| T0007 |
Atenolol |
Atenolol is a selective β1 receptor antagonist. |
| T0031 |
Ziprasidone hydrochloride monohydrate |
Ziprasidone(CP88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity. |
| T0031L |
Ziprasidone hydrochloride |
Ziprasidone (hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity. |
| T0031L2 |
Ziprasidone |
Ziprasidone is an a typical antipsychotic used in the treatment of schizophrenia and bipolar disorder. Use of ziprasidone has not been consistently associated with serum enzyme |
| T0042 |
Xylometazoline hydrochloride |
Xylometazoline Hydrochloride is an α-adrenoceptor agonist usually used as nasal decongestant. |
| T0076 |
Paliperidone |
Paliperidone(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabo |
| T0088 |
Urapidil hydrochloride |
Urapidil hydrochloride is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist. |
| T0091 |
Alfuzosin hydrochloride |
Alfuzosin hydrochloride is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH). |
| T0101 |
Doxazosin mesylate |
Doxazosin mesylate(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors. |
| T0103 |
Dipivefrin hydrochloride |
Dipivefrin that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma. |
| T0115 |
Idazoxan hydrochloride |
Idazoxan hydrochloride is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity. |
| T0137 |
Mirtazapine |
Mirtazapine is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminot |
| T0143 |
(±)-Bisoprolol hemifumarate |
Bisoprolol，a selective beta-1 adrenergic receptor antagonist，selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart，thereby with antihyper |
| T0154 |
Nebivolol hydrochloride |
Nebivolol hydrochloride is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE s |
| T0162 |
Quetiapin |
Quetiapine is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is though |
| T0165 |
Urapidil |
Urapidil, a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist. |
| T0172 |
Maprotiline hydrochloride |
Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effect |
| T0173 |
Nylidrin hydrochloride |
Nylidrin hydrochloride was an effective inhibitor of the IgG1-mediated release of histamine from passively sensitized guinea pig lung slices, and of the IgE-mediated release of his |
| T0197 |
Terazosin hydrochloride |
Terazosin, a selective alpha1-antagonist, can treat the benign prostatic hyperplasia (BPH). It also can lower blood pressure, so it is a drug of choice for patients with prostate e |
| T0210 |
Tamsulosin hydrochloride |
Tamsulosin Hydrochloride is the hydrochloride salt of tamsulosin, a sulfonamide derivative with α1 adrenergic antagonist activity. |
| T0226 |
Betaxolol hydrochloride |
Betaxolol is a cardioselective beta-blocker used in the treatment of hypertension. Betaxolol has not been linked to instances of clinically apparent drug induced liver injury. |
| T0248 |
Clorprenaline hydrochloride |
Clorprenaline Hydrochloride is a beta-2 adrenergic agonist with bronchodilator activity. |
| T0277 |
Orciprenaline sulfate |
Orciprenaline sulfate is a beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM. |
| T0279 |
Metaraminol bitartrate |
Metaraminol bitartrate is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOT |
| T0290 |
Tizanidine hydrochloride |
Tizanidine hydrochloride, an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons. |
| T0317 |
Buflomedil hydrochloride |
Buflomedil hydrochloride, a vasodilator, is used in therapy of claudication or the symptoms of the peripheral arterial disease. |
| T0324 |
Isoxsuprine hydrochloride |
Isoxsuprine hydrochloride is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. |
| T0342 |
Carvedilol phosphate |
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti |
| T0348 |
Labetalol hydrochloride |
Labetalol hydrochloride, a salicylamide derivative, is a non-cardioselective blocker of β-adrenergic receptors and α1-adrenergic receptors. |
| T0351 |
Risperidal |
Risperidone is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent. |
| T0365 |
Thioridazine hydrochloride |
Thioridazine, an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity. |
| T0394 |
Moxisylyte hydrochloride |
Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. |
| T0397 |
Tetryzoline |
Tetrahydrozoline, an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular |
| T0445 |
Promethazine |
Tafluprost(AFP-168) is an analogue of anti-glaucoma prostaglandin (PG) . |
| T0445L |
Promethazine hydrochloride |
Promethazine HCl(NSC-231688), the first-generation antihistamine, is a strong antagonist of the H1 receptor and a moderate antagonist of the mACh receptor, moderate affinity for 5- |
| T0446 |
Naphazoline hydrochloride |
Naphazoline hydrochloride is an adrenergic vasoconstrictor agent used as a decongestant. |
| T0447 |
Carvedilol |
Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimeti |
| T0453 |
Phenylephrine hydrochloride |
Phenylephrine hydrochloride is a selective agonist of the α1-adrenergic receptor. |
| T0455 |
Clozapine |
Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacol |
| T0475 |
Timolol Maleate |
Timolol is a nonselective beta-adrenergic receptor blocker that is widely used for the therapy of hypertension, angina pectoris and prevention of vascular headaches. |
| T0483 |
Sotalol hydrochloride |
Sotalol Hydrochloride is the hydrochloride salt form of sotalol, an ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties. |
| T0487 |
Metoprolol tartrate |
Metoprolol Tartrate is a blocker of the cardioselective β-adrenergic receptor. |
| T0696 |
Naftopidil |
Naftopidil (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker. |
| T0766 |
Promazine hydrochloride |
Promazine hydrochloride is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed be |
| T0783 |
Mianserin hydrochloride |
Mianserin hydrochloride is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. It may ca |
| T0812 |
Propranolol hydrochloride |
Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTE |
| T0871 |
Noradrenaline bitartrate |
Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors. Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that |
| T0948 |
Adrenalone hydrochloride |
Adrenalone hydrochloride, a selective α1-adrenoceptor agonist, is used as a topical hemostatic and vasoconstrictor and used to extend the effect of local anesthetics. |
| T0970 |
Anisodamine |
Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock. |
| T0991 |
Desipramine hydrochloride |
Desipramine Hydrochloride a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), desipramine hydrochl |
| T0993 |
Methoxamine hydrochloride |
An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION. |
| T1012 |
Acebutolol hydrochloride |
Acebutolol acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol Hydrochloride is |
| T1045 |
Trimipramine maleate |
Trimipramine maleate appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its acti |
| T1050 |
Prazosin hydrochloride |
Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin |
| T1056 |
Isoprenaline hydrochloride |
Isoproterenol is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties. |
| T1064 |
Noradrenaline bitartrate monohydrate |
Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator. |
| T1071L |
DL-Adrenaline Hydrochloride |
DL-Adrenaline Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing activities. |
| T1071L2 |
DL-Adrenalin |
DL-Epinephrine(DL-Adrenaline) is the racemate of epinephrine. |
| T1073 |
Dronedarone hydrochloride |
Dronedarone hydrochloride is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation. |
| T1132 |
Nicergoline |
Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins. |
| T1139 |
Salbutamol |
Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monopho |
| T1158 |
Phenoxybenzamine hydrochloride |
Phenoxybenzamine Hydrochloride is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory prope |
| T1203 |
Nadolol |
Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. Nadolol competitively blocks beta-1 adrenergic receptors located in the h |
| T1215 |
Nicardipine hydrochloride |
Nicardipine Hydrochloride is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine |
| T1239 |
Indacaterol maleate |
Indacaterol Maleate is an ultra-long-acting β-adrenoceptor agonist. |
| T1247 |
Clonidine hydrochloride |
Clonidine is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide scale use for many |
| T1275 |
Phentolamine mesilate |
Phentolamine mesylate is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAU |
| T1282 |
Carteolol hydrochloride |
Carteolol Hydrochloride is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 rec |
| T1287 |
Synephrine |
Synephrine is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma. |
| T1327 |
Nortriptyline hydrochloride |
Nortriptyline hydrochloride is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depres |
| T1433 |
Ritodrine hydrochloride |
Ritodrine binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine is a |
| T1446 |
Bambuterol hydrochloride |
Bambuterol, a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma. |
| T1459 |
Cisatracurium besylate |
Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. |
| T1496 |
Amiodarone hydrochloride |
Amiodarone hydrochloride is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and |
| T1500 |
Xylazine hydrochloride |
Xylazine hydrochloride is an adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in veterinary medicine |
| T1503 |
Esmolol hydrochloride |
Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension. Esmolol has not been linked to instances of clinically a |
| T1504 |
Silodosin |
Silodosin is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist. |
| T1539 |
Iloperidone |
Iloperidone is an atypical antipsychotic agent that is used for treatment of schizophrenia. |
| T1540 |
Doxepin hydrochloride |
Doxepin Hydrochloride is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is |
| T1567 |
Olanzapine |
Olanzapine is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. |
| T1577 |
Midodrine hydrochloride |
Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the a |
| T1584 |
Terbutaline Sulfate |
Terbutaline sulfate is a selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic. |
| T1619 |
Trazodone hydrochloride |
Trazodone hydrochloride is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and o |
| T1632 |
Amitraz |
AMITRAZ is a white monoclinic crystals. Melting point 187-189°F (86-87°C). Insoluble in water. Used as an acaricide, insecticide and treatment of demodectic mange in dogs. |
| T1671 |
Mirabegron |
Mirabegron is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome. |
| T1680 |
Tolazoline hydrochloride |
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn. |
| T1696 |
2-(1-Piperazinyl)pyrimidine |
2-(1-Piperazinyl)pyrimidine is used as an anti-anxiety drug. |
| T1738 |
Taxifolin |
Taxifolin is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on. |
| T1769 |
Pardoprunox |
Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the treatment of Early |
| T2142 |
Yohimbine hydrochloride |
Yohimbine hydrochloride is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION. |
| T2150 |
Guanfacine hydrochloride |
Guanfacine hydrochloride is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS. |
| T2306 |
Brexpiprazole |
Brexpiprazole is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors. |
| T2320 |
Indacaterol |
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist. |
| T2524 |
Dexmedetomidine |
Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is |
| T2535 |
Ivabradine hydrochloride |
Ivabradine hydrochloride is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-act |
| T2547 |
Droxidopa |
Droxidopa is an orally available prodrug of norepinephrine that is used in the treatment of symptomatic orthostatic hypotension due to neurogenic causes of autonomic failure. |
| T2580 |
Formoterol |
Arformoterol is an adrenergic β-2 receptor agonist with a prolonged duration of action. It is used to manage asthma and in the treatment of chronic obstructive pulmonary disease. |
| T3046 |
BMY 7378 dihydrochloride |
BMY-7378, α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor. |
| T3165 |
Metoprolol Succinate |
Metoprolol succinate is a selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS. |
| T3277 |
Tulobuterol hydrochloride |
Tulobuterol hydrochloride is a long-acting beta2-adrenergic receptor agonist. |
| T3278 |
Piribedil |
Piribedil is a dopamine D2 agonist, used in the treatment of Parkinson's disease. |
| T3284 |
Carazolol |
Carazolol is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the β-adrenergic receptor. |
| T3457 |
Olodaterol |
Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in |
| T3996 |
Dapiprazole Hydrochloride |
Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins |
| T6241 |
Quetiapine Fumarate |
Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression. |
| T6408 |
Betaxolol |
Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma. |
| T6422 |
Brimonidine Tartrate |
Brimonidine tartrate is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucom |
| T6464 |
Detomidine HCl |
Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors. |
| T6466 |
Dexmedetomidine HCl |
Dexmedetomidine hydrochloride is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of |
| T6505 |
Formoterol Hemifumarate |
Formoterol Hemifumarate, an effective, specific and long-acting β2-adrenoceptor agonist, is utilized in the treatment of chronic obstructive pulmonary disease(COPD) and asthma. |
| T6522 |
Guanabenz Acetate |
Guanabenz Acetate is a specific agonist of adrenergic receptor. The pEC50 for α2a-adrenergic receptor, α2b-adrenergic receptor and α2c-adrenergic receptor is 8.25, 7.01 and ~5, |
| T6565 |
Levobetaxolol HCl |
Levobetaxolol hydrochloride is a beta-adrenergic receptor inhibitor (beta blocker), used to lower the pressure in the eye in treating conditions such as glaucoma. |
| T6579 |
Medetomidine HCl |
Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor. |
| T6600 |
Naftopidil DiHCl |
Naftopidil DiHCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively. |
| T6652 |
Salbutamol Sulfate |
Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM. |
| T6662 |
Scopine |
Scopine, the metabolite of anisodine, is an α1-adrenergic receptor agonist used in the therapy of acute circulatory shock. |
| T6688 |
Synephrine HCl |
SynephrineHCl (Oxedrine, p-Synephrine) is an agonist that acts on sympathomimetic α-adrenergic receptor (AR). |
| T6701 |
Terazosin hydrochloride dihydrate |
Terazosin HCl is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH). |
| T6703 |
Tetrahydrozoline HCl |
Tetrahydrozoline HCl is an imidazoline derivative with alpha receptor agonist activity. |
| T6765 |
Atipamezole hydrochloride |
Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochlori |
| T6766 |
Atipamezole |
Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. |
| T6860 |
ICI-118551 Hydrochloride |
ICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. |
| T6872 |
L755507 |
L755507 is an effective, selective agonist of β3-AR（IC50=35 nM）. |
| T4429 |
Rauwolscine hydrochloride |
Rauwolscine, a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes both |
| T2226 |
Pergolide mesylate salt |
PERGOLIDE MESYLATE is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEAR |
| T5S2178 |
Fargesin |
1. Fargesin as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyp |
| T4548 |
Procaterol hydrochloride |
Short-acting β2-adrenergic receptor agonist used to treat asthma. |
| T7046 |
Xylazine |
Xylazine is α2-adrenergic receptor agonist. |
| T7079 |
Batefenterol |
Batefenterol (GSK961081, TD-5959) is a muscarinic receptor antagonist and β2-adrenoceptor agonist. It displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor (Ki:1.4/ |
| T4526 |
Piperoxan hydrochloride |
Piperoxan hydrochloride is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered. |
| T4560 |
Alprenolol |
Alprenolol is a non-selective β-adrenergic receptor (β-AR) antagonist that is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B. |
| T4S0998 |
Trifolirhizin |
Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses pote |
| T4983 |
Isoetharine mesylate salt |
Isoetharine Mesylate Salt is a β-adrenergic receptor agonist. it also is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression. |
| T5105 |
1-(2-Pyridyl)piperazine |
1-(2-Pyridyl)piperazine is a selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metabolite of Azaperone |
| T5028 |
Landiolol hydrochloride |
Landiolol is an ultra-short-acting β1 selective adrenoceptor antagonist. |
| T5035 |
Methoxyphenamine Hydrochloride |
Methoxyphenamine is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator. |
| T4963 |
Higenamine |
Higenamine is a novel α1 -adrenoceptor antagonist. |
| T7045 |
Clonidine |
Clonidine is a centrally active alpha-adrenergic agonist used predominantly as an antihypertensive agent, usually in combination with other agents. Despite wide-scale use for many |
| T5159 |
BI 1744 hydrochloride |
Olodaterol is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adre |
| T5327 |
Amezinium (methylsulfate) |
Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake. |
| T6519 |
Gramine |
Gramine, a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1 |
| T5450 |
DL-071-IT |
DL 071-IT is a potent non-selective beta-adrenoceptor antagonist. DL 071 IT showed intrinsic sympathomimetic activity and weak membrane stabilizing activity. |
| T5471 |
GUANABENZ |
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist. |
| T7160 |
Lofexidine |
Lofexidine is a selective α2-receptor agonist, Lofexidine reduces narcotic withdrawal symptoms. |
| T7164 |
Levalbuterol tartrate |
Levosalbutamol tartrate is the β2-adrenergic receptor agonist,and is used to treatment of asthma. |
| T1090 |
Perphenazine |
Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. |
| T2546 |
Pimozide |
Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the centr |
| T7044 |
Norepinephrine |
Norepinephrine can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growt |
| T1415 |
Gemfibrozil |
Gemfibrozil interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotei |
| TCS2185 |
Yohimbine |
Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM) |
| T8304 |
Anisodamine Hydrobromide |
Anisodamine Hydrobromide is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock. |
| T8149 |
Dobutamine (hydrochloride) |
Dobutamine (hydrochloride) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects. |
| T8143 |
Bevantolol hydrochloride |
Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension. |
| T8358 |
Fenoterol |
Fenoterol is an agonist of β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication. |
| TN1797 |
Isorhoifolin |
Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing |
| TN1922 |
Meranzin hydrate |
Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-i |
| TN2267 |
Tetrahydroalstonine |
Tetrahydroalstonine and Raubasine preferentially block the pressor responses of post-synaptic alpha-adrenergic receptor activation due to exogenous and endogenouse noradrenaline, r |
| T8348 |
Phentolamine |
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist |
| T13804 |
OPC-28326 |
OPC-28326 is a selective peripheral vasodilator and an α2-adrenergic receptor angatonist(α2A-, α2B- and α2C-adrenoceptors with Ki of 2040, 285, and 55 nM, respectively). |
| T12343 |
Benzquinamide |
Benzquinamide is an antiemetic, can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) (Ki of 1,365, 691, and 545 nM, respectively). |
| T11010 |
Detomidine carboxylic acid |
Detomidine carboxylic acid is the main urine metabolite of detomidine. Detomidine is a synthetic α2-adrenergic agonist and an animal analgesic. Detomidine also has heart and breat |
| T11015 |
Midaglizole hydrochloride |
Midaglizole hydrochloride (DG5128) is a preferred α2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for α2-adrenoceptor (pKi = 6.28) 7.4 times highe |
| T11036 |
Diacetolol D7 |
Diacetolol D7 is deuterium-labeled diacetone Roller. Diacetol is the main metabolite of Acetolol. Diacetololβ-adrenoceptor shielding and anti-arrhythmic agent. |
| T13016 |
SR59230A |
SR59230A is a selective, and blood-brain barrier penetrating antagonist of β3-adrenergic receptor(IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively). |
| T5134 |
Vilanterol trifenatate |
Vilanterol trifenatate is a long-acting agonist of β2-adrenoceptor (β2-AR) with inherent 24-hour activity(β2-AR, β1-AR and β3-AR pEC50s of 10.37, 6.98 and 7.36, respectively) |
| T7065 |
Tizanidine |
Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. |
| T14287 |
Ancarolol |
Ancarolol is a blocking agent of beta-adrenergic. |
| T12643 |
(R)-Terazosin |
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM |
| T10364 |
Arbutamine |
Arbutamine is a short-acting synthetic potent nonselective β-adrenoceptor agonist that increases cardiac contractility, heart rate, and systolic blood pressure. |
| T15042 |
D2343 |
D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor. |
| T12815 |
(S)-Terazosin |
(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity antagonist of α-adrenoceptor(α1a, α1b and α1d-adrenoceptor with Ki values of 3 |
| T11286 |
Fiduxosin |
Fiduxosin is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively. |
| T13285 |
Vatinoxan hydrochloride |
Vatinoxan hydrochloride is an antagonist of peripheral α2 adrenergic receptor. |
| T10778 |
CGP 20712 A |
CGP 20712 A (CGP 20712 mesylate) is a highly selective antagonist of β1-adrenoceptor (IC50: 0.7 nM). It shows ~10,000-fold selectivity over β2-adrenoceptors. |
| T13403 |
ZK-90055 hydrochloride |
ZK-90055 hydrochloride is an agonist of β2 adrenergic receptor. |
| T13470 |
(±)-Methotrimeprazine (D6) |
(±)-Methotrimeprazine (D6) is the deuterium labeled Methotrimeprazine, which is an antagonist of D3 dopamine and Histamine H1 receptor. |
| T15943 |
M443 |
M443 is an irreversible and specific MRK inhibitor (IC50<125 nM). |
| T8366 |
Mitochonic acid 5 |
Mitochonic acid 5 is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has be |
| T11786 |
KUL 7211 racemate |
KUL 7211 is a selective β-adrenoceptor agonist. KUL 7211 racemate is the racemate of KUL 7211. |
| T16759 |
Ritanserin |
Ritanserin is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM). |
| T16769 |
Ro 363 |
RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is |
| T11894 |
Lusaperidone |
Lusaperidone is an α2 adrenergic receptor antagonist, with Kis of 0.13 and 0.15 nM for α2A and α2C, respectively. |
| T22406 |
Prazosin |
Prazosin, an α1-blocker, acts as an inverse agonist at alpha-1 adrenergic receptors and is used to treat hypertension. |
| T8580 |
Bupranolol |
Bupranolol is an antagonist of β2-adrenergic receptor，and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic. |
| T8595 |
Practolol |
Practolol is a selective β-adrenoceptor blocker. |
| TN3364 |
Agrimonolide |
Agrimonolide is a potential α1 adrenergic receptor antagonist, it exerts anti-inflammatory activity, at least in part, via suppressing LPS-induced activation of JAK-STATs and p38 |
| TN3368 |
Akuammigine |
Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. |
| TN3507 |
beta-Yohimbine |
Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it |
| TN4323 |
Isorauhimbine |
3-Epi-alpha-yohimbine(Isorauhimbine) has alpha adrenoceptor blocking activities,it also has cardiovascular effects. |
| TN4882 |
Quinine HCl |
Quinine HCl produces alpha-adrenergic blockade. Quinine modifies catecholamine- and calcium-induced myocardial contractile force responses. |
| TN5061 |
Stephanine |
l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine sh |
| T8663 |
nifenalol.HCl |
Nifenalol is a antagonist of β-adrenergic receptor. |
| T21147 |
Clenbuterol |
Clenbuterol is a substituted phenylaminoethanol that has β2 adrenomimetic properties at very low doses, and is used as a bronchodilator in asthma. |
| T21066 |
Norepinephrine bitartrate salt |
Norepinephrine bitartrate salt is an adrenergic neurotransmitter. |
| T8696 |
Propranolol hydrochloride |
Propranolol hydrochloride is a blocker of β1 and β2 adrenergic receptor |
| T12444 |
Phentolamine Analogue 1 |
Phentolamine Analogue 1 is an analogue of phentolamine. Phentolamine is a nonselective antagonist of alpha-adrenergic. |
