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UBE2H Protein, Human, Recombinant (GST)

UBE2H Protein, Human, Recombinant (GST)

产品编号 TMPJ-01047
别名: UBE2H, UbcH2, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin-Protein Ligase H, Ubiquitin Carrier Protein H, Ubiquitin-Conjugating Enzyme E2-20K

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

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UBE2H Protein, Human, Recombinant (GST)
规格 价格/CNY 货期 数量
10 μg ¥ 220 5日内发货
50 μg ¥ 580 5日内发货
500 μg ¥ 4,970 5日内发货
1 mg ¥ 7,110 5日内发货
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产品目录号及名称: UBE2H Protein, Human, Recombinant (GST) (TMPJ-01047)
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产品性质
产品描述 Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
种属 Human
表达系统 E. coli
标签 N-GST
蛋白编号 P62256
别名 UBE2H, UbcH2, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin-Protein Ligase H, Ubiquitin Carrier Protein H, Ubiquitin-Conjugating Enzyme E2-20K
氨基酸序列 Met1-Leu183
蛋白构建 Recombinant Human Ubiquitin-Conjugating Enzyme E2 H is produced by our E.coli expression system and the target gene encoding Met1-Leu183 is expressed with a GST tag at the N-terminus.
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 50 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

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Keywords

UBE2H Protein, Human, Recombinant (GST) UBE2H UbcH2 Ubiquitin-Conjugating Enzyme E2 H Ubiquitin-Protein Ligase H Ubiquitin Carrier Protein H Ubiquitin-Conjugating Enzyme E2-20K recombinant recombinant-proteins proteins protein

 

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