As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways.
生物活性 | Testing in progress |
产品描述 | As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways. |
种属 | Human |
表达系统 | HEK293 |
标签 | mFc |
蛋白编号 | AAH36460.1 |
别名 | thioredoxin-related transmembrane protein 1, PDIA11, TXNDC, TXNDC1, TMX |
蛋白构建 | A DNA sequence encoding the human TMX1 (AAH36460.1) (Met1-Ser180) was expressed with the Fc region of mouse IgG1 at the C-terminus. |
蛋白纯度 | > 90 % as determined by SDS-PAGE. |
分子量 | Approxiamtely 44.4 kDa |
内毒素 | < 1.0 EU per μg protein as determined by the LAL method. |
缓冲液 | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | As a thiol-based tumor suppressor, TMX1 increases mitochondrial ATP production and apoptosis progression. TMX1 is the first example of a topology-specific client protein redox catalyst acting both in the folding and in the degradative pathways. |
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TMX1 Protein, Human, Recombinant (mFc) thioredoxin-related transmembrane protein 1 PDIA11 PDIA-11 TXNDC TXNDC-1 PDIA 11 TXNDC1 TMX TXNDC 1 recombinant recombinant-proteins proteins protein