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TNF R1 Protein, Mouse, Recombinant

TNF R1 Protein, Mouse, Recombinant

产品编号 TMPJ-00280
别名: Tnfrsf1a, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tnfr-1, Tumor necrosis factor receptor type I, Tnfr1

Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome

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TNF R1 Protein, Mouse, Recombinant
规格 价格/CNY 货期 数量
10 μg ¥ 740 5日内发货
50 μg ¥ 1,970 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: TNF R1 Protein, Mouse, Recombinant (TMPJ-00280)
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产品描述 Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome
种属 Mouse
表达系统 E. coli
标签 None
蛋白编号 P25118
别名 Tnfrsf1a, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tnfr-1, Tumor necrosis factor receptor type I, Tnfr1
氨基酸序列 Ile22-Ala212
蛋白构建 Recombinant Mouse Tumor Necrosis Factor Receptor I is produced by our E.coli expression system and the target gene encoding Ile22-Ala212 is expressed.
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 20-27 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.5.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome

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Keywords

TNF R1 Protein, Mouse, Recombinant Tnfrsf1a Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor 1 Tnfr-1 Tumor necrosis factor receptor type I Tnfr1 recombinant recombinant-proteins proteins protein

 

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