Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 2,360 | 5日内发货 | ||
500 μg | ¥ 9,490 | 5日内发货 | ||
1 mg | ¥ 15,800 | 5日内发货 |
生物活性 | Immobilized Human VEGF R2 at 0.5μg/ml (100μl/Well). Dose response curve for Anti-VEGFR2 Antibody, hFc Tag with the EC50 of 4.5ng/ml determined by ELISA. |
产品描述 | Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. |
种属 | Human |
表达系统 | HEK293 |
标签 | C-His-Avi |
蛋白编号 | P35968-1 |
别名 | VEGFR-21, Ly73, KRD1, VEGFR2, CD309, FLK1, VEGFR, KDR |
蛋白构建 | Recombinant Human VEGF R2/KDR Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Ala20-Glu764.[Accession |P35968-1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 86.2 kDa. Due to glycosylation, the protein migrates to 115-140 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. |
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VEGFR2/KDR Protein, Human, Recombinant (His & Avi) VEGFR 2 VEGFR-21 CD-309 Ly73 KRD 1 FLK 1 FLK-1 KRD1 CD 309 VEGFR2 KRD-1 CD309 VEGFR 21 FLK1 VEGFR KDR VEGFR-2 VEGFR21 recombinant recombinant-proteins proteins protein