| T0055L |
Glafenine Hydrochloride |
Glafenine Hydrochloride is an anti-inflammatory agent. |
| T0128 |
Vigabatrin |
Vigabatrin, an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate transaminase responsible for the catabolism of γ-aminobutyric acid. Off-label u |
| T0254 |
Probucol |
Probucol, an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate. |
| T0490 |
Chlorpropamide |
Chlorpropamide is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. |
| T0974 |
Novobiocin Sodium |
Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemica |
| T1050 |
Prazosin hydrochloride |
Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin |
| T1603 |
Glipizide |
Glipizide is a short-acting, second-generation sulfonylurea with hypoglycemic activity. |
| TQ0186 |
Ko 143 |
Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP). |
| T2590 |
Vismodegib |
Vismodegib is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM). |
| T8165 |
Erythrodiol |
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. |
| TN1804 |
Isosilybin A |
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) o |
| T18975 |
DIDS sodium salt |
DIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1. |
| T16122 |
MMAF sodium |
MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerizat |
| T4S2157 |
Campesterol |
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti |
