TN2252
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Dopamine Receptor
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Syrosingopine 是 MCT1和 MCT4双重抑制剂,对 MCT4 的效力高 60 倍,可防止乳酸和 H+ 流出。它是可口服抗高血压药物,联合二甲双胍具有研究癌症疾病的潜力。 |
T7460
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Monocarboxylate transporter
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α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) 是非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂,可抑制线粒体丙酮酸转运蛋白,Ki 值为 6.3 μM。它可作为基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质,可以促进肽离子化。 |
T39767
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AR-C141990 hydrochloride is a potent inhibitor of lactate transporters known as monocarboxylate transporters (MCTs). It has pK i values of 7.6 and 6.6 for MCT-1 and MCT-2, respectively. Additionally, this compound exhibits immunosuppressive properties and effectively inhibits the graft versus host response. |