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TMIGD1 Protein, Human, Recombinant (mFc)

TMIGD1 Protein, Human, Recombinant (mFc)

产品编号 TMPY-04872
别名: transmembrane and immunoglobulin domain containing 1, TMIGD, UNQ9372

The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a novel candidate tumor suppressor gene and provides important insight into pathobiology of RCC that could lead to a better diagnosis and possible novel therapy for RCC. TMIGD1 controls cell migration, cell morphology, and protects renal epithelial cells from oxidative- and nutrient-deprivation-induced cell injury. TMIGD1 as a novel cell adhesion molecule expressed in kidney epithelial cells that protects kidney epithelial cells from oxidative cell injury to promote cell survival.

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TMIGD1 Protein, Human, Recombinant (mFc)
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货
1 mg ¥ 29,100 5日内发货
千万补贴 助力科研
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产品目录号及名称: TMIGD1 Protein, Human, Recombinant (mFc) (TMPY-04872)
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生物活性 Testing in progress
产品描述 The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a novel candidate tumor suppressor gene and provides important insight into pathobiology of RCC that could lead to a better diagnosis and possible novel therapy for RCC. TMIGD1 controls cell migration, cell morphology, and protects renal epithelial cells from oxidative- and nutrient-deprivation-induced cell injury. TMIGD1 as a novel cell adhesion molecule expressed in kidney epithelial cells that protects kidney epithelial cells from oxidative cell injury to promote cell survival.
种属 Human
表达系统 HEK293
标签 mFc
蛋白编号 Q6UXZ0-1
别名 transmembrane and immunoglobulin domain containing 1, TMIGD, UNQ9372
蛋白构建 A DNA sequence encoding the human TMIGD1 (NP_996663.1) (Met1-Pro220) was expressed with the Fc region of mouse IgG1 at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE.
分子量 Approxiamtely 47.5 kDa
内毒素 < 1.0 EU per μg protein as determined by the LAL method.
缓冲液 Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a novel candidate tumor suppressor gene and provides important insight into pathobiology of RCC that could lead to a better diagnosis and possible novel therapy for RCC. TMIGD1 controls cell migration, cell morphology, and protects renal epithelial cells from oxidative- and nutrient-deprivation-induced cell injury. TMIGD1 as a novel cell adhesion molecule expressed in kidney epithelial cells that protects kidney epithelial cells from oxidative cell injury to promote cell survival.

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Keywords

TMIGD1 Protein, Human, Recombinant (mFc) transmembrane and immunoglobulin domain containing 1 TMIGD UNQ-9372 UNQ 9372 UNQ9372 recombinant recombinant-proteins proteins protein

 

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