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UBE2S Protein, Human, Recombinant (GST)

UBE2S Protein, Human, Recombinant (GST)

产品编号 TMPJ-01138
别名: UBE2S, Ubiquitin-Conjugating Enzyme E2-24 kDa, E2-EPF, E2EPF, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Protein Ligase S, Ubiquitin-Conjugating Enzyme E2 S, Ubiquitin Carrier Protein S

Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.

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UBE2S Protein, Human, Recombinant (GST)
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 620 5日内发货
500 μg ¥ 2,760 5日内发货
1 mg ¥ 3,950 5日内发货
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产品目录号及名称: UBE2S Protein, Human, Recombinant (GST) (TMPJ-01138)
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产品描述 Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.
种属 Human
表达系统 E. coli
标签 N-GST
蛋白编号 Q16763
别名 UBE2S, Ubiquitin-Conjugating Enzyme E2-24 kDa, E2-EPF, E2EPF, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Protein Ligase S, Ubiquitin-Conjugating Enzyme E2 S, Ubiquitin Carrier Protein S
氨基酸序列 Met1-Leu222
蛋白构建 Recombinant Human Ubiquitin-Conjugating Enzyme E2 S is produced by our E.coli expression system and the target gene encoding Met1-Leu222 is expressed with a GST tag at the N-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 50 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.

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Keywords

UBE2S Protein, Human, Recombinant (GST) UBE2S Ubiquitin-Conjugating Enzyme E2-24 kDa E2-EPF E2EPF Ubiquitin-Conjugating Enzyme E2-EPF5 Ubiquitin-Protein Ligase S Ubiquitin-Conjugating Enzyme E2 S Ubiquitin Carrier Protein S recombinant recombinant-proteins proteins protein

 

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