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TLK1 Protein, Human, Recombinant (His & GST)

TLK1 Protein, Human, Recombinant (His & GST)

产品编号 TMPY-04420
别名: KIAA0137, PKU-beta, tousled like kinase 1, PKU-β

Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper chromosome segregation and maintenance of diploid cells at mitosis in mammalian cells that could be mediated by reduced phosphorylation of histone H3 and condensation of chromosomes, although other explanations to the phenotype are possible.

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TLK1 Protein, Human, Recombinant (His & GST)
规格 价格/CNY 货期 数量
50 μg ¥ 3,170 5日内发货
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
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产品目录号及名称: TLK1 Protein, Human, Recombinant (His & GST) (TMPY-04420)
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参考文献
生物活性 Testing in progress
产品描述 Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper chromosome segregation and maintenance of diploid cells at mitosis in mammalian cells that could be mediated by reduced phosphorylation of histone H3 and condensation of chromosomes, although other explanations to the phenotype are possible.
种属 Human
表达系统 Baculovirus-Insect Cells
标签 His,GST
蛋白编号 Q9UKI8-1
别名 KIAA0137, PKU-beta, tousled like kinase 1, PKU-β
蛋白构建 A DNA sequence encoding the human TLK1 isoform 1 (Q9UKI8-1) (Met 1-Tyr 766) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
蛋白纯度 > 88 % as determined by SDS-PAGE
分子量 114 kDa (predicted)
内毒素 < 1.0 EU per μg of the protein as determined by the LAL method
缓冲液 Supplied as sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% glyPlease contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.

研究背景 Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper chromosome segregation and maintenance of diploid cells at mitosis in mammalian cells that could be mediated by reduced phosphorylation of histone H3 and condensation of chromosomes, although other explanations to the phenotype are possible.

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Keywords

TLK1 Protein, Human, Recombinant (His & GST) KIAA 0137 KIAA-0137 KIAA0137 PKU-beta tousled like kinase 1 PKU-β recombinant recombinant-proteins proteins protein

 

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