T0025
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Dopamine Receptor
5-HT Receptor
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Haloperidol (Serenace) 是一种安定药,是一种dopamine D2 receptor 拮抗剂。 |
T25487
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Others
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Haloperidol decanoate (KD 16) 是一种典型的抗精神病药物,用作精神分裂症和情绪障碍的维持治疗,配制成用于肌肉注射的酯。 |
T37167
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Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing the human transporters). Reduced haloperidol (0.5 mg/kg) increases latency to paw withdrawal in mouse models of capsaicin- but not force-induced mechanical hypersensitivity. |
T11536
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Others
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Haloperidol D4' is deuterium-labeled haloperidol. Haloperidol is a dopamine D2 receptor antagonist. |
T11535
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Others
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Haloperidol D4 is deuterium-labeled haloperidol. |
T21669
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Haloperidol hydrochloride 是一种有效的 dopamine D2 receptor 拮抗剂,广泛用作抗精神病药 |
T62975
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Haloperidol lactate 是一种有效的抗精神病药。Haloperidol lactate 具有潜力进行精神障碍的研究。Haloperidol lactate 能够用于急性和慢性精神分裂症和多发性秽语综合征。 |
T0280
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Dopamine Receptor
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Spiperone (Spiropitan) 是多巴胺 D2、血清素5-HT1A 和血清素5-HT2A 拮抗剂。它是广泛使用的药理学工具。它具有研究神经系统疾病的潜力。 |
T33868
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Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) 是一种酰基氨基酸,可阻断主动脉收缩,可拮抗由氟哌啶醇诱发的口腔运动障碍。Palmitoyl glutamic acid 常常添加在化妆品中。 |
T29139
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VU0477886 is a potent mGlu4 positive allosteric modulator (PAM) with robust efficacy in a standard preclinical Parkinson's disease model, haloperidol-induced catalepsy (HIC). |