TGF alpha Protein, Human, Recombinant

The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).

规格	价格/CNY		数量
20 μg	￥ 1,050	现货
100 μg	￥ 2,940	5日内发货
1 mg	￥ 19,100	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 1,050

现货

100 μg

￥ 2,940

5日内发货

1 mg

￥ 19,100

5日内发货

生物活性

1.Measured by its binding ability in a functional ELISA. Immobilized Human TGF-alpha at 2 μg/ml (100 μl/well) can bind Human EGFR hFc, the EC50 of Human EGFR hFc is 80-500 ng/mL. 2. Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.5-2.5 ng/mL.

产品描述

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P01135-1
别名	transforming growth factor α, 转化生长因子, transforming growth factor alpha, TGFa, TGF-α, TFGA
蛋白构建	A DNA sequence encoding the human TGFa (P01135-1) (Val40-Ala89) was expressed and purified.
蛋白纯度	> 90 % as determined by SDS-PAGE
分子量	Approxiamtely 5.6 kDa

内毒素	Please contact us for more information.
缓冲液	Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).

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TGF alpha Protein, Human, Recombinant

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