TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)

TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages.

规格	价格/CNY		数量
100 μg	￥ 3,100	5日内发货
500 μg	￥ 12,400	5日内发货
1 mg	￥ 20,700	5日内发货

规格

价格/CNY

货期

数量

100 μg

￥ 3,100

5日内发货

500 μg

￥ 12,400

5日内发货

1 mg

￥ 20,700

5日内发货

生物活性	1. Immobilized Human TRAIL, No Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human TRAIL R4, His Tag with the EC50 of 76.1ng/ml determined by ELISA (QC Test). 2. Human TRAIL R4, His Tag immobilized on CM5 Chip can bind Human TRAIL, No Tag with an affinity constant of 0.13 nM as determined in SPR assay.
产品描述	TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages.

种属	Human
表达系统	HEK293
标签	C-His-Avi
蛋白编号	Q9UBN6
别名	DCR2, TNFRSF10D, RSF10D, CD264, TRUNDD, TRAILR4
蛋白构建	Recombinant Human TRAIL R4/TNFRSF10D Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Ala56-His211.[Accession \|Q9UBN6]
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
分子量	The protein has a predicted MW of 19.4 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.

内毒素	Less than 1EU per μg by the LAL method.
缓冲液	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
存储	-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages.