目录号 | 产品详情 | 靶点 | |
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T60037 | DNA/RNA Synthesis | ||
SR15006 是 Krüppel 样因子 5 (KLF5) 抑制剂 (IC50 = 41.6 nM)。 | |||
T22667 | DNA/RNA Synthesis | ||
CID 5951923 是 KLF5 转录因子的抑制剂,IC50 为 603 nM。 | |||
T6894 | DNA/RNA Synthesis KLF | ||
ML264 (CID-51003603) 是抗肿瘤剂,能够特异性地抑制 Krüppel 样因子 5 表达。 | |||
T10352 | Apoptosis c-Myc KLF | ||
APTO-253 (LOR-253) 抑制 c-Myc 表达,稳定 G-四链体 DNA,并诱导急性髓细胞白血病细胞的细胞周期停滞和凋亡。 它通过诱导 KLF4 肿瘤抑制因子介导抗癌活性,具有抗关节炎活性。 |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPJ-01288 | KLF6 Protein, Human, Recombinant | Human | E. coli | ||
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.
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