目录号 | 产品详情 | 靶点 | |
---|---|---|---|
T68415 | Others | ||
Tozasertib lactate is a potent and selective small-molecule inhibitor of the Aurora kinases which suppresses tumor growth by inducing apoptosis in tumor cells in which Aurora kinases are overexpressed. | |||
T2509 | Aurora Kinase Autophagy | ||
Tozasertib (MK-0457) 是一种 Aurora A/B/C 激酶抑制剂,Ki 值分别为 0.6、18和4.6 nM。它显示出对 190 多种不同激酶的选择性。 |