transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,980 | 现货 | ||
500 μg | ¥ 19,200 | 5日内发货 | ||
1 mg | ¥ 35,000 | 5日内发货 |
生物活性 | Human TGFBR1, mFc Tag captured on CM5 Chip via Protein A can bind Human Mature TGF beta 1, No Tag with an affinity constant of 0.35 μM as determined in SPR assay. |
产品描述 | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. |
种属 | Human |
表达系统 | HEK293 |
标签 | C-mFc-Avi |
蛋白编号 | P36897-1 |
别名 | tbetaR-I, TGFβRI, TGFbetaRI, LDS2A, ALK-5, TGF-beta RI, tβR-I, TGF-β RI, TGFR-1, TGFB1R1, ACVRLK4, LDS1A, AAT5, TGFBR1, TGF-bRI, SKR4 |
蛋白构建 | Recombinant Human TGFBR1 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus. It contains Leu34-Glu125.[Accession |P36897-1] |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | The protein has a predicted MW of 38.2 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储 |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. |
bottom
您可能有的问题的答案可以在重组蛋白操作手册中找到
TGFBR1 Protein, Human, Recombinant (mFc & Avi) ACVRLK 4 tbetaR-I TGFbRI TGFβRI TGFbetaRI TGFBR 1 LDS2A ALK-5 TGF-beta RI tβR-I ACVRLK-4 TGF-β RI TGFR-1 tbR-I TGF-b RI SKR-4 ALK 5 TGFB1R1 TGFBR-1 ACVRLK4 TGFR1 LDS1A AAT5 TGFBR1 TGF-bRI ALK5 AAT-5 SKR4 TGFR 1 SKR 4 AAT 5 recombinant recombinant-proteins proteins protein