Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
规格 | 价格/CNY | 货期 | 数量 | |
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10 μg | ¥ 1,170 | 现货 | ||
50 μg | ¥ 3,470 | 5日内发货 | ||
500 μg | ¥ 15,000 | 5日内发货 | ||
1 mg | ¥ 24,100 | 5日内发货 |
生物活性 |
Immobilized Mouse TGFBR2 -Fc at 10μg/ml (100 μl/well) can bind Mouse/Rat TGF-beta 2*.*: Biotinylated by NHS-biotin prior to testing. The ED50 of Mouse TGFBR2 -Fc is 0.136 ug/ml. (Regularly tested)
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产品描述 | Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system. |
种属 | Mouse,Rat |
表达系统 | Human Cells |
标签 | None |
蛋白编号 | P27090 |
别名 | transforming growth factor β-2, BSC-1 cell growth inhibitor, G-TSF, TGF-β-2, TGF-beta2, 转化生长因子, MGC116892, Polyergin, Cetermin, TGF-β2, TGFB2, TGF-beta-2, transforming growth factor beta-2, Glioblastoma-derived T-cell suppressor factor |
氨基酸序列 | Ala303-Ser414 |
蛋白构建 | Recombinant Mouse/Rat Transforming Growth Factor Beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed. |
蛋白纯度 |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
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分子量 | 12 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system. |
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TGF beta 2 Protein, Mouse/Rat, Recombinant MGC-116892 TGFB 2 transforming growth factor b-2 transforming growth factor β-2 BSC-1 cell growth inhibitor TGFB-2 G-TSF TGF-β-2 TGF-beta2 转化生长因子 MGC 116892 MGC116892 Polyergin TGF-b-2 Cetermin TGF-β2 TGFB2 TGF-beta-2 transforming growth factor beta-2 Glioblastoma-derived T-cell suppressor factor recombinant recombinant-proteins proteins protein