T22958
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Others
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Smoothened (Smo) receptor antagonist |
T71299
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M-25 is a Smoothened antagonist and inhibitor of the Hedgehog pathway. |
T10432L
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GluR
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AZD-8529 mesylate 是高度选择性的可口服mGluR2正向调节剂,EC50值为 285 nM。它在 20-25 M 时,对 mGluR1、3、4、5、6、7 和 8 亚型没有显示正变构调节剂反应。 |
T71297
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TT15 is an agonist of the GLP-1R. |
T18173
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Others
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m-PEG25-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T18174
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Others
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m-PEG25-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T18176
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Others
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m-PEG25-Propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T14197L
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Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist. |
T18175
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Others
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m-PEG25-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T38293
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Others
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4-CPPC 是一种巨噬细胞迁移抑制因子 2 (MIF-2; IC50= 27 μM) 的抑制剂。它对 MIF-2 的选择性高于 MIF-1 (IC50= 450 μM)。 当以 10 μM 浓度使用时,它在体外抑制 MIF-2,但不抑制 MIF-1,与 CD74 结合。 4-CPPC(5、10 和 25 μM)抑制原代人皮肤成纤维细胞中 MIF-2 诱导的 ERK1/2 磷酸化。 |