522 Guanabenz Acetate Guanabenz Acetate is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25, 7.01 and ~5,
T6565 Levobetaxolol HCl Levobetaxolol hydrochloride is a beta-adrenergic receptor inhibitor (beta blocker), used to lower the pressure in the eye in treating conditions such as glaucoma.
T6579 Medetomidine HCl Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
T6600 Naftopidil DiHCl Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
T6652 Salbutamol Sulfate Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.
T6653 Salmeterol Xinafoate Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary dis
T6662 Scopine Scopine, the metabolite of anisodine, is an α1-adrenergic receptor agonist used in the therapy of acute circulatory shock.
T6663 Scopine HCl Scopine HCl salt is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.
T6688 Synephrine HCl SynephrineHCl (Oxedrine, p-Synephrine) is an agonist that acts on sympathomimetic α-adrenergic receptor (AR).
T6701 Terazosin hydrochloride dihydrate Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH).
T6703 Tetrahydrozoline HCl Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity.
T6765 Atipamezole hydrochloride Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochlori
T6766 Atipamezole Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.
T6860 ICI-118551 Hydrochloride ICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.
T6872 L755507 L755507 is an effective, selective agonist of β3-AR(IC50=35 nM).
T7044 Norepinephrine Norepinephrine can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growt
T7045 Clonidine Clonidine is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many
T7046 Xylazine Xylazine is α2-adrenergic receptor agonist.
T7065 Tizanidine Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons.
T7079 Batefenterol Batefenterol (GSK961081, TD-5959) is a muscarinic receptor antagonist and β2-adrenoceptor agonist. It displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor (Ki:1.4/
T7160 Lofexidine Lofexidine is a selective α2-receptor agonist, Lofexidine reduces narcotic withdrawal symptoms.
T7164 Levalbuterol tartrate Levosalbutamol tartrate is the β2-adrenergic receptor agonist,and is used to treatment of asthma.
T8143 Bevantolol hydrochloride Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
T8149 Dobutamine (hydrochloride) Dobutamine (hydrochloride) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.
T8304 Anisodamine Hydrobromide Anisodamine Hydrobromide is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
T8348 Phentolamine Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
T8358 Fenoterol Fenoterol is an  agonist of  β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication.
T8580 Bupranolol Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
T8595 Practolol Practolol is a selective β-adrenoceptor blocker.
T8663 nifenalol.HCl Nifenalol is a antagonist of β-adrenergic receptor.
T8696 Propranolol HCl Propranolol hydrochloride is a blocker of β1 and β2 adrenergic receptor
T8738 LUN42518 HCl 47142-51-8(free base) LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.
T8810 Terbutaline Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol
T8899 Metipranolol Metipranolol is a β-adrenergic receptor antagonist that is given orally for the treatment of hypertension and also applied topically to the cornea for treating glaucoma.
TCS2185 Yohimbine Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM)
TN1797 Isorhoifolin Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing
TN1922 Meranzin hydrate Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-i
TN2267 Tetrahydroalstonine Tetrahydroalstonine and Raubasine preferentially block the pressor responses of post-synaptic alpha-adrenergic receptor activation due to exogenous and endogenouse noradrenaline, r
TN3364 Agrimonolide Agrimonolide is a potential α1 adrenergic receptor antagonist, it exerts anti-inflammatory activity, at least in part, via suppressing LPS-induced activation of JAK-STATs and p38
TN3368 Akuammigine Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68.
TN3507 beta-Yohimbine Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it
TN4323 Isorauhimbine 3-Epi-alpha-yohimbine(Isorauhimbine) has alpha adrenoceptor blocking activities,it also has cardiovascular effects.
TN4882 Quinine HCl Quinine HCl produces alpha-adrenergic blockade. Quinine modifies catecholamine- and calcium-induced myocardial contractile force responses.
TN5061 Stephanine l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine sh
TP1238L ACTH 1-14 acetate(25696-21-3 free base) ACTH (1-14) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and
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