TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated

Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGFB2 could be a potential biomarker for screening, surveillance and prognosis in GC, and that TGFB2 might drive EMT in GC through the NGF/TrKs pathway. Overexpression of TGFB2 may drive EMT through the neuriterelated signaling and affect TMB levels by regulating the DNA damage repair pathways and immune infiltrates.TGF-β2 is an immune suppressor involvedin the development of immune tolerance, and recombinant TGF-β2 incubation is more potent than TGF-β1 or TGF-β3 incubation in suppressing macrophage inflammatory responses.

规格	价格/CNY		货期	数量
20 μg	￥ 5,730	5日内发货
100 μg	￥ 15,800	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 5,730

5日内发货

100 μg

￥ 15,800

5日内发货

生物活性

Immobilized Human TGFBR2-Fc at 2μg/ml (100 μl/well)can bind Biotinylated Human TGF-beta 2-Avi . The ED50 of Biotinylated Human TGF-beta 2-Avi is 18.30 ng/ml. (Regularly tested)

产品描述

种属	Human
表达系统	Human Cells
标签	N-Avi
蛋白编号	P61812
别名	G-TSF, 转化生长因子, Cetermin, Transforming growth factor beta-2 proprotein, Transforming growth factor β-2, TGF-β2, Glioblastoma-derived T-cell suppressor factor, TGFB2
氨基酸序列	Ala303-Ser414
蛋白构建	Biotinylated Recombinant Human Transforming Growth Factor Beta-2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed with a Avi tag at the N-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	10-14 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGFB2 could be a potential biomarker for screening, surveillance and prognosis in GC, and that TGFB2 might drive EMT in GC through the NGF/TrKs pathway. Overexpression of TGFB2 may drive EMT through the neuriterelated signaling and affect TMB levels by regulating the DNA damage repair pathways and immune infiltrates.TGF-β2 is an immune suppressor involvedin the development of immune tolerance, and recombinant TGF-β2 incubation is more potent than TGF-β1 or TGF-β3 incubation in suppressing macrophage inflammatory responses.

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TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated

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