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TPSB2 Protein, Human, Recombinant (His)

TPSB2 Protein, Human, Recombinant (His)

产品编号 TMPJ-00542
别名: Tryptase-2, Tryptase Beta-2, TPS2, TPSB2, Tryptase II, Tryptase β-2

Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

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TPSB2 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: TPSB2 Protein, Human, Recombinant (His) (TMPJ-00542)
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生物活性
技术参数
产品性质
生物活性 Loaded Anti-Human Tryptase mAb-Fc on AHC Biosensor, can bind Human TPSB2-His with an affinity constant of <10-3 nM as determined in BLI assay (Regularly tested)
产品描述 Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
种属 Human
表达系统 Human Cells
标签 C-6His
蛋白编号 AAH29356.1
别名 Tryptase-2, Tryptase Beta-2, TPS2, TPSB2, Tryptase II, Tryptase β-2
氨基酸序列 Ala19-Pro275
蛋白构建 Recombinant Human Tryptase Beta-2 is produced by our Mammalian expression system and the target gene encoding Ala19-Pro275 is expressed with a 6His tag at the C-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 30-35 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
存储

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

运输方式

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

研究背景 Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.

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Keywords

TPSB2 Protein, Human, Recombinant (His) Tryptase b-2 TPSB 2 TPS 2 Tryptase-2 TPSB-2 TPS-2 Tryptase Beta-2 TPS2 TPSB2 Tryptase II Tryptase β-2 recombinant recombinant-proteins proteins protein

 

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